Cell therapy-processing economics: small-scale microfactories as a stepping stone toward large-scale macrofactories

Characterization of human mesenchymal stem cells from multiple donors and the implications for large scale bioprocess development

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Innovation in the pharmaceutical industry: New estimates of R&D costs

(2016) Joseph A. DiMasi et al.   JOURNAL OF HEALTH ECONOMICS

Developing an automated robotic factory for novel stem cell therapy production

(2016) Qasim A Rafiq et al.   Regenerative Medicine

Development and production of good manufacturing practice grade human embryonic stem cell lines as source material for clinical application

(2016) P.A. De Sousa et al.   Stem Cell Research

Clinical manufacturing of CAR T cells: foundation of a promising therapy

(2016) Xiuyan Wang et al.   Molecular Therapy-Oncolytics

Challenges in the translation and commercialization of cell therapies

(2015) Brittany P. Dodson et al.   BMC BIOTECHNOLOGY

Stem Cell Therapies in Clinical Trials: Progress and Challenges

(2015) Alan Trounson et al.   Cell Stem Cell

The translation of cell-based therapies: clinical landscape and manufacturing challenges

(2015) Thomas RJ Heathman et al.   Regenerative Medicine

Concise Review: Review and Perspective of Cell Dosage and Routes of Administration From Preclinical and Clinical Studies of Stem Cell Therapy for Heart Disease

(2015) Samuel Golpanian et al.   Stem Cells Translational Medicine

Allogeneic Mesenchymal Stem Cells Restore Endothelial Function in Heart Failure by Stimulating Endothelial Progenitor Cells

(2015) Courtney Premer et al.   EBioMedicine

MSC-Based Product Characterization for Clinical Trials: An FDA Perspective

(2014) Michael Mendicino et al.   Cell Stem Cell

Chemically defined generation of human cardiomyocytes

(2014) Paul W Burridge et al.   NATURE METHODS

The Size of Mesenchymal Stem Cells is a Significant Cause of Vascular Obstructions and Stroke

(2014) Jianfeng Ge et al.   Stem Cell Reviews and Reports

Allogeneic cell therapy bioprocess economics and optimization: Single-use cell expansion technologies

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Culture of human mesenchymal stem cells on microcarriers in a 5 l stirred-tank bioreactor

(2013) Qasim A. Rafiq et al.   BIOTECHNOLOGY LETTERS

Current understanding and challenges in bioprocessing of stem cell-based therapies for regenerative medicine

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Chemically defined conditions for human iPSC derivation and culture

(2011) Guokai Chen et al.   NATURE METHODS

Directional migration of endothelial cells towards angiogenesis using polymer fibres in a 3D co-culture system

(2010) Afra Hadjizadeh et al.   Journal of Tissue Engineering and Regenerative Medicine

Allogeneic Mesenchymal Precursor Cell Therapy to Limit Remodeling After Myocardial Infarction: The Effect of Cell Dosage

(2009) Hirotsugu Hamamoto et al.   ANNALS OF THORACIC SURGERY

Osiris seals billion-dollar deal with Genzyme for cell therapy

(2009) George S. Mack   NATURE BIOTECHNOLOGY

Genzyme backs Osiris, despite Prochymal flop

(2009) Malorye Allison   NATURE BIOTECHNOLOGY

Culture of embryonic-like stem cells from human umbilical cord blood and onward differentiation to neural cells in vitro

(2008) Colin McGuckin et al.   Nature Protocols

Cell Culture Automation and Quality Engineering: A Necessary Partnership to Develop Optimized Manufacturing Processes for Cell-Based Therapies

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A brief definition of regenerative medicine

(2007) Chris Mason et al.   Regenerative Medicine