SCYX-7158, an Orally-Active Benzoxaborole for the Treatment of Stage 2 Human African Trypanosomiasis

Discovery of Novel Orally Bioavailable Oxaborole 6-Carboxamides That Demonstrate Cure in a Murine Model of Late-Stage Central Nervous System African Trypanosomiasis

(2010) B. Nare et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

N-myristoyltransferase inhibitors as new leads to treat sleeping sickness

(2010) Julie A. Frearson et al.   NATURE

Discovery of Novel Benzoxaborole-Based Potent Antitrypanosomal Agents

(2010) Dazhong Ding et al.   ACS Medicinal Chemistry Letters

NECT Is Next: Implementing the New Drug Combination Therapy for Trypanosoma brucei gambiense Sleeping Sickness

(2010) Oliver Yun et al.   PLoS Neglected Tropical Diseases

Trypanocidal drugs: mechanisms, resistance and new targets

(2009) Shane R. Wilkinson et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

NECT trial: more than a small victory over sleeping sickness

(2009) Jimmy Opigo et al.   LANCET

Nifurtimox-eflornithine combination therapy for second-stage African Trypanosoma brucei gambiense trypanosomiasis: a multicentre, randomised, phase III, non-inferiority trial

(2009) Gerardo Priotto et al.   LANCET

The Burden of Human African Trypanosomiasis

(2009) Eric M. Fèvre et al.   PLoS Neglected Tropical Diseases

Traversal of human and animal trypanosomes across the blood-brain barrier

(2008) Dennis J Grab et al.   JOURNAL OF NEUROVIROLOGY

Biopharmaceutics Classification System: Validation and Learnings of an in Vitro Permeability Assay

(2008) Victoria E. Thiel-Demby et al.   MOLECULAR PHARMACEUTICS

Eliminating Human African Trypanosomiasis: Where Do We Stand and What Comes Next?

(2008) Pere P Simarro et al.   PLOS MEDICINE