iPlasticity: Induced juvenile-like plasticity in the adult brain as a mechanism of antidepressants

Ketamine: translating mechanistic discoveries into the next generation of glutamate modulators for mood disorders

(2017) C A Zarate et al.   MOLECULAR PSYCHIATRY

Neuronal plasticity and neurotrophic factors in drug responses

(2017) E Castrén et al.   MOLECULAR PSYCHIATRY

Brain-derived neurotrophic factor in mood disorders and antidepressant treatments

(2017) Eero Castrén et al.   NEUROBIOLOGY OF DISEASE

Social Learning Requires Plasticity Enhanced by Fluoxetine Through Prefrontal Bdnf-TrkB Signaling to Limit Aggression Induced by Post-Weaning Social Isolation

(2017) Éva Mikics et al.   NEUROPSYCHOPHARMACOLOGY

The Combination of Long-term Ketamine and Extinction Training Contributes to Fear Erasure by Bdnf Methylation

(2017) Ling-Sha Ju et al.   Frontiers in Cellular Neuroscience

The Effect of Serotonin-Targeting Antidepressants on Neurogenesis and Neuronal Maturation of the Hippocampus Mediated via 5-HT1A and 5-HT4 Receptors

(2017) Eri Segi-Nishida   Frontiers in Cellular Neuroscience

Activity modifies adult brain maturity

(2017) Katsunori Kobayashi   Oncotarget

Rapid and stable changes in maturation-related phenotypes of the adult hippocampal neurons by electroconvulsive treatment

(2017) Yuki Imoto et al.   Molecular Brain

Citalopram amplifies the influence of living conditions on mood in depressed patients enrolled in the STAR*D study

(2017) F Chiarotti et al.   Translational Psychiatry

Transcriptomic immaturity of the hippocampus and prefrontal cortex in patients with alcoholism

(2017) Tomoyuki Murano et al.   Scientific Reports

Visualizing changes in brain-derived neurotrophic factor (BDNF) expression using bioluminescence imaging in living mice

(2017) Mamoru Fukuchi et al.   Scientific Reports

Spatial patterns and cell surface clusters in perineuronal nets

(2016) Nikita Arnst et al.   BRAIN RESEARCH

Removal of Perineuronal Nets Unlocks Juvenile Plasticity Through Network Mechanisms of Decreased Inhibition and Increased Gamma Activity

(2016) Kristian Kinden Lensjø et al.   JOURNAL OF NEUROSCIENCE

NMDAR inhibition-independent antidepressant actions of ketamine metabolites

(2016) Panos Zanos et al.   NATURE

Ketamine and Rapid-Acting Antidepressants: A Window into a New Neurobiology for Mood Disorder Therapeutics

(2015) Chadi G. Abdallah et al.   Annual Review of Medicine

A brief history of the development of antidepressant drugs: From monoamines to glutamate.

(2015) Todd M. Hillhouse et al.   EXPERIMENTAL AND CLINICAL PSYCHOPHARMACOLOGY

Behavioral flexibility in rats and mice: contributions of distinct frontocortical regions

(2015) D. A. Hamilton et al.   GENES BRAIN AND BEHAVIOR

Fluoxetine effects on molecular, cellular and behavioral endophenotypes of depression are driven by the living environment

(2015) S Alboni et al.   MOLECULAR PSYCHIATRY

Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder

(2015) Jerome Mertens et al.   NATURE

5-HT1A receptors on mature dentate gyrus granule cells are critical for the antidepressant response

(2015) Benjamin Adam Samuels et al.   NATURE NEUROSCIENCE

Stress and the social brain: behavioural effects and neurobiological mechanisms

(2015) Carmen Sandi et al.   NATURE REVIEWS NEUROSCIENCE

Role of the 5-HT4 receptor in chronic fluoxetine treatment-induced neurogenic activity and granule cell dematuration in the dentate gyrus

(2015) Yuki Imoto et al.   Molecular Brain

Chronic Fluoxetine Increases Extra-Hippocampal Neurogenesis in Adult Mice

(2015) B. D. Sachs et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

(R,S)-Ketamine Metabolites (R,S)-norketamine and (2S,6S)-hydroxynorketamine Increase the Mammalian Target of Rapamycin Function

(2014) Rajib K. Paul et al.   ANESTHESIOLOGY

Bistable Parvalbumin Circuits Pivotal for Brain Plasticity

(2014) Takao K. Hensch   CELL

Chronic fluoxetine treatment alters the structure, connectivity and plasticity of cortical interneurons

(2014) Ramon Guirado et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Mechanisms for modulation of neural plasticity and axon regeneration by chondroitin sulphate

(2014) S. Miyata et al.   JOURNAL OF BIOCHEMISTRY

ECT

(2014) Filip Bouckaert et al.   JOURNAL OF ECT

Depletion of Perineuronal Nets in the Amygdala to Enhance the Erasure of Drug Memories

(2014) Y.-X. Xue et al.   JOURNAL OF NEUROSCIENCE

Environment and Brain Plasticity: Towards an Endogenous Pharmacotherapy

(2014) Alessandro Sale et al.   PHYSIOLOGICAL REVIEWS

Fast-spiking, parvalbumin+ GABAergic interneurons: From cellular design to microcircuit function

(2014) H. Hu et al.   SCIENCE

Hippocampal Neurogenesis Regulates Forgetting During Adulthood and Infancy

(2014) K. G. Akers et al.   SCIENCE

Mice with altered BDNF signaling as models for mood disorders and antidepressant effects

(2014) Jesse S. O. Lindholm et al.   Frontiers in Behavioral Neuroscience

Transcriptomic evidence for immaturity of the prefrontal cortex in patients with schizophrenia

(2014) Hideo Hagihara et al.   Molecular Brain

Hippocampal structural and functional changes associated with electroconvulsive therapy response

(2014) C C Abbott et al.   Translational Psychiatry

The immature dentate gyrus represents a shared phenotype of mouse models of epilepsy and psychiatric disease

(2013) Rick Shin et al.   BIPOLAR DISORDERS

Depletion of Perineuronal Nets Enhances Recognition Memory and Long-Term Depression in the Perirhinal Cortex

(2013) C. Romberg et al.   JOURNAL OF NEUROSCIENCE

Disruption of the perineuronal net in the hippocampus or medial prefrontal cortex impairs fear conditioning

(2013) M. J. Hylin et al.   LEARNING & MEMORY

Parvalbumin-expressing basket-cell network plasticity induced by experience regulates adult learning

(2013) Flavio Donato et al.   NATURE

Fluoxetine-Induced Cortical Adult Neurogenesis

(2013) Koji Ohira et al.   NEUROPSYCHOPHARMACOLOGY

Deficiency of Schnurri-2, an MHC Enhancer Binding Protein, Induces Mild Chronic Inflammation in the Brain and Confers Molecular, Neuronal and Behavioral Phenotypes Related to Schizophrenia

(2013) Keizo Takao et al.   NEUROPSYCHOPHARMACOLOGY

Disruption of the expression of the proprotein convertase PC7 reduces BDNF production and affects learning and memory in mice

(2013) W. C. Wetsel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Electroconvulsive therapy-induced brain plasticity determines therapeutic outcome in mood disorders

(2013) J. Dukart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Excessive aggression as model of violence: a critical evaluation of current preclinical methods

(2013) Klaus A. Miczek et al.   PSYCHOPHARMACOLOGY

Neuronal plasticity and antidepressant actions

(2013) Eero Castrén et al.   TRENDS IN NEUROSCIENCES

Chronic fluoxetine treatment reduces parvalbumin expression and perineuronal nets in gamma-aminobutyric acidergic interneurons of the frontal cortex in adult mice

(2013) Koji Ohira et al.   Molecular Brain

Synaptosomal-associated protein 25 mutation induces immaturity of the dentate granule cells of adult mice

(2013) Koji Ohira et al.   Molecular Brain

Neuronal Network Plasticity and Recovery From Depression

(2013) Eero Castrén   JAMA Psychiatry

Immature Dentate Gyrus: An Endophenotype of Neuropsychiatric Disorders

(2013) Hideo Hagihara et al.   NEURAL PLASTICITY

Early-Life Insults Impair Parvalbumin Interneurons via Oxidative Stress: Reversal by N-Acetylcysteine

(2012) Jan-Harry Cabungcal et al.   BIOLOGICAL PSYCHIATRY

The perineuronal net and the control of CNS plasticity

(2012) Difei Wang et al.   CELL AND TISSUE RESEARCH

The cellular and synaptic location of activated TrkB in mouse hippocampus during limbic epileptogenesis

(2012) Jeffrey Helgager et al.   JOURNAL OF COMPARATIVE NEUROLOGY

BDNF Promotes Differentiation and Maturation of Adult-born Neurons through GABAergic Transmission

(2012) E. G. Waterhouse et al.   JOURNAL OF NEUROSCIENCE

Environmental enrichment restores neurogenesis and rapid acquisition in aged rats

(2012) Rachel B. Speisman et al.   NEUROBIOLOGY OF AGING

Dynamic neural systems enable adaptive, flexible memories

(2012) Marijn C.W. Kroes et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

p75 neurotrophin receptor signaling in nervous system injury and degeneration: paradox and opportunity

(2012) Carlos F. Ibáñez et al.   TRENDS IN NEUROSCIENCES

Effects of Spatial and Cognitive Enrichment on Activity Pattern and Learning Performance in Three Strains of Mice in the IntelliMaze

(2011) Alina Codita et al.   BEHAVIOR GENETICS

Automated test of behavioral flexibility in mice using a behavioral sequencing task in IntelliCage

(2011) Toshihiro Endo et al.   BEHAVIOURAL BRAIN RESEARCH

Brain-Derived Neurotrophic Factor Val66Met Allele Impairs Basal and Ketamine-Stimulated Synaptogenesis in Prefrontal Cortex

(2011) Rong-Jian Liu et al.   BIOLOGICAL PSYCHIATRY

Electroconvulsive seizure promotes spine maturation in newborn dentate granule cells in adult rat

(2011) Chunmei Zhao et al.   Developmental Neurobiology

Post-weaning social isolation induces abnormal forms of aggression in conjunction with increased glucocorticoid and autonomic stress responses

(2011) Mate Toth et al.   HORMONES AND BEHAVIOR

A preliminary naturalistic study of low-dose ketamine for depression and suicide ideation in the emergency department

(2011) Gregory Luke Larkin et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Fluoxetine for motor recovery after acute ischaemic stroke (FLAME): a randomised placebo-controlled trial

(2011) François Chollet et al.   LANCET NEUROLOGY

NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses

(2011) Anita E. Autry et al.   NATURE

Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation

(2011) Amar Sahay et al.   NATURE

Antidepressant Drugs Transactivate TrkB Neurotrophin Receptors in the Adult Rodent Brain Independently of BDNF and Monoamine Transporter Blockade

(2011) Tomi Rantamäki et al.   PLoS One

Rapid decrease in depressive symptoms with an N-methyl-d-aspartate antagonist in ECT-resistant major depression

(2011) Lobna Ibrahim et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Fear Erasure in Mice Requires Synergy Between Antidepressant Drugs and Extinction Training

(2011) N. N. Karpova et al.   SCIENCE

Neuronal Growth Cone Retraction Relies on Proneurotrophin Receptor Signaling Through Rac

(2011) K. Deinhardt et al.   Science Signaling

Food restriction enhances visual cortex plasticity in adulthood

(2011) Maria Spolidoro et al.   Nature Communications

Behavioral destabilization induced by the selective serotonin reuptake inhibitor fluoxetine

(2011) Katsunori Kobayashi et al.   Molecular Brain

The role of BDNF and its receptors in depression and antidepressant drug action: Reactivation of developmental plasticity

(2010) Eero Castrén et al.   Developmental Neurobiology

Experience-dependent reactivation of ocular dominance plasticity in the adult visual cortex

(2010) Laura Baroncelli et al.   EXPERIMENTAL NEUROLOGY

Rapid Resolution of Suicidal Ideation After a Single Infusion of anN-Methyl-D-Aspartate Antagonist in Patients With Treatment-Resistant Major Depressive Disorder

(2010) Nancy DiazGranados et al.   JOURNAL OF CLINICAL PSYCHIATRY

Reducing Intracortical Inhibition in the Adult Visual Cortex Promotes Ocular Dominance Plasticity

(2010) A. Harauzov et al.   JOURNAL OF NEUROSCIENCE

Implications of the Functional Integration of Adult-Born Hippocampal Neurons in Anxiety-Depression Disorders

(2010) Denis J. David et al.   NEUROSCIENTIST

Role of the Amygdala in Antidepressant Effects on Hippocampal Cell Proliferation and Survival and on Depression-like Behavior in the Rat

(2010) Jorge E. Castro et al.   PLoS One

Reversal of hippocampal neuronal maturation by serotonergic antidepressants

(2010) K. Kobayashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lynx1, a Cholinergic Brake, Limits Plasticity in Adult Visual Cortex

(2010) H. Morishita et al.   SCIENCE

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

(2010) N. Li et al.   SCIENCE

Co-Treatment with Diazepam Prevents the Effects of Fluoxetine on the Proliferation and Survival of Hippocampal Dentate Granule Cells

(2009) Xuefei Wu et al.   BIOLOGICAL PSYCHIATRY

Repeated electroconvulsive seizures increase the total number of synapses in adult male rat hippocampus

(2009) Fenghua Chen et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Antidepressant Actions of Histone Deacetylase Inhibitors

(2009) H. E. Covington et al.   JOURNAL OF NEUROSCIENCE

The neurobiological properties of tianeptine (Stablon): from monoamine hypothesis to glutamatergic modulation

(2009) B S McEwen et al.   MOLECULAR PSYCHIATRY

Parvalbumin neurons and gamma rhythms enhance cortical circuit performance

(2009) Vikaas S. Sohal et al.   NATURE

Neurogenesis-Dependent and -Independent Effects of Fluoxetine in an Animal Model of Anxiety/Depression

(2009) Denis J. David et al.   NEURON

Perineuronal Nets Protect Fear Memories from Erasure

(2009) N. Gogolla et al.   SCIENCE

A trans-dimensional approach to the behavioral aspects of depression

(2009) João M. Bessa   Frontiers in Behavioral Neuroscience

Multiple functions of precursor BDNF to CNS neurons: negative regulation of neurite growth, spine formation and cell survival

(2009) Hisatsugu Koshimizu et al.   Molecular Brain

Early social deprivation induces disturbed social communication and violent aggression in adulthood.

(2008) Máté Tóth et al.   BEHAVIORAL NEUROSCIENCE

Influence of environmental manipulation on exploratory behaviour in male BDNF knockout mice

(2008) Shun-Wei Zhu et al.   BEHAVIOURAL BRAIN RESEARCH

Drug-Dependent Requirement of Hippocampal Neurogenesis in a Model of Depression and of Antidepressant Reversal

(2008) Alexandre Surget et al.   BIOLOGICAL PSYCHIATRY

Acute Hippocampal Brain-Derived Neurotrophic Factor Restores Motivational and Forced Swim Performance After Corticosterone

(2008) Shannon L. Gourley et al.   BIOLOGICAL PSYCHIATRY

Differential regulation of central BDNF protein levels by antidepressant and non-antidepressant drug treatments

(2008) Darrick T. Balu et al.   BRAIN RESEARCH

Critical period revisited: impact on vision

(2008) Hirofumi Morishita et al.   CURRENT OPINION IN NEUROBIOLOGY

Chronic low dose corticosterone exposure decreased hippocampal cell proliferation, volume and induced anxiety and depression like behaviours in mice

(2008) Fraser Murray et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Switching to Another SSRI or to Venlafaxine With or Without Cognitive Behavioral Therapy for Adolescents With SSRI-Resistant Depression

(2008) David Brent   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Chronic Fluoxetine Stimulates Maturation and Synaptic Plasticity of Adult-Born Hippocampal Granule Cells

(2008) J.-W. Wang et al.   JOURNAL OF NEUROSCIENCE

Chronic fluoxetine treatment alters behavior, but not adult hippocampal neurogenesis, in BALB/cJ mice

(2008) G-J Huang et al.   MOLECULAR PSYCHIATRY

The mood-improving actions of antidepressants do not depend on neurogenesis but are associated with neuronal remodeling

(2008) J M Bessa et al.   MOLECULAR PSYCHIATRY

Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain

(2008) Itaru Imayoshi et al.   NATURE NEUROSCIENCE

Keeping ‘Trk’ of Antidepressant Actions

(2008) Mounira Banasr et al.   NEURON

TrkB Regulates Hippocampal Neurogenesis and Governs Sensitivity to Antidepressive Treatment

(2008) Yun Li et al.   NEURON

Nortriptyline mediates behavioral effects without affecting hippocampal cytogenesis in a genetic rat depression model

(2008) Åsa Petersén et al.   NEUROSCIENCE LETTERS

The Antidepressant Fluoxetine Restores Plasticity in the Adult Visual Cortex

(2008) J. F. M. Vetencourt et al.   SCIENCE

Alpha-CaMKII deficiency causes immature dentate gyrus, a novel candidate endophenotype of psychiatric disorders

(2008) Nobuyuki Yamasaki et al.   Molecular Brain

Selective Loss of Brain-Derived Neurotrophic Factor in the Dentate Gyrus Attenuates Antidepressant Efficacy

(2007) Megumi Adachi et al.   BIOLOGICAL PSYCHIATRY