Programming self-organizing multicellular structures with synthetic cell-cell signaling

From morphogen to morphogenesis and back

(2017) Darren Gilmour et al.   NATURE

Microfluidic guillotine for single-cell wound repair studies

(2017) Lucas R. Blauch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Assembly of embryonic and extraembryonic stem cells to mimic embryogenesis in vitro

(2017) Sarah Ellys Harrison et al.   SCIENCE

Engineering Customized Cell Sensing and Response Behaviors Using Synthetic Notch Receptors

(2016) Leonardo Morsut et al.   CELL

Lineage specification in the mouse preimplantation embryo

(2016) Claire Chazaud et al.   DEVELOPMENT

Collective cell migration in development

(2016) Elena Scarpa et al.   JOURNAL OF CELL BIOLOGY

Tissue biology perspective on macrophages

(2016) Yasutaka Okabe et al.   NATURE IMMUNOLOGY

Bacterial lipids activate, synergize, and inhibit a developmental switch in choanoflagellates

(2016) Arielle Woznica et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthetic Morphogenesis

(2016) Brian P. Teague et al.   Cold Spring Harbor Perspectives in Biology

2- and 3-dimensional synthetic large-scale de novo patterning by mammalian cells through phase separation

(2016) Elise Cachat et al.   Scientific Reports

Positional information and reaction-diffusion: two big ideas in developmental biology combine

(2015) J. B. A. Green et al.   DEVELOPMENT

Synthetic lateral inhibition governs cell-type bifurcation with robust ratios

(2015) Mitsuhiro Matsuda et al.   Nature Communications

Paradoxical Signaling by a Secreted Molecule Leads to Homeostasis of Cell Levels

(2014) Yuval Hart et al.   CELL

Symmetry breaking, germ layer specification and axial organisation in aggregates of mouse embryonic stem cells

(2014) S. C. van den Brink et al.   DEVELOPMENT

A robust pipeline for rapid production of versatile nanobody repertoires

(2014) Peter C Fridy et al.   NATURE METHODS

Structural and energetic determinants of adhesive binding specificity in type I cadherins

(2014) Jeremie Vendome et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Programmable self-assembly in a thousand-robot swarm

(2014) M. Rubenstein et al.   SCIENCE

A self-organization framework for symmetry breaking in the mammalian embryo

(2013) Sebastian Wennekamp et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Chimeric Antigen Receptor–Modified T Cells for Acute Lymphoid Leukemia

(2013) Stephan A. Grupp et al.   NEW ENGLAND JOURNAL OF MEDICINE

Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

(2012) Maria Vinci et al.   BMC BIOLOGY

Origin of metazoan cadherin diversity and the antiquity of the classical cadherin/ -catenin complex

(2012) S. A. Nichols et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Specification and Simulation of Synthetic Multicelled Behaviors

(2012) Seunghee S. Jang et al.   ACS Synthetic Biology

A bacterial sulfonolipid triggers multicellular development in the closest living relatives of animals

(2012) Rosanna A Alegado et al.   eLife

Build life to understand it

(2010) Michael Elowitz et al.   NATURE

Dynamical patterning modules: a "pattern language" for development and evolution of multicellular form

(2009) Stuart A. Newman et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Synthetic morphology: prospects for engineered, self-constructing anatomies

(2008) Jamie A. Davies   JOURNAL OF ANATOMY

The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans

(2008) Nicole King et al.   NATURE

The Premetazoan Ancestry of Cadherins

(2008) Monika Abedin et al.   SCIENCE