mCSF-Induced Microglial Activation Prevents Myelin Loss and Promotes Its Repair in a Mouse Model of Multiple Sclerosis

Five Decades of Cuprizone, an Updated Model to Replicate Demyelinating Diseases

(2019) Jose M. Vega-Riquer et al.   Current Neuropharmacology

Cell-specific deletion of C1qa identifies microglia as the dominant source of C1q in mouse brain

(2017) Maria I. Fonseca et al.   Journal of Neuroinflammation

Remyelination therapies: a new direction and challenge in multiple sclerosis

(2017) Jason R. Plemel et al.   NATURE REVIEWS DRUG DISCOVERY

Biological role of granulocyte macrophage colony-stimulating factor (GM-CSF) and macrophage colony-stimulating factor (M-CSF) on cells of the myeloid lineage

(2016) Irina Ushach et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Age-related myelin degradation burdens the clearance function of microglia during aging

(2016) Shima Safaiyan et al.   NATURE NEUROSCIENCE

Microglia and monocytes synergistically promote the transition from acute to chronic pain after nerve injury

(2016) Jiyun Peng et al.   Nature Communications

Inefficient clearance of myelin debris by microglia impairs remyelinating processes

(2015) Antoine Lampron et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Stimulation of Monocytes, Macrophages, and Microglia by Amphotericin B and Macrophage Colony-Stimulating Factor Promotes Remyelination

(2015) A. Doring et al.   JOURNAL OF NEUROSCIENCE

Pathologic and Protective Roles for Microglial Subsets and Bone Marrow- and Blood-Derived Myeloid Cells in Central Nervous System Inflammation

(2015) Agnieszka Wlodarczyk et al.   Frontiers in Immunology

A New Model of Cuprizone-Mediated Demyelination/Remyelination

(2014) Hilary H. Sachs et al.   ASN Neuro

TLR2 mediates phagocytosis and autophagy through JNK signaling pathway in Staphylococcus aureus-stimulated RAW264.7 cells

(2014) Lei Fang et al.   CELLULAR SIGNALLING

Phagocytosis of Microglia in the Central Nervous System Diseases

(2014) Ruying Fu et al.   MOLECULAR NEUROBIOLOGY

Glial response during cuprizone-induced de- and remyelination in the CNS: lessons learned

(2014) Viktoria Gudi et al.   Frontiers in Cellular Neuroscience

CSF-1 Receptor Signaling in Myeloid Cells

(2014) E. R. Stanley et al.   Cold Spring Harbor Perspectives in Biology

The Benefits and Detriments of Macrophages/Microglia in Models of Multiple Sclerosis

(2013) Khalil S. Rawji et al.   Clinical & Developmental Immunology

Minocycline reduces remyelination by suppressing ciliary neurotrophic factor expression after cuprizone-induced demyelination

(2013) Tatsuhide Tanaka et al.   JOURNAL OF NEUROCHEMISTRY

M-CSF increases proliferation and phagocytosis while modulating receptor and transcription factor expression in adult human microglia

(2013) Amy M Smith et al.   Journal of Neuroinflammation

M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination

(2013) Veronique E Miron et al.   NATURE NEUROSCIENCE

Modeling the heterogeneity of multiple sclerosis in animals

(2013) Sarah B. Simmons et al.   TRENDS IN IMMUNOLOGY

The effect of glia-glia interactions on oligodendrocyte precursor cell biology during development and in demyelinating diseases

(2013) Diego Clemente et al.   Frontiers in Cellular Neuroscience

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

(2012) Simon Yona et al.   IMMUNITY

Will the real multiple sclerosis please stand up?

(2012) Peter K. Stys et al.   NATURE REVIEWS NEUROSCIENCE

Effects of Myeloablation, Peripheral Chimerism, and Whole-Body Irradiation on the Entry of Bone Marrow-Derived Cells into the Brain

(2011) Antoine Lampron et al.   CELL TRANSPLANTATION

Demyelination and remyelination in anatomically distinct regions of the corpus callosum following cuprizone intoxication

(2011) Andrew J. Steelman et al.   NEUROSCIENCE RESEARCH

The corpus callosum: white matter or terra incognita

(2010) A Fitsiori et al.   BRITISH JOURNAL OF RADIOLOGY

Rostrocaudal Analysis of Corpus Callosum Demyelination and Axon Damage Across Disease Stages Refines Diffusion Tensor Imaging Correlations With Pathological Features

(2010) Mingqiang Xie et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Inflammation in Neurological Disorders: A Help or a Hindrance?

(2010) V. Wee Yong   NEUROSCIENTIST

Powerful beneficial effects of macrophage colony-stimulating factor on  -amyloid deposition and cognitive impairment in Alzheimer's disease

(2009) V. Boissonneault et al.   BRAIN

Macrophage colony-stimulating factor induces the proliferation and survival of macrophages via a pathway involving DAP12 and β-catenin

(2009) Karel Otero et al.   NATURE IMMUNOLOGY

Identification of soluble TREM-2 in the cerebrospinal fluid and its association with multiple sclerosis and CNS inflammation

(2008) Laura Piccio et al.   BRAIN

Debris clearance by microglia: an essential link between degeneration and regeneration

(2008) H. Neumann et al.   BRAIN

MRI identification of the rostral-caudal pattern of pathology within the corpus callosum in the cuprizone mouse model

(2007) Qi-Zhu Wu et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Circulating cell wall components derived from gram-negative, not gram-positive, bacteria cause a profound induction of the gene-encoding Toll-like receptor 2 in the CNS

(2003) Nathalie Laflamme et al.   JOURNAL OF NEUROCHEMISTRY