Transcriptome analysis of genetically matched human induced pluripotent stem cells disomic or trisomic for chromosome 21

Down Syndrome Developmental Brain Transcriptome Reveals Defective Oligodendrocyte Differentiation and Myelination

(2016) Jose Luis Olmos-Serrano et al.   NEURON

Trisomy 21 consistently activates the interferon response

(2016) Kelly D Sullivan et al.   eLife

The fetal brain transcriptome and neonatal behavioral phenotype in the Ts1Cje mouse model of Down syndrome

(2015) Faycal Guedj et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Functional transcriptome analysis of the postnatal brain of the Ts1Cje mouse model for Down syndrome reveals global disruption of interferon-related molecular networks

(2014) King-Hwa Ling et al.   BMC GENOMICS

Transcriptional landscape of repetitive elements in normal and cancer human cells

(2014) Steven W Criscione et al.   BMC GENOMICS

Haematopoietic development and leukaemia in Down syndrome

(2014) Irene Roberts et al.   BRITISH JOURNAL OF HAEMATOLOGY

Domains of genome-wide gene expression dysregulation in Down’s syndrome

(2014) Audrey Letourneau et al.   NATURE

Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells

(2014) Jichang Wang et al.   NATURE

Deep transcriptome profiling of mammalian stem cells supports a regulatory role for retrotransposons in pluripotency maintenance

(2014) Alexandre Fort et al.   NATURE GENETICS

Usp16 contributes to somatic stem-cell defects in Down’s syndrome

(2013) Maddalena Adorno et al.   NATURE

Translating dosage compensation to trisomy 21

(2013) Jun Jiang et al.   NATURE

Pyramidal Neurons Derived from Human Pluripotent Stem Cells Integrate Efficiently into Mouse Brain Circuits In Vivo

(2013) Ira Espuny-Camacho et al.   NEURON

The Subread aligner: fast, accurate and scalable read mapping by seed-and-vote

(2013) Yang Liao et al.   NUCLEIC ACIDS RESEARCH

Deficits in human trisomy 21 iPSCs and neurons

(2013) J. P. Weick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Trisomy Correction in Down Syndrome Induced Pluripotent Stem Cells

(2012) Li B. Li et al.   Cell Stem Cell

Embryonic stem cell potency fluctuates with endogenous retrovirus activity

(2012) Todd S. Macfarlan et al.   NATURE

Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses

(2012) Yichen Shi et al.   NATURE NEUROSCIENCE

HERV-H RNA is abundant in human embryonic stem cells and a precise marker for pluripotency

(2012) Federico A Santoni et al.   Retrovirology

Making cortex in a dish: In vitro corticopoiesis from embryonic stem cells

(2011) Nicolas Gaspard et al.   CELL CYCLE

Mouse Models for Down Syndrome-Associated Developmental Cognitive Disabilities

(2011) Chunhong Liu et al.   DEVELOPMENTAL NEUROSCIENCE

Regulation of the alternative splicing of tau exon 10 by SC35 and Dyrk1A

(2011) W. Qian et al.   NUCLEIC ACIDS RESEARCH

Massive-Scale RNA-Seq Analysis of Non Ribosomal Transcriptome in Human Trisomy 21

(2011) Valerio Costa et al.   PLoS One

Down Syndrome: From Understanding the Neurobiology to Therapy

(2010) K. Gardiner et al.   JOURNAL OF NEUROSCIENCE

Engineering DYRK1A overdosage yields Down syndrome-characteristic cortical splicing aberrations

(2010) Debra Toiber et al.   NEUROBIOLOGY OF DISEASE

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Increased Dosage of Dyrk1A Alters Alternative Splicing Factor (ASF)-regulated Alternative Splicing of Tau in Down Syndrome

(2008) Jianhua Shi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY