HCV coinfection contributes to HIV pathogenesis by increasing immune exhaustion in CD8 T-cells

Natural history and treatment of HCV/HIV coinfection: Is it time to change paradigms?

(2015) Joop E. Arends et al.   JOURNAL OF HEPATOLOGY

Success and failure of the cellular immune response against HIV-1

(2015) Stephen A Migueles et al.   NATURE IMMUNOLOGY

Immune Activation Response in Chronic HIV-Infected Patients: Influence of Hepatitis C Virus Coinfection

(2015) Mercedes Márquez et al.   PLoS One

Influence of hepatitis C virus coinfection on CD4+ T cells of HIV-infected patients receiving HAART

(2014) Konstantin V. Shmagel et al.   AIDS

Programmed death-1 expression on CD4+ and CD8+ T cells in treated and untreated HIV disease

(2014) Leslie R. Cockerham et al.   AIDS

Coinhibitory receptors and CD8 T cell exhaustion in chronic infections

(2014) Vijay K. Kuchroo et al.   Current Opinion in HIV and AIDS

Expression of inhibitory markers is increased on effector memory T cells during hepatitis C virus/HIV coinfection as compared to hepatitis C virus or HIV monoinfection

(2013) Banishree Saha et al.   AIDS

CD4+T-cell depletion in HIV infection: mechanisms of immunological failure

(2013) Afam A. Okoye et al.   IMMUNOLOGICAL REVIEWS

Programmed Death-1 Is a Marker for Abnormal Distribution of Naive/Memory T Cell Subsets in HIV-1 Infection

(2013) G. Breton et al.   JOURNAL OF IMMUNOLOGY

Complementary Role of HCV and HIV in T-Cell Activation and Exhaustion in HIV/HCV Coinfection

(2013) Thijs Feuth et al.   PLoS One

Effects of HCV on Basal and Tat-Induced HIV LTR Activation

(2013) Satarupa Sengupta et al.   PLoS One

Effect of Hepatitis C Infection on HIV-Induced Apoptosis

(2013) Tomasz Laskus et al.   PLoS One

Molecular signatures of T-cell inhibition in HIV-1 infection

(2013) Marie Larsson et al.   Retrovirology

Inhibitory Receptor Expression Depends More Dominantly on Differentiation and Activation than “Exhaustion” of Human CD8 T Cells

(2013) Amandine Legat et al.   Frontiers in Immunology

Crosstalk between HIV and hepatitis C virus during co-infection

(2012) Paul J Rider et al.   BMC Medicine

Effect of HCV Infection on Cause-Specific Mortality After HIV Seroconversion, Before and After 1997

(2012) Jannie van der Helm et al.   GASTROENTEROLOGY

HIV-1 Induced Bystander Apoptosis

(2012) Himanshu Garg et al.   Viruses-Basel

A siege of hepatitis: Immune boost for viral hepatitis

(2011) Benoît Callendret et al.   NATURE MEDICINE

HIV/hepatitis C coinfection natural history and disease progression

(2011) Maria D. Hernandez et al.   Current Opinion in HIV and AIDS

HCV-specific T cells in HCV/HIV co-infection show elevated frequencies of dual Tim-3/PD-1 expression that correlate with liver disease progression

(2010) Bahareh Vali et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Immune Exhaustion Occurs Concomitantly With Immune Activation and Decrease in Regulatory T Cells in Viremic Chronically HIV-1–Infected Patients

(2010) Meenakshi Sachdeva et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Activation of CD8 T Cells Predicts Progression of HIV Infection in Women Coinfected with Hepatitis C Virus

(2010) Andrea Kovacs et al.   JOURNAL OF INFECTIOUS DISEASES

Limited CD4+ T cell proliferation leads to preservation of CD4+ T cell counts in SIV-infected sooty mangabeys

(2010) M. L. Chan et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Revisiting Immune Exhaustion During HIV Infection

(2010) Alka Khaitan et al.   Current HIV/AIDS Reports

Programmed death (PD)-1 molecule and its ligand PD-L1 distribution among memory CD4 and CD8 T cell subsets in human immunodeficiency virus-1-infected individuals

(2009) G. Rosignoli et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Risk of Developing Specific AIDS‐Defining Illnesses in Patients Coinfected with HIV and Hepatitis C Virus With or Without Liver Cirrhosis

(2009) Antonella d’Arminio Monforte et al.   CLINICAL INFECTIOUS DISEASES

Effects of HCV co-infection on apoptosis of CD4+T-cells in HIV-positive patients

(2009) Christian Körner et al.   CLINICAL SCIENCE

High Levels of Chronic Immune Activation in the T-Cell Compartments of Patients Coinfected with Hepatitis C Virus and Human Immunodeficiency Virus Type 1 and on Highly Active Antiretroviral Therapy Are Reverted by Alpha Interferon and Ribavirin Treatment

(2009) V. D. Gonzalez et al.   JOURNAL OF VIROLOGY

Role of the Fas/FasL pathway in HIV or SIV disease

(2009) Bhawna Poonia et al.   Retrovirology

Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection

(2008) R. Brad Jones et al.   JOURNAL OF EXPERIMENTAL MEDICINE