MicroRNA and Microvascular Complications of Diabetes

Plasma level of miR-93 is associated with higher risk to develop type 2 diabetic retinopathy

(2017) Hui-Ling Zou et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

MicroRNA-135a is involved in podocyte injury in a transient receptor potential channel 1-dependent manner

(2017) Xianggui Yang et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Variations in MicroRNA-25 Expression Influence the Severity of Diabetic Kidney Disease

(2017) Yunshuang Liu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Tissue-Specific MicroRNA Expression Patterns in Four Types of Kidney Disease

(2017) Maria Angeles Baker et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

microRNA-20b contributes to high glucose-induced podocyte apoptosis by targeting SIRT7

(2017) Xiaojing Wang et al.   Molecular Medicine Reports

MiR-29c/PRKCI Regulates Axonal Growth of Dorsal Root Ganglia Neurons Under Hyperglycemia

(2017) Longfei Jia et al.   MOLECULAR NEUROBIOLOGY

MicroRNA-200b Expression in the Vitreous Humor of Patients with Proliferative Diabetic Retinopathy

(2017) Amir Ramadan Gomaa et al.   OPHTHALMIC RESEARCH

MicroRNA-27a promotes podocyte injury via PPARγ-mediated β-catenin activation in diabetic nephropathy

(2017) Zhanmei Zhou et al.   Cell Death & Disease

Exosomal cargo including microRNA regulates sensory neuron to macrophage communication after nerve trauma

(2017) Raffaele Simeoli et al.   Nature Communications

MicroRNA-126: a promising novel biomarker in peripheral blood for diabetic retinopathy

(2017)   International Journal of Ophthalmology

Macro- and microvascular endothelial dysfunction in diabetes

(2017) Yi Shi et al.   Journal of Diabetes

A single-nucleotide polymorphism in the MicroRNA-146a gene is associated with diabetic nephropathy and sight-threatening diabetic retinopathy in Caucasian patients

(2016) Georgia Kaidonis et al.   ACTA DIABETOLOGICA

MicroRNA-126 and micro-/macrovascular complications of type 1 diabetes in the EURODIAB Prospective Complications Study

(2016) Federica Barutta et al.   ACTA DIABETOLOGICA

MicroRNAs as regulators of endothelial cell functions in cardiometabolic diseases

(2016) Elisa Araldi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Lipoprotein carriers of microRNAs

(2016) Danielle L. Michell et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Clinical verification of a novel urinary microRNA panal: 133b, -342 and -30 as biomarkers for diabetic nephropathy identified by bioinformatics analysis

(2016) Sanaa Eissa et al.   BIOMEDICINE & PHARMACOTHERAPY

Differential microRNA Profiles Predict Diabetic Nephropathy Progression in Taiwan

(2016) Hung-Yu Chien et al.   International Journal of Medical Sciences

Absence of miR-146a in Podocytes Increases Risk of Diabetic Glomerulopathy via Up-regulation of ErbB4 and Notch-1

(2016) Ha Won Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resveratrol Inhibits Diabetic-Induced Müller Cells Apoptosis through MicroRNA-29b/Specificity Protein 1 Pathway

(2016) Kaihong Zeng et al.   MOLECULAR NEUROBIOLOGY

Decreased expression of circulating microRNA-126 in patients with type 2 diabetic nephropathy: A potential blood-based biomarker

(2016) Ghada Al-Kafaji et al.   Experimental and Therapeutic Medicine

miR-93 regulates Msk2-mediated chromatin remodelling in diabetic nephropathy

(2016) Shawn S. Badal et al.   Nature Communications

MicroRNA-27a promotes renal tubulointerstitial fibrosis via suppressing PPARγ pathway in diabetic nephropathy

(2016) Xiaoyan Hou et al.   Oncotarget

MicroRNA-126 contributes to Niaspan treatment induced vascular restoration after diabetic retinopathy

(2016) Yang Wang et al.   Scientific Reports

Naringenin Ameliorated Kidney Injury through Let-7a/TGFBR1 Signaling in Diabetic Nephropathy

(2016) Ning Yan et al.   Journal of Diabetes Research

miRNAs in Urine Extracellular Vesicles as Predictors of Early-Stage Diabetic Nephropathy

(2016) Yijie Jia et al.   Journal of Diabetes Research

Dual Anti-Inflammatory and Anti-Angiogenic Action of miR-15a in Diabetic Retinopathy

(2016) Qi Wang et al.   EBioMedicine

Urinary Exosomal miRNA Signature in Type II Diabetic Nephropathy Patients

(2016) Denis Delić et al.   PLoS One

Deletion of miR-150 Exacerbates Retinal Vascular Overgrowth in High-Fat-Diet Induced Diabetic Mice

(2016) Liheng Shi et al.   PLoS One

LGR4 Is a Direct Target of MicroRNA-34a and Modulates the Proliferation and Migration of Retinal Pigment Epithelial ARPE-19 Cells

(2016) Qiang Hou et al.   PLoS One

MicroRNA-130b improves renal tubulointerstitial fibrosis via repression of Snail-induced epithelial-mesenchymal transition in diabetic nephropathy

(2016) Xiaoyan Bai et al.   Scientific Reports

Increased serum microRNAs are closely associated with the presence of microvascular complications in type 2 diabetes mellitus

(2016) Cheng Wang et al.   Scientific Reports

Altered microRNAs expression profiling in mice with diabetic neuropathic pain

(2015) Qingjuan Gong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Angiogenic MicroRNAs Linked to Incidence and Progression of Diabetic Retinopathy in Type 1 Diabetes

(2015) Anna Zampetaki et al.   DIABETES

Circulating TGF-β1–Regulated miRNAs and the Risk of Rapid Progression to ESRD in Type 1 Diabetes

(2015) Marcus G. Pezzolesi et al.   DIABETES

A genetic variant regulating miR-126 is associated with sight threatening diabetic retinopathy

(2015) Annie K McAuley et al.   Diabetes & Vascular Disease Research

The changes in miR-130b levels in human serum and the correlation with the severity of diabetic nephropathy

(2015) Chuan Lv et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

MicroRNA-26a inhibits TGF-β-induced extracellular matrix protein expression in podocytes by targeting CTGF and is downregulated in diabetic nephropathy

(2015) Kenichi Koga et al.   DIABETOLOGIA

Serum miR-21 may be a Potential Diagnostic Biomarker for Diabetic Nephropathy

(2015) J. Wang et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

MicroRNA-184 modulates canonical Wnt signaling through the regulation of frizzled-7 expression in the retina with ischemia-induced neovascularization

(2015) Yusuke Takahashi et al.   FEBS LETTERS

Promoter hypermethylation of let-7a-3 is relevant to its down-expression in diabetic nephropathy by targeting UHRF1

(2015) Rui Peng et al.   GENE

MicroRNA as Biomarkers and Diagnostics

(2015) Jin Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Noncoding RNAs in diabetes vascular complications

(2015) Cristina Beltrami et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Evidence for Epigenetic Regulation of Gene Expression and Function in Chronic Experimental Diabetic Neuropathy

(2015) Chu Cheng et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Deregulation of NF-кB–miR-146a negative feedback loop may be involved in the pathogenesis of diabetic neuropathy

(2015) Nasibeh Yousefzadeh et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Anti-Inflammatory Role of MicroRNA-146a in the Pathogenesis of Diabetic Nephropathy

(2015) K. Bhatt et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Urinary MicroRNA Profiling Predicts the Development of Microalbuminuria in Patients with Type 1 Diabetes

(2015) Christos Argyropoulos et al.   Journal of Clinical Medicine

Common polymorphisms in MIR146a, MIR128a and MIR27a genes contribute to neuropathy susceptibility in type 2 diabetes

(2014) Cinzia Ciccacci et al.   ACTA DIABETOLOGICA

Diabetic Kidney Disease: A Report From an ADA Consensus Conference

(2014) Katherine R. Tuttle et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

MiR-29b Protects Dorsal Root Ganglia Neurons from Diabetic Rat

(2014) Xiaona Zhang et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

The complexity of miRNA-mediated repression

(2014) A Wilczynska et al.   CELL DEATH AND DIFFERENTIATION

Serum MiRNA Biomarkers serve as a Fingerprint for Proliferative Diabetic Retinopathy

(2014) Shao Qing et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Linagliptin-Mediated DPP-4 Inhibition Ameliorates Kidney Fibrosis in Streptozotocin-Induced Diabetic Mice by Inhibiting Endothelial-to-Mesenchymal Transition in a Therapeutic Regimen

(2014) Keizo Kanasaki et al.   DIABETES

MiR-135a promotes renal fibrosis in diabetic nephropathy by regulating TRPC1

(2014) Feng He et al.   DIABETOLOGIA

miR-195 regulates SIRT1-mediated changes in diabetic retinopathy

(2014) Rokhsana Mortuza et al.   DIABETOLOGIA

Comparisons of microRNA expression profiles in vitreous humor between eyes with macular hole and eyes with proliferative diabetic retinopathy

(2014) Kazunari Hirota et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

MicroRNA-155 Deficiency Promotes Nephrin Acetylation and Attenuates Renal Damage in Hyperglycemia-Induced Nephropathy

(2014) Xu Lin et al.   INFLAMMATION

Hypoxia-Induced Deregulation of miR-126 and Its Regulative Effect on VEGF and MMP-9 Expression

(2014) Panpan Ye et al.   International Journal of Medical Sciences

Transforming Growth Factor β1 (TGF-β1) Enhances Expression of Profibrotic Genes through a Novel Signaling Cascade and MicroRNAs in Renal Mesangial Cells

(2014) Nancy E. Castro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Down-regulation of miR-34a alleviates mesangial proliferation in vitro and glomerular hypertrophy in early diabetic nephropathy mice by targeting GAS1

(2014) Le Zhang et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

MicroRNA-29a Promotion of Nephrin Acetylation Ameliorates Hyperglycemia-Induced Podocyte Dysfunction

(2014) C.-L. Lin et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

MicroRNA-21 in Glomerular Injury

(2014) J. Y. Lai et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Involvement of inflammation-related miR-155 and miR-146a in diabetic nephropathy: implications for glomerular endothelial injury

(2014) Youqun Huang et al.   BMC Nephrology

Nerve injury-induced upregulation of miR-21 in the primary sensory neurons contributes to neuropathic pain in rats

(2013) Atsushi Sakai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MicroRNA-dependent cross-talk between VEGF and HIF1α in the diabetic retina

(2013) Shukuan Ling et al.   CELLULAR SIGNALLING

Urinary sediment miRNA levels in adult nephrotic syndrome

(2013) Gang Wang et al.   CLINICA CHIMICA ACTA

Transforming Growth Factor-β–Induced Cross Talk Between p53 and a MicroRNA in the Pathogenesis of Diabetic Nephropathy

(2013) Supriya D. Deshpande et al.   DIABETES

miR-21 is a key therapeutic target for renal injury in a mouse model of type 2 diabetes

(2013) X. Zhong et al.   DIABETOLOGIA

Micro-RNA Expression in the Urinary Sediment of Patients with Chronic Kidney Diseases

(2013) Cheuk-Chun Szeto et al.   DISEASE MARKERS

MicroRNA-146 represses endothelial activation by inhibiting pro-inflammatory pathways

(2013) Henry S. Cheng et al.   EMBO Molecular Medicine

A potentially functional polymorphism in the regulatory region of let-7a-2 is associated with an increased risk for diabetic nephropathy

(2013) Ji Zhou et al.   GENE

FOG2 Protein Down-regulation by Transforming Growth Factor-β1-induced MicroRNA-200b/c Leads to Akt Kinase Activation and Glomerular Mesangial Hypertrophy Related to Diabetic Nephropathy

(2013) Jung Tak Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipoxins Attenuate Renal Fibrosis by Inducing let-7c and Suppressing TGF R1

(2013) E. P. Brennan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Transforming growth factor-β1-mediated renal fibrosis is dependent on the regulation of transforming growth factor receptor 1 expression by let-7b

(2013) Bo Wang et al.   KIDNEY INTERNATIONAL

MicroRNA-29b Inhibits Diabetic Nephropathy in db/db Mice

(2013) Hai-Yong Chen et al.   MOLECULAR THERAPY

The role of miR-146a in dorsal root ganglia neurons of experimental diabetic peripheral neuropathy

(2013) L. Wang et al.   NEUROSCIENCE

Diabetic peripheral neuropathy: Current perspective and future directions

(2013) Randhir Singh et al.   PHARMACOLOGICAL RESEARCH

Mechanisms of Diabetic Complications

(2013) Josephine M. Forbes et al.   PHYSIOLOGICAL REVIEWS

Functional Implications of MicroRNA-215 in TGF-β1-Induced Phenotypic Transition of Mesangial Cells by Targeting CTNNBIP1

(2013) Jiao Mu et al.   PLoS One

Urinary MicroRNA Profiling in the Nephropathy of Type 1 Diabetes

(2013) Christos Argyropoulos et al.   PLoS One

Urinary Exosomal MicroRNAs in Incipient Diabetic Nephropathy

(2013) Federica Barutta et al.   PLoS One

Urinary miR-29 Correlates with Albuminuria and Carotid Intima-Media Thickness in Type 2 Diabetes Patients

(2013) Hui Peng et al.   PLoS One

TGF-  Induces Acetylation of Chromatin and of Ets-1 to Alleviate Repression of miR-192 in Diabetic Nephropathy

(2013) M. Kato et al.   Science Signaling

Plasma miR-126 Is a Potential Biomarker for Early Prediction of Type 2 Diabetes Mellitus in Susceptible Individuals

(2013) Tao Zhang et al.   Biomed Research International

Transforming growth factor β1 represses proximal tubular cell microRNA-192 expression through decreased hepatocyte nuclear factor DNA binding

(2012) Robert H. Jenkins et al.   BIOCHEMICAL JOURNAL

Abated microRNA-195 expression protected mesangial cells from apoptosis in early diabetic renal injury in mice

(2012) Yu Q. Chen et al.   JOURNAL OF NEPHROLOGY

Inhibiting MicroRNA-192 Ameliorates Renal Fibrosis in Diabetic Nephropathy

(2012) S. Putta et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Alternative RISC assembly: Binding and repression of microRNA-mRNA duplexes by human Ago proteins

(2012) M. M. Janas et al.   RNA

MicroRNA-195 Promotes Apoptosis in Mouse Podocytes via Enhanced Caspase Activity Driven by BCL2 Insufficiency

(2011) Yu-Qiang Chen et al.   AMERICAN JOURNAL OF NEPHROLOGY

miR-21 and miR-214 Are Consistently Modulated during Renal Injury in Rodent Models

(2011) Laura Denby et al.   AMERICAN JOURNAL OF PATHOLOGY

Wnt Signaling Mediates Pathological Vascular Growth in Proliferative Retinopathy

(2011) Jing Chen et al.   CIRCULATION

MicroRNA-200b Regulates Vascular Endothelial Growth Factor-Mediated Alterations in Diabetic Retinopathy

(2011) K. McArthur et al.   DIABETES

miR-146a–Mediated Extracellular Matrix Protein Production in Chronic Diabetes Complications

(2011) Biao Feng et al.   DIABETES

MicroRNA-126 inhibits ischemia-induced retinal neovascularization via regulating angiogenic growth factors

(2011) Yanyan Bai et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

MicroRNA-29c Is a Signature MicroRNA under High Glucose Conditions That Targets Sprouty Homolog 1, and Itsin VivoKnockdown Prevents Progression of Diabetic Nephropathy

(2011) Jianyin Long et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-21 Orchestrates High Glucose-induced Signals to TOR Complex 1, Resulting in Renal Cell Pathology in Diabetes

(2011) Nirmalya Dey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TGF- /Smad3 Signaling Promotes Renal Fibrosis by Inhibiting miR-29

(2011) W. Qin et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Suppression of microRNA-29 Expression by TGF- 1 Promotes Collagen Expression and Renal Fibrosis

(2011) B. Wang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Smad3-Mediated Upregulation of miR-21 Promotes Renal Fibrosis

(2011) X. Zhong et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A microRNA circuit mediates transforming growth factor-β1 autoregulation in renal glomerular mesangial cells

(2011) Mitsuo Kato et al.   KIDNEY INTERNATIONAL

MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

(2011) Kasey C. Vickers et al.   NATURE CELL BIOLOGY

Regulation of NADPH Oxidase Activity Is Associated with miRNA-25-Mediated NOX4 Expression in Experimental Diabetic Nephropathy

(2010) Yibing Fu et al.   AMERICAN JOURNAL OF NEPHROLOGY

Plasma MicroRNA Profiling Reveals Loss of Endothelial MiR-126 and Other MicroRNAs in Type 2 Diabetes

(2010) Anna Zampetaki et al.   CIRCULATION RESEARCH

E-Cadherin Expression Is Regulated by miR-192/215 by a Mechanism That Is Independent of the Profibrotic Effects of Transforming Growth Factor- 

(2010) B. Wang et al.   DIABETES

miR-200a Prevents Renal Fibrogenesis Through Repression of TGF- 2 Expression

(2010) B. Wang et al.   DIABETES

High glucose down-regulates miR-29a to increase collagen IV production in HK-2 cells

(2010) Bin Du et al.   FEBS LETTERS

Identification of MicroRNA-93 as a Novel Regulator of Vascular Endothelial Growth Factor in Hyperglycemic Conditions

(2010) Jianyin Long et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Post-transcriptional Up-regulation of Tsc-22 by Ybx1, a Target of miR-216a, Mediates TGF-β-induced Collagen Expression in Kidney Cells

(2010) Mitsuo Kato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells

(2010) Nobuyoshi Kosaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of MicroRNA-192 Promotes Fibrogenesis in Diabetic Nephropathy

(2010) A. Krupa et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Diabetic retinopathy

(2010) Ning Cheung et al.   LANCET

The widespread regulation of microRNA biogenesis, function and decay

(2010) Jacek Krol et al.   NATURE REVIEWS GENETICS

MicroRNA-21 protects from mesangial cell proliferation induced by diabetic nephropathy in db/db mice

(2009) Zheng Zhang et al.   FEBS LETTERS

Delivery of MicroRNA-126 by Apoptotic Bodies Induces CXCL12-Dependent Vascular Protection

(2009) A. Zernecke et al.   Science Signaling

MicroRNA-377 is up-regulated and can lead to increased fibronectin production in diabetic nephropathy

(2008) Qiang Wang et al.   FASEB JOURNAL