Expression of PD-1 and Tim-3 markers of T-cell exhaustion is associated with CD4 dynamics during the course of untreated and treated HIV infection

HCV coinfection contributes to HIV pathogenesis by increasing immune exhaustion in CD8 T-cells

(2017) Norma Rallón et al.   PLoS One

Increase in frequencies of circulating Th-17 cells correlates with microbial translocation, immune activation and exhaustion in HIV-1 infected patients with poor CD4 T-cell reconstitution

(2016) Ranjini Valiathan et al.   IMMUNOBIOLOGY

Inflammation Perturbs the IL-7 Axis, Promoting Senescence and Exhaustion that Broadly Characterize Immune Failure in Treated HIV Infection

(2016) Carey L. Shive et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Exhaustion of Activated CD8 T Cells Predicts Disease Progression in Primary HIV-1 Infection

(2016) Matthias Hoffmann et al.   PLoS Pathogens

Programmed death-1 expression on CD4+ and CD8+ T cells in treated and untreated HIV disease

(2014) Leslie R. Cockerham et al.   AIDS

Programmed Death-1 Is a Marker for Abnormal Distribution of Naive/Memory T Cell Subsets in HIV-1 Infection

(2013) G. Breton et al.   JOURNAL OF IMMUNOLOGY

Molecular signatures of T-cell inhibition in HIV-1 infection

(2013) Marie Larsson et al.   Retrovirology

Inhibitory Receptor Expression Depends More Dominantly on Differentiation and Activation than “Exhaustion” of Human CD8 T Cells

(2013) Amandine Legat et al.   Frontiers in Immunology

HIV-Induced T-Cell Activation/Exhaustion in Rectal Mucosa Is Controlled Only Partially by Antiretroviral Treatment

(2012) Cesar Mauricio Rueda et al.   PLoS One

HIV-1 Induced Bystander Apoptosis

(2012) Himanshu Garg et al.   Viruses-Basel

High T-cell immune activation and immune exhaustion among individuals with suboptimal CD4 recovery after 4 years of antiretroviral therapy in an African cohort

(2011) Damalie Nakanjako et al.   BMC INFECTIOUS DISEASES

Pro- and anti-apoptotic CD95 signaling in T cells

(2011) Maren Paulsen et al.   Cell Communication and Signaling

Immune Exhaustion Occurs Concomitantly With Immune Activation and Decrease in Regulatory T Cells in Viremic Chronically HIV-1–Infected Patients

(2010) Meenakshi Sachdeva et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Identification of PD-1 as a Unique Marker for Failing Immune Reconstitution in HIV-1–Infected Patients on Treatment

(2010) Katharina Grabmeier-Pfistershammer et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection

(2010) H.-T. Jin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Revisiting Immune Exhaustion During HIV Infection

(2010) Alka Khaitan et al.   Current HIV/AIDS Reports

New insights on the role of apoptosis and autophagy in HIV pathogenesis

(2009) M.-L. Gougeon et al.   APOPTOSIS

Programmed death (PD)-1 molecule and its ligand PD-L1 distribution among memory CD4 and CD8 T cell subsets in human immunodeficiency virus-1-infected individuals

(2009) G. Rosignoli et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Role of the Fas/FasL pathway in HIV or SIV disease

(2009) Bhawna Poonia et al.   Retrovirology

Emerging Concepts in the Immunopathogenesis of AIDS

(2008) Daniel C. Douek et al.   Annual Review of Medicine

Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection

(2008) R. Brad Jones et al.   JOURNAL OF EXPERIMENTAL MEDICINE