HIV-1 Induced Bystander Apoptosis

HIV-1 gp41 fusogenic function triggers autophagy in uninfected cells

(2014) Mélanie Denizot et al.   Autophagy

Autophagy: An overlooked mechanism of HIV-1 pathogenesis and NeuroAIDS?

(2014) Stephen A. Spector et al.   Autophagy

Early Resolution of Acute Immune Activation and Induction of PD-1 in SIV-Infected Sooty Mangabeys Distinguishes Nonpathogenic from Pathogenic Infection in Rhesus Macaques

(2014) J. D. Estes et al.   JOURNAL OF IMMUNOLOGY

HIV-infected T cells are migratory vehicles for viral dissemination

(2012) Thomas T. Murooka et al.   NATURE

The HR2 polymorphism N140I in the HIV-1 gp41 combined with the HR1 V38A mutation is associated with a less cytopathic phenotype

(2012) Francesc Cunyat et al.   Retrovirology

Viral envelope protein folding and membrane hemifusion are enhanced by the conserved loop region of HIV-1 gp41

(2011) Avraham Ashkenazi et al.   FASEB JOURNAL

Short-term additional enfuvirtide therapy is associated with a greater immunological recovery in HIV very late presenters: a controlled pilot study

(2011) S. Bonora et al.   INFECTION

HIV ENV Glycoprotein-mediated Bystander Apoptosis Depends on Expression of the CCR5 Co-receptor at the Cell Surface and ENV Fusogenic Activity

(2011) Anjali Joshi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Is Microbial Translocation a Cause or Consequence of HIV Disease Progression?

(2011) Andrew D. Redd et al.   JOURNAL OF INFECTIOUS DISEASES

Low levels of SIV infection in sooty mangabey central memory CD4+ T cells are associated with limited CCR5 expression

(2011) Mirko Paiardini et al.   NATURE MEDICINE

Increased Rate of CD4+ T-Cell Decline and Faster Time to Antiretroviral Therapy in HIV-1 Subtype CRF01_AE Infected Seroconverters in Singapore

(2011) Oon Tek Ng et al.   PLoS One

The utility of the new generation of humanized mice to study HIV-1 infection: transmission, prevention, pathogenesis, and treatment

(2011) Bradford K Berges et al.   Retrovirology

Comparison of in vivo and in vitro evolution of CCR5 to CXCR4 coreceptor use of primary human immunodeficiency virus type 1 variants

(2011) Diana Edo-Matas et al.   VIROLOGY

Targeting the HIV entry, assembly and release pathways for anti-HIV gene therapy

(2011) Anjali Joshi et al.   VIROLOGY

Single amino acid change in gp41 region of HIV-1 alters bystander apoptosis and CD4 decline in humanized mice

(2011) Himanshu Garg et al.   Virology Journal

IRGM Is a Common Target of RNA Viruses that Subvert the Autophagy Network

(2011) Isabel Pombo Grégoire et al.   PLoS Pathogens

Abortive HIV Infection Mediates CD4 T Cell Depletion and Inflammation in Human Lymphoid Tissue

(2010) Gilad Doitsh et al.   CELL

Autophagy in infection

(2010) Vojo Deretic   CURRENT OPINION IN CELL BIOLOGY

Extreme Genetic Divergence Is Required for Coreceptor Switching in HIV-1 Subtype C

(2010) Mia Coetzer et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Caveolin-1 Modulates HIV-1 Envelope-Induced Bystander Apoptosis through gp41

(2010) X. M. Wang et al.   JOURNAL OF VIROLOGY

Immune activation and AIDS pathogenesis

(2009) Donald L Sodora et al.   AIDS

Altered Bystander Apoptosis Induction and Pathogenesis of Enfuvirtide-Resistant HIV Type 1 Env Mutants

(2009) Himanshu Garg et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

New insights on the role of apoptosis and autophagy in HIV pathogenesis

(2009) M.-L. Gougeon et al.   APOPTOSIS

Mitochondrial membrane potential and apoptosis of blood mononuclear cells in untreated HIV-1 infected patients

(2009) T Sternfeld et al.   HIV MEDICINE

Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages

(2009) George B. Kyei et al.   JOURNAL OF CELL BIOLOGY

Kinetics of T lymphocyte apoptosis and the cellular immune response in SIVmac239-infected rhesus macaques

(2009) Mareike Meythaler et al.   JOURNAL OF MEDICAL PRIMATOLOGY

AIDS pathogenesis: a tale of two monkeys

(2009) Guido Silvestri   JOURNAL OF MEDICAL PRIMATOLOGY

Induction of Robust Cellular and Humoral Virus-Specific Adaptive Immune Responses in Human Immunodeficiency Virus-Infected Humanized BLT Mice

(2009) D. M. Brainard et al.   JOURNAL OF VIROLOGY

Differential Role of Autophagy in CD4 T Cells and Macrophages during X4 and R5 HIV-1 Infection

(2009) Lucile Espert et al.   PLoS One

Enhanced CD4+ cellular apoptosis by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with progressive HIV-1 infection

(2009) Jessica Wade et al.   VIROLOGY

Emerging Concepts in the Immunopathogenesis of AIDS

(2008) Daniel C. Douek et al.   Annual Review of Medicine

Role of HIV Gp41 mediated fusion/hemifusion in bystander apoptosis

(2008) H. Garg et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Specific Enfuvirtide‐Associated Mutational Pathways in HIV‐1 Gp41 Are Significantly Correlated With an Increase in CD4+Cell Count, Despite Virological Failure

(2008) Valentina Svicher et al.   JOURNAL OF INFECTIOUS DISEASES

Differential CD4+ T-Lymphocyte Apoptosis and Bystander T-Cell Activation in Rhesus Macaques and Sooty Mangabeys during Acute Simian Immunodeficiency Virus Infection

(2008) M. Meythaler et al.   JOURNAL OF VIROLOGY

Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease

(2008) Steven A McCarroll et al.   NATURE GENETICS

HIV-1 induced activation of CD4+ T cells creates new targets for HIV-1 infection in human lymphoid tissue ex vivo

(2007) A. Biancotto et al.   BLOOD