Rebels with a cause: molecular features and physiological consequences of yeast prions

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Distinct α-Synuclein Strains Differentially Promote Tau Inclusions in Neurons

(2013) Jing L. Guo et al.   CELL

Heritable Remodeling of Yeast Multicellularity by an Environmentally Responsive Prion

(2013) Daniel L. Holmes et al.   CELL

Structural Definition Is Important for the Propagation of the Yeast [PSI+] Prion

(2013) Ricardo Marchante et al.   MOLECULAR CELL

Self-propagation of pathogenic protein aggregates in neurodegenerative diseases

(2013) Mathias Jucker et al.   NATURE

Critical Role of Amyloid-like Oligomers of Drosophila Orb2 in the Persistence of Memory

(2012) Amitabha Majumdar et al.   CELL

Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels

(2012) Masato Kato et al.   CELL

Prions are a common mechanism for phenotypic inheritance in wild yeasts

(2012) Randal Halfmann et al.   NATURE

The yeast prions [PSI+] and [URE3] are molecular degenerative diseases

(2012) Reed B. Wickner et al.   Prion

Conserved features of intermediates in amyloid assembly determine their benign or toxic states

(2012) R. Krishnan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sex, prions, and plasmids in yeast

(2012) A. C. Kelly et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Unifying Role for Prions in Neurodegenerative Diseases

(2012) S. B. Prusiner   SCIENCE

A Yeast Prion, Mod5, Promotes Acquired Drug Resistance and Cell Survival Under Environmental Stress

(2012) G. Suzuki et al.   SCIENCE

Motility and Segregation of Hsp104-Associated Protein Aggregates in Budding Yeast

(2011) Chuankai Zhou et al.   CELL

Segregation of Protein Aggregates Involves Actin and the Polarity Machinery

(2011) Beidong Liu et al.   CELL

MAVS Forms Functional Prion-like Aggregates to Activate and Propagate Antiviral Innate Immune Response

(2011) Fajian Hou et al.   CELL

[ PSI + ] Prion Transmission Barriers Protect Saccharomyces cerevisiae from Infection: Intraspecies 'Species Barriers'

(2011) David A. Bateman et al.   GENETICS

Opposing Effects of Glutamine and Asparagine Govern Prion Formation by Intrinsically Disordered Proteins

(2011) Randal Halfmann et al.   MOLECULAR CELL

Suicidal [PSI+] is a lethal yeast prion

(2011) R. P. McGlinchey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Essential Role of Coiled Coils for Aggregation and Activity of Q/N-Rich Prions and PolyQ Proteins

(2010) Ferdinando Fiumara et al.   CELL

The Polarisome Is Required for Segregation and Retrograde Transport of Protein Aggregates

(2010) Beidong Liu et al.   CELL

Aplysia CPEB Can Form Prion-like Multimers in Sensory Neurons that Contribute to Long-Term Facilitation

(2010) Kausik Si et al.   CELL

[NSI +]: a novel non-Mendelian nonsense suppressor determinant in Saccharomyces cerevisiae

(2010) Alsu F. Saifitdinova et al.   CURRENT GENETICS

HSP90 at the hub of protein homeostasis: emerging mechanistic insights

(2010) Mikko Taipale et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Conversion of a yeast prion protein to an infectious form in bacteria

(2010) S. J. Garrity et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Non-Mendelian determinant [ISP+] in yeast is a nuclear-residing prion form of the global transcriptional regulator Sfp1

(2010) T. Rogoza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hsp90 and Environmental Stress Transform the Adaptive Value of Natural Genetic Variation

(2010) D. F. Jarosz et al.   SCIENCE

A Size Threshold Limits Prion Transmission and Establishes Phenotypic Diversity

(2010) Aaron Derdowski et al.   SCIENCE

Epigenetics in the Extreme: Prions and the Inheritance of Environmentally Acquired Traits

(2010) Randal Halfmann et al.   SCIENCE

Biology of Amyloid: Structure, Function, and Regulation

(2010) Jason Greenwald et al.   STRUCTURE

Prions, protein homeostasis, and phenotypic diversity

(2010) Randal Halfmann et al.   TRENDS IN CELL BIOLOGY

A Systematic Survey Identifies Prions and Illuminates Sequence Features of Prionogenic Proteins

(2009) Simon Alberti et al.   CELL

A heritable switch in carbon source utilization driven by an unusual yeast prion

(2009) J. C.S. Brown et al.   GENES & DEVELOPMENT

The Spontaneous Appearance Rate of the Yeast Prion [PSI+] and Its Implications for the Evolution of the Evolvability Properties of the [PSI+] System

(2009) A. K. Lancaster et al.   GENETICS

The Yeast AAA+ Chaperone Hsp104 Is Part of a Network That Links the Actin Cytoskeleton with the Inheritance of Damaged Proteins

(2009) P. Tessarz et al.   MOLECULAR AND CELLULAR BIOLOGY

Transmission and spreading of tauopathy in transgenic mouse brain

(2009) Florence Clavaguera et al.   NATURE CELL BIOLOGY

The yeast global transcriptional co-repressor protein Cyc8 can propagate as a prion

(2009) Basant K. Patel et al.   NATURE CELL BIOLOGY

Hsp70 Structure, Function, Regulation and Influence on Yeast Prions

(2009) Deepak Sharma et al.   PROTEIN AND PEPTIDE LETTERS

Complex Adaptations Can Drive the Evolution of the Capacitor [PSI+], Even with Realistic Rates of Yeast Sex

(2009) Cortland K. Griswold et al.   PLoS Genetics

Hsp104, Hsp70 and Hsp40 interplay regulates formation, growth and elimination of Sup35 prions

(2008) James Shorter et al.   EMBO JOURNAL

Estimating the Per-Base-Pair Mutation Rate in the Yeast Saccharomyces cerevisiae

(2008) Gregory I. Lang et al.   GENETICS

Newly identified prion linked to the chromatin-remodeling factor Swi1 in Saccharomyces cerevisiae

(2008) Zhiqiang Du et al.   NATURE GENETICS

Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

(2008) Jia-Yi Li et al.   NATURE MEDICINE

Selective benefits of damage partitioning in unicellular systems and its effects on aging

(2008) N. Erjavec et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloid Fibrils of the HET-s(218-289) Prion Form a   Solenoid with a Triangular Hydrophobic Core

(2008) C. Wasmer et al.   SCIENCE

Adapting Proteostasis for Disease Intervention

(2008) William E. Balch et al.   SCIENCE

Hsp104 and ClpB: protein disaggregating machines

(2008) Shannon M. Doyle et al.   TRENDS IN BIOCHEMICAL SCIENCES

Prion Switching in Response to Environmental Stress

(2008) Jens Tyedmers et al.   PLOS BIOLOGY

Screening for Amyloid Aggregation by Semi-Denaturing Detergent-Agarose Gel Electrophoresis

(2008) Randal Halfmann et al.   Jove-Journal of Visualized Experiments