The role of extracellular vesicles when innate meets adaptive

Human T H 17 cell development requires processing of dendritic cell–derived CXCL8 by neutrophil elastase

(2018) Yuri Souwer et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Human mast cells present antigen to autologous CD4 + T cells

(2018) Sahar Lotfi-Emran et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mast cell exosomes can suppress allergic reactions by binding to IgE

(2018) Guogang Xie et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Regulation and function of interleukin-36 cytokines

(2017) Esen Yonca Bassoy et al.   IMMUNOLOGICAL REVIEWS

Modulation of γδ T-cell activation by neutrophil elastase

(2017) Nadia Yasmín Towstyka et al.   IMMUNOLOGY

Mast cells acquire MHCII from dendritic cells during skin inflammation

(2017) Jan Dudeck et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neutrophil Microparticles Deliver Active Myeloperoxidase to Injured Mucosa To Inhibit Epithelial Wound Healing

(2017) Thomas W. Slater et al.   JOURNAL OF IMMUNOLOGY

Highly Selective Cleavage of Cytokines and Chemokines by the Human Mast Cell Chymase and Neutrophil Cathepsin G

(2017) Zhirong Fu et al.   JOURNAL OF IMMUNOLOGY

Exosomes from eosinophils autoregulate and promote eosinophil functions

(2017) José Antonio Cañas et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Granulocytes as modulators of dendritic cell function

(2017) Annelot Breedveld et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Exosomes from M1-Polarized Macrophages Potentiate the Cancer Vaccine by Creating a Pro-inflammatory Microenvironment in the Lymph Node

(2017) Lifang Cheng et al.   MOLECULAR THERAPY

EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research

(2017) Jan Van Deun et al.   NATURE METHODS

Trogocytosis of peptide–MHC class II complexes from dendritic cells confers antigen-presenting ability on basophils

(2017) Kensuke Miyake et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exosomes Derived From Natural Killer Cells Exert Therapeutic Effect in Melanoma

(2017) Liya Zhu et al.   Theranostics

The Enigma of Heat Shock Proteins in Immune Tolerance

(2017) Willem van Eden et al.   Frontiers in Immunology

Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease and cancer

(2016) R B Birge et al.   CELL DEATH AND DIFFERENTIATION

Dendritic cell–derived exosomes for cancer therapy

(2016) Jonathan M. Pitt et al.   JOURNAL OF CLINICAL INVESTIGATION

Regulation of chronic inflammatory and immune processes by extracellular vesicles

(2016) Paul D. Robbins et al.   JOURNAL OF CLINICAL INVESTIGATION

Psoriatic T cells recognize neolipid antigens generated by mast cell phospholipase delivered by exosomes and presented by CD1a

(2016) Ka Lun Cheung et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mast Cell Degranulation Is Accompanied by the Release of a Selective Subset of Extracellular Vesicles That Contain Mast Cell–Specific Proteases

(2016) Tom Groot Kormelink et al.   JOURNAL OF IMMUNOLOGY

IL-36γ is secreted in microparticles and exosomes by lung macrophages in response to bacteria and bacterial components

(2016) Melissa A. Kovach et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Inflammasome-Derived Exosomes Activate NF-κB Signaling in Macrophages

(2016) Yuehui Zhang et al.   JOURNAL OF PROTEOME RESEARCH

The lymph node neutrophil

(2016) Henry R. Hampton et al.   SEMINARS IN IMMUNOLOGY

Regulatory roles of mast cells in immune responses

(2016) Hideaki Morita et al.   Seminars in Immunopathology

Lysophosphatidylcholine plays critical role in allergic airway disease manifestation

(2016) Preeti Bansal et al.   Scientific Reports

Neutrophil-Derived Proteases Escalate Inflammation through Activation of IL-36 Family Cytokines

(2016) Conor M. Henry et al.   Cell Reports

Exosomes Mediate LTB4 Release during Neutrophil Chemotaxis

(2016) Ritankar Majumdar et al.   PLOS BIOLOGY

Mast Cell-Derived Exosomes Promote Th2 Cell Differentiation via OX40L-OX40 Ligation

(2016) Fei Li et al.   Journal of Immunology Research

Macrophage polarization in pathology

(2015) Antonio Sica et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Proteolytic Processing of Interleukin-1 Family Cytokines: Variations on a Common Theme

(2015) Inna S. Afonina et al.   IMMUNITY

Exosome secretion by eosinophils: A possible role in asthma pathogenesis

(2015) Carla Mazzeo et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mast cells and dendritic cells form synapses that facilitate antigen transfer for T cell activation

(2015) Amanda Carroll-Portillo et al.   JOURNAL OF CELL BIOLOGY

Functionally and morphologically distinct populations of extracellular vesicles produced by human neutrophilic granulocytes

(2015) A. M. Lorincz et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Potential effector and immunoregulatory functions of mast cells in mucosal immunity

(2015) L L Reber et al.   Mucosal Immunology

Neutrophil-derived microvesicles enter cartilage and protect the joint in inflammatory arthritis

(2015) Sarah E. Headland et al.   Science Translational Medicine

Microbe-dependent lymphatic migration of neutrophils modulates lymphocyte proliferation in lymph nodes

(2015) Henry R. Hampton et al.   Nature Communications

Mast Cell Promotion of T Cell-Driven Antigen-Induced Arthritis Despite Being Dispensable for Antibody-Induced Arthritis in Which T Cells Are Bypassed

(2015) Nadja Schubert et al.   Arthritis & Rheumatology

Regulation of Dendritic Cell Function in Inflammation

(2015) André Said et al.   Journal of Immunology Research

Mast Cells as Regulators of T Cell Responses

(2015) Silvia Bulfone-Paus et al.   Frontiers in Immunology

How Neutrophils Shape Adaptive Immune Responses

(2015) Pieter H. C. Leliefeld et al.   Frontiers in Immunology

The role of lymph node sinus macrophages in host defense

(2014) Mirela Kuka et al.   Annals of the New York Academy of Sciences

Indigenous enteric eosinophils control DCs to initiate a primary Th2 immune response in vivo

(2014) Derek K. Chu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mast Cell Function

(2014) Elaine Zayas Marcelino da Silva et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Mast Cell Migration from the Skin to the Draining Lymph Nodes upon Ultraviolet Irradiation Represents a Key Step in the Induction of Immune Suppression

(2014) S. N. Byrne et al.   JOURNAL OF IMMUNOLOGY

Hsp70 Translocates into the Plasma Membrane after Stress and Is Released into the Extracellular Environment in a Membrane-Associated Form that Activates Macrophages

(2014) V. L. Vega et al.   JOURNAL OF IMMUNOLOGY

Polymorphonuclear Neutrophil-Derived Ectosomes Interfere with the Maturation of Monocyte-Derived Dendritic Cells

(2014) C. Eken et al.   JOURNAL OF IMMUNOLOGY

Mast Cells Control the Expansion and Differentiation of IL-10–Competent B Cells

(2014) Francesca Mion et al.   JOURNAL OF IMMUNOLOGY

Functions of Heat Shock Proteins in Pathways of the Innate and Adaptive Immune System

(2014) Robert Julian Binder   JOURNAL OF IMMUNOLOGY

T helper cell IL-4 drives intestinal Th2 priming to oral peanut antigen, under the control of OX40L and independent of innate-like lymphocytes

(2014) D K Chu et al.   Mucosal Immunology

Regulatory B cells are induced by gut microbiota–driven interleukin-1β and interleukin-6 production

(2014) Elizabeth C Rosser et al.   NATURE MEDICINE

Functional significance of macrophage-derived exosomes in inflammation and pain

(2014) Marguerite K. McDonald et al.   PAIN

Mast cell-derived serine proteinase regulates T helper 2 polarization

(2014) Zhi-Qiang Liu et al.   Scientific Reports

Functions and Therapeutic Roles of Exosomes in Cancer

(2014) Jacob A. Tickner et al.   Frontiers in Oncology

The Multifaceted Functions of Neutrophils

(2013) Tanya N. Mayadas et al.   Annual Review of Pathology-Mechanisms of Disease

Neutrophil myeloperoxidase regulates T-cell-driven tissue inflammation in mice by inhibiting dendritic cell function

(2013) D. Odobasic et al.   BLOOD

Bee Venom Phospholipase A2 Induces a Primary Type 2 Response that Is Dependent on the Receptor ST2 and Confers Protective Immunity

(2013) Noah W. Palm et al.   IMMUNITY

T cell–derived microvesicles induce mast cell production of IL-24: Relevance to inflammatory skin diseases

(2013) Irit Shefler et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

Heterogeneity in Neutrophil Microparticles Reveals Distinct Proteome and Functional Properties

(2013) Jesmond Dalli et al.   MOLECULAR & CELLULAR PROTEOMICS

Dysregulation of alveolar macrophages unleashes dendritic cell–mediated mechanisms of allergic airway inflammation

(2013) J-F Lauzon-Joset et al.   Mucosal Immunology

Immunomodulatory Impact of Leishmania-Induced Macrophage Exosomes: A Comparative Proteomic and Functional Analysis

(2013) Kasra Hassani et al.   PLoS Neglected Tropical Diseases

Antibacterial effect of microvesicles released from human neutrophilic granulocytes

(2012) C. I. Timar et al.   BLOOD

The expanding role(s) of eosinophils in health and disease

(2012) E. A. Jacobsen et al.   BLOOD

Immune Cell-derived Vesicles: Modulators and Mediators of Inflammation

(2012) Esther N.M. Nolte-‘t Hoen et al.   CURRENT PHARMACEUTICAL DESIGN

Ectosomes of polymorphonuclear neutrophils activate multiple signaling pathways in macrophages

(2012) Ceylan Eken et al.   IMMUNOBIOLOGY

Recent Developments in Basophil Research: Do Basophils Initiate and Perpetuate Type 2 T-Helper Cell Responses?

(2012) A.A. van Beek et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Lpa2 Is a Negative Regulator of Both Dendritic Cell Activation and Murine Models of Allergic Lung Inflammation

(2012) J. Emo et al.   JOURNAL OF IMMUNOLOGY

Immune Surveillance Properties of Human NK Cell-Derived Exosomes

(2012) L. Lugini et al.   JOURNAL OF IMMUNOLOGY

Exosomes Isolated from Mycobacteria-Infected Mice or Cultured Macrophages Can Recruit and Activate Immune Cells In Vitro and In Vivo

(2012) P. P. Singh et al.   JOURNAL OF IMMUNOLOGY

Dynamics of dendritic cell-derived vesicles: high-resolution flow cytometric analysis of extracellular vesicle quantity and quality

(2012) E. N. M. Nolte-'t Hoen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Annexin A1 and the regulation of innate and adaptive immunity

(2012) Felicity N. E. Gavins et al.   Frontiers in Immunology

Mast cell synapses and exosomes: membrane contacts for information exchange

(2012) Amanda Carroll-Portillo   Frontiers in Immunology

Prostaglandins and Inflammation

(2011) Emanuela Ricciotti et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Leukotrienes and airway inflammation

(2011) Katsuhide Okunishi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Mast Cells Condition Dendritic Cells to Mediate Allograft Tolerance

(2011) Victor C. de Vries et al.   IMMUNITY

NK cells: immune cross-talk and therapeutic implications

(2011) Anshu Malhotra et al.   Immunotherapy

A subset of neutrophils in human systemic inflammation inhibits T cell responses through Mac-1

(2011) Janesh Pillay et al.   JOURNAL OF CLINICAL INVESTIGATION

CD169+ macrophages at the crossroads of antigen presentation

(2011) Luisa Martinez-Pomares et al.   TRENDS IN IMMUNOLOGY

Cancer Exosomes Trigger Fibroblast to Myofibroblast Differentiation

(2010) J. Webber et al.   CANCER RESEARCH

Mycobacterium tuberculosis Synergizes with ATP To Induce Release of Microvesicles and Exosomes Containing Major Histocompatibility Complex Class II Molecules Capable of Antigen Presentation

(2010) L. Ramachandra et al.   INFECTION AND IMMUNITY

Exosomes from human macrophages and dendritic cells contain enzymes for leukotriene biosynthesis and promote granulocyte migration

(2010) Julia Esser et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Ectosomes Released by Polymorphonuclear Neutrophils Induce a MerTK-dependent Anti-inflammatory Pathway in Macrophages

(2010) Ceylan Eken et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inflammatory dendritic cells—not basophils—are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen

(2010) Hamida Hammad et al.   JOURNAL OF EXPERIMENTAL MEDICINE

T Cell-Induced Mast Cell Activation: A Role for Microparticles Released from Activated T Cells

(2010) I. Shefler et al.   JOURNAL OF IMMUNOLOGY

Functional heterogeneity and differential priming of circulating neutrophils in human experimental endotoxemia

(2010) Janesh Pillay et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins

(2010) Caroline Subra et al.   JOURNAL OF LIPID RESEARCH

Exosomal Hsp70 Induces a Pro-Inflammatory Response to Foreign Particles Including Mycobacteria

(2010) Paras K. Anand et al.   PLoS One

Cell-cell cooperation at the T helper cell/mast cell immunological synapse

(2009) N. Gaudenzio et al.   BLOOD

Molecular mechanism and function of CD40/CD40L engagement in the immune system

(2009) Raul Elgueta et al.   IMMUNOLOGICAL REVIEWS

Inducible MHC Class II Expression by Mast Cells Supports Effector and Regulatory T Cell Activation

(2009) T. Kambayashi et al.   JOURNAL OF IMMUNOLOGY

Advances in mast cell biology: new understanding of heterogeneity and function

(2009) T C Moon et al.   Mucosal Immunology

Annexin 1 mediates the rapid anti-inflammatory effects of neutrophil-derived microparticles

(2008) J. Dalli et al.   BLOOD

B lymphocytes and macrophages release cell membrane deposited C3-fragments on exosomes with T cell response-enhancing capacity☆

(2008) Krisztián Papp et al.   MOLECULAR IMMUNOLOGY

Exosomes Derived from M. Bovis BCG Infected Macrophages Activate Antigen-Specific CD4+ and CD8+ T Cells In Vitro and In Vivo

(2008) Pramod K. Giri et al.   PLoS One