The expanding role(s) of eosinophils in health and disease

Cutting Edge: Eosinophils Do Not Contribute to Respiratory Syncytial Virus Vaccine-Enhanced Disease

(2014) E. M. Castilow et al.   JOURNAL OF IMMUNOLOGY

Eosinophil Deficiency Compromises Parasite Survival in Chronic Nematode Infection

(2014) V. Fabre et al.   JOURNAL OF IMMUNOLOGY

Pattern-recognition receptors in human eosinophils

(2012) Anne Månsson Kvarnhammar et al.   IMMUNOLOGY

CCR3 Blockade Attenuates Eosinophilic Ileitis and Associated Remodeling

(2011) Joanne C. Masterson et al.   AMERICAN JOURNAL OF PATHOLOGY

Eosinophils are necessary for pulmonary arterial remodeling in a mouse model of eosinophilic inflammation-induced pulmonary hypertension

(2011) M. Weng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Eosinophil Peroxidase Signals via Epidermal Growth Factor–2 to Induce Cell Proliferation

(2011) Marie-Therese Walsh et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Immunization induces activation of bone marrow eosinophils required for plasma cell survival

(2011) Van T. Chu et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Benralizumab – a humanized mAb to IL-5Rα with enhanced antibody-dependent cell-mediated cytotoxicity – a novel approach for the treatment of asthma

(2011) Aasia Ghazi et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Treatment of experimental autoimmune encephalomyelitis in SJL/J mice with a replicative HSV-1 vector expressing interleukin-5

(2011) M Nygårdas et al.   GENE THERAPY

Major Basic Protein from Eosinophils and Myeloperoxidase from Neutrophils Are Required for Protective Immunity to Strongyloides stercoralis in Mice

(2011) Amy E. O'Connell et al.   INFECTION AND IMMUNITY

A striking local esophageal cytokine expression profile in eosinophilic esophagitis

(2011) Carine Blanchard et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Tissue remodeling in patients with eosinophilic esophagitis: What lies beneath the surface?

(2011) Seema S. Aceves   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Eosinophilic esophagitis: Updated consensus recommendations for children and adults

(2011) Chris A. Liacouras et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

PPAR-γ signaling and IL-5 inhibition together prevent chronic rejection of MHC Class II–mismatched cardiac grafts

(2011) Yan Chen et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

The development of a sensitive and specific ELISA for mouse eosinophil peroxidase: Assessment of eosinophil degranulation ex vivo and in models of human disease

(2011) Sergei I. Ochkur et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Eosinophils Preserve Parasitic Nematode Larvae by Regulating Local Immunity

(2011) N. G. Gebreselassie et al.   JOURNAL OF IMMUNOLOGY

Eosinophils Regulate Dendritic Cells and Th2 Pulmonary Immune Responses following Allergen Provocation

(2011) E. A. Jacobsen et al.   JOURNAL OF IMMUNOLOGY

Cerebrospinal fluid findings in aquaporin-4 antibody positive neuromyelitis optica: Results from 211 lumbar punctures

(2011) S. Jarius et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Eosinophils are required for the maintenance of plasma cells in the bone marrow

(2011) Van Trung Chu et al.   NATURE IMMUNOLOGY

Eosinophils Increase Neuron Branching in Human and Murine Skin and In Vitro

(2011) Erin L. Foster et al.   PLoS One

Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis

(2011) D. Wu et al.   SCIENCE

Host-derived Interleukin-5 Promotes Adenocarcinoma-induced Malignant Pleural Effusion

(2010) Georgios T. Stathopoulos et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Eosinophils in innate immunity: an evolving story

(2010) Revital Shamri et al.   CELL AND TISSUE RESEARCH

Eosinophils in health and disease: the LIAR hypothesis

(2010) J. J. Lee et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Eosinophils as antigen-presenting cells in allergic upper airway disease

(2010) Praveen Akuthota et al.   Current Opinion in Allergy and Clinical Immunology

Inflammatory dendritic cells—not basophils—are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen

(2010) Hamida Hammad et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-33 Exacerbates Eosinophil-Mediated Airway Inflammation

(2010) B. Stolarski et al.   JOURNAL OF IMMUNOLOGY

Role of viral respiratory infections in asthma and asthma exacerbations

(2010) William W Busse et al.   LANCET

Selective Depletion of Eosinophils or Neutrophils in Mice Impacts the Efficiency of Apoptotic Cell Clearance in the Thymus

(2010) Hye-Jung Kim et al.   PLoS One

Thymic Indoleamine 2,3-Dioxygenase-Positive Eosinophils in Young Children

(2009) Meri K. Tulic et al.   AMERICAN JOURNAL OF PATHOLOGY

Treatment with a Novel Chemokine-Binding Protein or Eosinophil Lineage-Ablation Protects Mice from Experimental Colitis

(2009) Angélica T. Vieira et al.   AMERICAN JOURNAL OF PATHOLOGY

Mature human eosinophils express functional Notch ligands mediating eosinophil autocrine regulation

(2009) A. L. Radke et al.   BLOOD

A Novel Histologic Scoring System to Evaluate Mucosal Biopsies From Patients With Eosinophilic Esophagitis

(2009) Cheryl Protheroe et al.   Clinical Gastroenterology and Hepatology

Eosinophil Count Is Positively Correlated with Albumin Excretion Rate in Men with Type 2 Diabetes

(2009) M. Fukui et al.   Clinical Journal of the American Society of Nephrology

Mouse Eosinophils Possess Potent Antibacterial Properties In Vivo

(2009) S. N. Linch et al.   INFECTION AND IMMUNITY

Temporal Changes in Myeloid Cells in the Cervix during Pregnancy and Parturition

(2009) B. C. Timmons et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Limiting MHC Class II Expression to Dendritic Cells Alters the Ability to Develop Th2- Dependent Allergic Airway Inflammation

(2009) N. Niu et al.   JOURNAL OF IMMUNOLOGY

Mepolizumab and Exacerbations of Refractory Eosinophilic Asthma

(2009) Pranabashis Haldar et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mepolizumab for Prednisone-Dependent Asthma with Sputum Eosinophilia

(2009) Parameswaran Nair et al.   NEW ENGLAND JOURNAL OF MEDICINE

The role of eosinophil major basic protein in angiogenesis

(2008) I. Puxeddu et al.   ALLERGY

A new paradigm of eosinophil granulocytes: neuroimmune interactions

(2008) Ulrike Raap et al.   EXPERIMENTAL DERMATOLOGY

Major basic protein-1 promotes fibrosis of dystrophic muscle and attenuates the cellular immune response in muscular dystrophy

(2008) M. Wehling-Henricks et al.   HUMAN MOLECULAR GENETICS

Virus-induced eosinophil mediator release requires antigen-presenting and CD4+ T cells

(2008) Francis Davoine et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Strain-specific requirement for eosinophils in the recruitment of T cells to the lung during the development of allergic asthma

(2008) Elizabeth Rose Walsh et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2–MyD88 signal pathway in dendritic cells and enhances Th2 immune responses

(2008) De Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Allergic pulmonary inflammation in mice is dependent on eosinophil-induced recruitment of effector T cells

(2008) Elizabeth A. Jacobsen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Different regulation of eosinophil activity in Crohn's disease compared with ulcerative colitis

(2008) Maria Lampinen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Human eosinophils constitutively express multiple Th1, Th2, and immunoregulatory cytokines that are secreted rapidly and differentially

(2008) L. A. Spencer et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense

(2008) Shida Yousefi et al.   NATURE MEDICINE

Review: Tissue remodeling and angiogenesis in asthma: the role of the eosinophil

(2008) A.H. Nissim Ben Efraim et al.   Therapeutic Advances in Respiratory Disease

Esophageal Remodeling Develops as a Consequence of Tissue Specific IL-5-Induced Eosinophilia

(2007) Anil Mishra et al.   GASTROENTEROLOGY