Article
Food Science & Technology
Paola Sanchez-Bravo, Angel Abellan, Pedro J. Zapata, Cristina Garcia-Viguera, Raul Dominguez-Perles, Maria Jose Gimenez
Summary: Broccoli has been used to develop healthy beverages by supplementing craft beers with broccoli sprouts and powder, which are rich in bioactive sulforaphane (SFN). The SFN concentrations were high in the supplemented beers (5.00 and 2.54 mg/L for sprouts and powder, respectively) prior to bottling, and decreased by >50% after bottling. After 150 storage days, the SFN concentrations were 1.08 and 0.30 mg/L for sprouts and powder, respectively. Sensory analysis showed positive attributes in beers developed using sprouts, but also negative attributes associated with broccoli-based beer, such as cooked vegetables, alcoholic, and earthy leather flavors. Overall, the addition of fresh broccoli sprouts is more suitable for enhancing SFN content and sensory features in beer, providing a functional alternative appreciated by consumers.
Article
Biotechnology & Applied Microbiology
Korbinian Sinzinger, Doris Schieder, Broder Ruehmann, Volker Sieber
Summary: This study investigates the utilization of biomass from various Nostoc strains, elucidates the complex sugar profiles, and examines the biocompositions and enzymatic saccharification of three exemplary strains. The results demonstrate the difficulty in utilizing the complex heteroglycans in Nostoc biomass, yet also highlight the potential for efficient biomass utilization.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2022)
Article
Biochemistry & Molecular Biology
Yuanyue Zhang, Shengbao Cai, Shuang Ma, Shuai Zhao, Junjie Yi, Linyan Zhou
Summary: This study aimed to investigate the phenolic profiles, antioxidant activities, and alpha-glycosidase inhibitory activities of water caltrop husk. The results showed that tannins were the main constituents, and the free phenolic fraction exhibited the strongest inhibition towards alpha-glycosidase and had good antioxidant activities.
Article
Plant Sciences
Nawal Buzgaia, Soo Yee Lee, Yaya Rukayadi, Faridah Abas, Khozirah Shaari
Summary: The research evaluated the antioxidant and alpha-glucosidase inhibitory activities of the Arbutus genus plant, showing its potential medicinal value in treating diabetes and preventing oxidative damage.
Article
Biochemistry & Molecular Biology
Paulo Gomes, Luis Quiros-Guerrero, Consuelo Silva, Sonia Pamplona, Jean A. Boutin, Marcos Eberlin, Jean-Luc Wolfender, Milton Silva
Summary: Stryphnodendron pulcherrimum, known for its high tannin content, contains various phenolic compounds in its leaf extracts, which show potential pharmaceutical applications.
Article
Food Science & Technology
Estefania J. Carrera, Maria Jesus Cejudo-Bastante, Nelson Hurtado, Francisco J. Heredia, M. Lourdes Gonzalez-Miret
Summary: Colombian purple corn Zea mays L. by-products were chemically characterized after purification and fractionation. Cob and leaves showed a more complete flavonoid profile with higher content of anthocyanins and flavonols compared to grains, resulting in the highest reducing power and radical scavenging activity. The antioxidant fractions corresponded to higher molecular weight compounds. This study provides the first chemical and antioxidant characterization of purple corn by-products, as well as pure fractions of Zea mays L. for various industries.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Biochemistry & Molecular Biology
Gabriel Vargas-Arana, Claudia Merino-Zegarra, angel Martin Rodriguez del-Castillo, Cristina Quispe, Ezequiel Viveros-Valdez, Mario J. Simirgiotis
Summary: In this study, nine natural populations of ungurahui from the Peruvian Amazon were analyzed for their nutritional and biological activities. UHPLC-MS analysis revealed the presence of 24 compounds with antioxidant and cholinesterase inhibition activities. The differences among populations may be attributed to the different growing conditions of ungurahui. The fruit of the ungurahui palm tree is a good natural source of antioxidants and dietary fatty acids, which can be used for the prevention of neurodegenerative or related non-chronic transmittable diseases.
Article
Food Science & Technology
Xiuqing Zheng, Hai Chi, Shuang Ma, Lei Zhao, Shengbao Cai
Summary: The aim of this study was to identify and investigate novel peptides in rice wine that have high α-glucosidase inhibition and antioxidant activities. Peptide composition, α-glucosidase inhibition, and antioxidant activities were studied for different elution fractions obtained from macroporous resin adsorption chromatography. In silico analyses and in vitro experiments were used to screen and validate potentially bioactive peptides, and molecular docking and molecular dynamics simulations were used to understand their mechanisms. Results showed that peptides from 50% ethanol-eluted rice wine exhibited strong α-glucosidase inhibition and antioxidant activities. Three novel peptides, SSLFR, QFTPR, and FTYPR, showed good α-glucosidase inhibition and antioxidant activities, with FTYPR exhibiting the best bioactivities. These peptides could bind to ABTS and DPPH radicals and the active site of α-glucosidase through hydrogen bonding, Pi bonding, and van der Waals forces. This study not only provides new knowledge about the health effects of rice wine but also offers theoretical foundations for the development of health products to enhance its economic value.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Chemistry, Applied
Hui Wang, Lili Hu, Xiaotu Chang, Yuge Hu, Yan Zhang, Peng Zhou, Xiaojiao Cui
Summary: A method using UHPLC-MS/MS was developed for the determination of toxoflavin and fervenulin in 6 types of food, and the degradation products were identified.
Article
Biochemistry & Molecular Biology
Maria Campillo, Sonia Medina, Federico Fanti, Juana I. Gallego-Gomez, Agustin Simonelli-Munoz, Valerie Bultel-Ponce, Thierry Durand, Jean Marie Galano, Francisco A. Tomas-Barberan, Angel Gil-Izquierdo, Raul Dominguez-Perles
Summary: The study demonstrates the potential of plant oxylipins in modulating inflammatory processes and protecting cells from inflammation, suggesting that specific plant oxylipins can prevent inflammatory events.
FREE RADICAL BIOLOGY AND MEDICINE
(2021)
Article
Chemistry, Applied
Jiaxin Wang, Xuening Lu, Jiaen Zhang, Zeheng Xiao
Summary: Lipids including PC, PE, SM, and LPC were extracted from golden apple snails, with SM being the most abundant lipid. The ethanol/hexane extraction method from GAS proved effective and time-saving, showing potential for controlling the snail invasion.
Article
Chemistry, Applied
Mariana Rodrigues da Silva, Felipe Sanchez Bragagnolo, Renato Lajarim Carneiro, Isabela de Oliveira Carvalho Pereira, Jose Antonio Aquino Ribeiro, Clenilson Martins Rodrigues, Rebecca E. Jelley, Bruno Fedrizzi, Cristiano Soleo Funari
Summary: This study conducted a comprehensive chemical investigation of coffee by-products, identifying a variety of bioactive compounds. Some compounds in the by-products even showed higher content than coffee beans, indicating potential economic and environmental benefits that can be explored.
Article
Chemistry, Applied
Tian-Long Wang, Yi-Cong Li, Chun-Sheng Lin, Yi-Ping Zou
Summary: Here, we report a method for simultaneous baseline separation and detection of sugars using UHPLC-ESIMS, and demonstrate its comprehensive and effective application in qualitative and quantitative analysis of polysaccharides in TCMs.
CARBOHYDRATE POLYMERS
(2022)
Article
Biochemical Research Methods
Long-Hui Liang, Xi Cheng, Hui-Lan Yu, Yang Yang, Xi-Hui Mu, Bo Chen, Xiao-Sen Li, Ji-Na Wu, Long Yan, Chang-Cai Liu, Shi-Lei Liu
Summary: This study introduces a novel method for the quantitative detection of ricin in beverages using isotope-labeled internal standard mass spectrometry. The method allows for rapid and accurate detection of ricin in beverages, while also providing a new strategy for investigating the illegal use of ricin in chemical weapons.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2021)
Article
Food Science & Technology
Shuang Ma, Xiuqing Zheng, Yuanyue Zhang, Shuai Zhao, Junjie Yi, Shengbao Cai
Summary: This study investigated the polyphenolic components and tyrosinase activation activity of different extracts from the seed shell of Prinsepia utilis. The major polyphenolic compounds were (+)-catechin and (-)-epicatechin, which exhibited tyrosinase activation activity by acting as substrates. Molecular docking and dynamics simulation studies showed that (+)-catechin and (-)-epicatechin could stably bind to the tyrosinase active site through various forces. These findings not only provide a scientific basis for the potential use of P. utilis seed shell as a tyrosinase activator, but also contribute to the high value utilization of P. utilis processing by-products.
Review
Food Science & Technology
Mohamad Fawzi Mahomoodally, Dilmar Aniisah Sanaa, Gokhan Zengin, Monica Gallo, Domenico Montesano
Summary: This study systematically reviewed scientific literature from the past 10 years and highlighted the therapeutic uses of marine animals and animal products globally. It was found that a single aquatic animal could be used for treating multiple ailments, while an ailment could be addressed by several marine animals and animal-derived products. However, there is a lack of validated pharmacological studies to support these traditional uses.
FOOD REVIEWS INTERNATIONAL
(2023)
Review
Food Science & Technology
Naoufal E. L. Hachlafi, Tariq Aanniz, Naoual El Menyiy, Aicha El Baaboua, Nasreddine El Omari, Abdelaali Balahbib, Mohammad Ali Shariati, Gokhan Zengin, Kawtar Fikri-Benbrahim, Abdelhakim Bouyahya
Summary: Camphene, a volatile compound found in various aromatic and medicinal plants, has shown multiple biological activities. This review summarizes its biological properties, mechanisms of action, and potential applications as a drug. Further research is needed to validate its use in the pharmaceutical field.
FOOD REVIEWS INTERNATIONAL
(2023)
Review
Food Science & Technology
Mohammed Saber, Naoual El Menyiy, Saoulajan Charfi, Hanae Naceiri Mrabti, Omar Belmehdi, Hamza El Moudden, Douae Taha, Nasreddine El Omari, Abdelaali Balahbib, Gokhan Zengin, Mohamed Bakha, Mohamed Tabyaoui, Hicham Harhar, Monica Gallo, Domenico Montesano, Abdelhakim Bouyahya
Summary: This article reports previous investigations on Tetraclinis articulata, including its taxonomy, distribution, traditional use, phytochemistry, biological effects, toxicology, nutritional value, and economic interest. The plant exhibits various biological activities and shows no toxicity. However, further research is needed to validate its pharmacological use and toxicity.
FOOD REVIEWS INTERNATIONAL
(2023)
Review
Food Science & Technology
Maksim Rebezov, Muhammad Usman Khan, Abdelhakim Bouyahya, Muhammad Imran, Tabussam Tufail, Olga Loretts, Olga Neverova, Svetlana Artyukhova, Elena Kuznetsova, Vladimir Ermolaev, Abdelaali Balahbib, Muthu Thiruvengadam, Gokhan Zengin, Mohammad Ali Shariati
Summary: Tiger nuts are a nutritional plant with tubers rich in vegetable oils and other beneficial compounds. Tiger nut oil is underutilized in the food industry, but its dietary fibers can be used to prepare fiber-rich meat products. Tiger nuts and their by-products have potential applications in the food industry, pharmaceuticals, agricultural development, and biofuel production.
FOOD REVIEWS INTERNATIONAL
(2023)
Review
Biotechnology & Applied Microbiology
Nabeelah Bibi Sadeer, Gokhan Zengin, Mohamad Fawzi Mahomoodally
Summary: Mangrove plants are ecologically important and produce unique compounds in extreme conditions. Mangrove microbes have the potential for vaccine development and the synthesis of nanoparticles. Mangrove plants also contain bioactive compounds with pharmaceutical applications.
CRITICAL REVIEWS IN BIOTECHNOLOGY
(2023)
Review
Food Science & Technology
Sabira Sultana, Abdelhakim Bouyahya, Maksim Rebezov, Mohammad Ali Shariati, Abdelaali Balahbib, Aya Khouchlaa, Ouadie Mohamed El Yaagoubi, Adnan Khaliq, Nasreddine El Omari, Saad Bakrim, Gokhan Zengin, Muhammad Akram, Mars Khayrullin, Irina Bogonosova, Shafi Mahmud, Jesus Simal-Gandara
Summary: For individuals living with progressive cancer, nutritional therapy and exercise are important factors in improving health and quality of life. Cancer survivors and patients are encouraged to seek knowledge on diet, exercise, and supplements to maintain treatment outcomes, living quality, and survival. A healthy diet plays a significant role in cancer treatment.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Plant Sciences
Gulderen Yilmaz, Nuraniye Eruygur, Gulnur Eksi Bona, Mehmet Bona, Mehmet Akdeniz, Mustafa Abdullah Yilmaz, Abdulselam Ertas
Summary: In this study, the methanol extracts of five Salvia taxa were investigated for their antioxidant activity and enzyme inhibitory potentials. The S. aytachii extract showed the highest total phenolic and flavonoid contents, suggesting its potential for further phytochemical research.
SOUTH AFRICAN JOURNAL OF BOTANY
(2023)
Article
Biochemistry & Molecular Biology
Simon Vlad Luca, Gokhan Zengin, Kouadio Ibrahime Sinan, Krystyna Skalicka-Wozniak, Adriana Trifan
Summary: This study characterized and assessed the phytochemicals and biological activities of the essential oils and extracts of three Lamiaceae species. The results showed that they are rich in bioactive metabolites with antioxidant and enzyme inhibitory properties.
Article
Biochemistry & Molecular Biology
Gokhan Zengin, Alvaro Fernandez-Ochoa, Maria de la Luz Cadiz-Gurrea, Francisco Javier Leyva-Jimenez, Antonio Segura-Carretero, Fevzi Elbasan, Evren Yildiztugay, Sumira Malik, Asaad Khalid, Ashraf N. Abdalla, Mohamad Fawzi Mahomoodally
Summary: This study investigated the phytochemical profile and biological properties of Paliurus spina-christi Mill., a medicinal plant traditionally used for various human ailments. The methanol extract exhibited the strongest antioxidant and anti-tyrosinase activities. These findings contribute to the understanding of P. spina-christi as a potential source of naturally occurring bioactive compounds with biomedical applications.
Article
Chemistry, Analytical
Gokhan Zengin, Adriano Mollica, Jelena Arsenijevic, Branimir Pavlic, Zoran Zekovic, Kouadio Ibrahime Sinan, Linlin Yan, Aleksandra Cvetanovic Kljakic, Slavica Razic
Summary: In this study, traditional and modern separation techniques such as hydrodistillation and supercritical fluid extraction were utilized to efficiently extract high-value compounds from chamomile. GC analysis revealed that oxygenated sesquiterpenes and non-terpene compounds were the dominant components, with alpha-bisabolol oxide A and alpha-bisabolol oxide B being the most abundant individual compounds. The biological potential of the essential oils and extracts showed that the essential oils had better antioxidant activity, while the extracts exhibited better inhibition of the tested enzymes. Molecular docking experiments identified alpha-bisabolol oxide B as having higher affinity for tyrosinase.
Article
Biochemistry & Molecular Biology
Hasan Karagecili, Mustafa Abdullah Yilmaz, Adem Erturk, Hatice Kiziltas, Leyla Guven, Saleh H. Alwasel, Ilhami Gulcin
Summary: This study investigated the chemical composition and antioxidant activities of propolis, finding that it is rich in phenolic and flavonoid compounds with antioxidant, antimicrobial, and anticancer properties. Propolis extract also exhibited inhibitory activities against enzymes associated with diabetes, Alzheimer's disease, and glaucoma. Additionally, twenty-eight phenolic compounds were determined to be major organic compounds in propolis, making it a potential natural product for the treatment of various diseases.
Article
Food Science & Technology
Mehmet Emin Aydemir, Kasim Takim, Mustafa Abdullah Yilmaz
Summary: This research aims to identify the phytochemical constituents of black tea samples from different regions and investigate the impact of brewing time on tea quality. The study found that Turkish and Iranian tea had the richest phytochemical content and highest antioxidant activity. Prolonged brewing time improved the quality of tea, but also led to a stronger release of flavonoids.
FOOD SCIENCE & NUTRITION
(2023)
Review
Microbiology
Yusufjon Gafforov, Milena Raseta, Sylvie Rapior, Manzura Yarasheva, Xuewei Wang, Liwei Zhou, Wan Abd Al Qadr Imad Wan-Mohtar, Muhammad Zafar, Young Woon Lim, Mengcen Wang, Bekhzod Abdullaev, Rainer W. Bussmann, Gokhan Zengin, Jiajia Chen
Summary: Interest in edible and medicinal macrofungi has a long history in Central Asia, while interest in inedible and medicinal macrofungi has recently increased. A study conducted in Uzbekistan collected various species of edible and inedible medicinal basidiomycetes. The research focused on measuring diversity and habitat associations using morphological characters and rDNA-Internal Transcribed Spacer sequence data. The study identified 17 species of medicinal macrofungi associated with 23 species of trees and shrubs. The findings provide valuable information on the traditional and modern uses of these mushrooms, including their potential application as medicines, food, and cosmetic ingredients.
Article
Chemistry, Medicinal
Sabrina Lekmine, Ouided Benslama, Kenza Kadi, Antonio Ignacio Martin-Garcia, Mustafa Abdullah Yilmaz, Salah Akkal, Ali Boumegoura, Abdullah S. Alhomida, Mohammad Shamsul Ola, Ahmad Ali
Summary: This study aimed to investigate the chemical composition and antidiabetic properties of cultivated Hyoscyamus albus L. In the in vitro antidiabetic experiment, the extract from H. albus L. exhibited a higher inhibitory effect on alpha-amylase compared to alpha-glucosidase. Furthermore, the plant extract effectively reduced the levels of cholesterol and triglycerides, suggesting its potential for managing hyperlipidemia.
Article
Plant Sciences
Engin Tilkat, Veysel Suzerer, Hilal Surmus Asan, Abdulselam Erta, Mustafa Abdullah Yilmaz, Elif Demir, Ayse Hoser, Ahmet Onay
Summary: This study successfully established optimized callus cultures from the leaves and roots of the mastic tree and found that using elicitors can enhance the biosynthesis of anticancer triterpenoids.
SOUTH AFRICAN JOURNAL OF BOTANY
(2023)
Article
Plant Sciences
Vinayak Nayak, Sushmita Patra, Shrushti Rout, Atala Bihari Jena, Rohit Sharma, Kali Prasad Pattanaik, Jay Singh, Shyam S. Pandey, Ravindra Pratap Singh, Sanatan Majhi, Kshitij R. B. Singh, Rout George Kerry
Summary: This study introduces a customized engineering and designing approach for novel nanotherapeutics, which involves the use of polymeric nanoparticles loaded with specific phytocompounds and coated with an antibody targeting the transferrin receptor. This approach aims to effectively tackle AD-related neuroinflammation by crossing the Blood-Brain Barrier and interacting with target molecules within the brain.
Article
Plant Sciences
Zhi Shang, Yating Gao, Yan Xue, Congcong Zhang, Jiahao Qiu, Yihan Qian, Miao Fang, Xin Zhang, Xuehua Sun, Xiaoni Kong, Yueqiu Gao
Summary: This study investigated the mechanism of Shenge Formula (SGF) in the treatment of nonalcoholic fatty liver disease (NAFLD) using proteomics strategy. The results revealed that SGF could regulate the lipid metabolism and energy consumption process of hepatocytes to treat NAFLD.
Article
Plant Sciences
Long You, Ting Shen, Weicheng Hu, Jae Youl Cho
Summary: By activating growth factor receptors such as EGFR and HER2, protopanaxatriol (PPT) can regulate skin moisturizing factors and multiple signaling pathways, thereby protecting and moisturizing the skin.
Article
Plant Sciences
Lingmei Li, Lei Li, Ce Cao, Fan Guo, Aoao Wang, Li Lin, Zixin Liu, Hongxu Meng, Peng Zhang, Gaojie Xin, Jianxun Liu, Junguo Ren, Jianhua Fu
Summary: The study found that Shuangshen Ningxin Capsule (SSNX) has a protective effect against myocardial ischemia-reperfusion injury. It works by correcting abnormal myocardial energy metabolism, changing the levels and distribution patterns of phospholipids, and stabilizing the structure of the myocardial cell membrane. Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) can be used to detect the spatial distribution of small molecule metabolites in the myocardium.
Article
Plant Sciences
Nidhi Sharma, Ramakrishna Sistla, Sai Balaji Andugulapati
Summary: The study investigates the anti-fibrotic activity of Yohimbine hydrochloride (YHC) in chronic liver injury. The results show that YHC can reduce inflammation and fibrosis, potentially making it a potential lead compound for liver fibrosis treatment.
Article
Plant Sciences
Tao-tao Wang, Cheng-yong Yang, Li Peng, Li Li, Nan-ting Chen, Xue Feng, Jing Xie, Ting-chun Wu, Tao Xu, Yun-zhi Chen
Summary: QSYQ has been found to have an anti-atherosclerotic effect by targeting TTC39B-LXR mediated reverse cholesterol transport in the liver. QSYQ not only promotes reverse cholesterol transport, but also improves fatty liver and protects liver function.
Article
Plant Sciences
Zhuo Liu, Yuli Geng, Yanjing Huang, Runan Hu, Fan Li, Jiahui Ding, Wenwen Ma, Haoxu Dong, Kunkun Song, Xiaohu Xu, Xiao Wu, Yufan Song, Mingmin Zhang
Summary: This study investigated the therapeutic efficacy of the Bushen Antai recipe (BAR) in abortion-prone mice and explored its potential mechanisms related to myeloid-derived suppressor cells (MDSCs). The results showed that BAR improved embryo absorption rate and increased the number of MDSCs, promoting normal pregnancy processes.
Article
Plant Sciences
Xue-Ping Yang, Jia-Hua Huang, Fan-Long Ye, Qing-Yun Yv, Sheng Chen, Wen-Wei Li, Min Zhu
Summary: This study found that ECH exerts neuroprotective effects on Parkinson's disease (PD) by regulating the expression of the TLR2/NF-kappa B/NLRP3 axis and reducing the expression of alpha-syn.
Article
Plant Sciences
Lihui Qian, Sirui Huang, Xiaoli Liu, Yongxia Jiang, Yongqu Jiang, Yue Hu, Zhou Yang
Summary: This study highlights the potential use of morroniside in treating post-stroke depression (PSD) by activating the MiR-409-3p-mediated BDNF/TrkB signaling pathway.
Article
Plant Sciences
Jiahui Wu, Hoi Lam Zhang, Suisui Guo, Xin Li, Tingxia Dong, Yue Zhu, Karl Wah Keung Tsim
Summary: This study revealed the significant MDR-preventing effects of Acori Tatarinowii Rhizoma (ATR) in fluoxetine-induced Escherichia coli (E. coli). ATR reduced the accumulation of fluoxetine in bacteria and reversed the fluoxetine-induced membrane damage and superoxide response. The polysaccharide fraction of ATR exhibited the most significant anti-MDR activity.
Article
Plant Sciences
Chao-Sheng Lu, Chen-Yu Wu, Yi-Hong Wang, Qing-Qing Hu, Rong-Yue Sun, Min-Jie Pan, Xin-Yu Lu, Ting Zhu, Shuang Luo, Hong-Jing Yang, Dan Wang, Hong-Wei Wang
Summary: This study demonstrates the potential of icariin in alleviating testicular dysfunction induced by T1D, with the involvement of AMPK-mediated Nrf2 activation and NF-kappa B p65 inhibition.
Article
Plant Sciences
Hongkang Zhu, Fanglin Shen, Xiaochen Wang, He Qian, Yu Liu
Summary: This study explores the therapeutic effect and underlying mechanism of chlorogenic acid (CGA) in alleviating sleep deprivation-induced cognitive deficits and neuroinflammation. By interacting with the gut microbiota, CGA improves intestinal barrier, regulates immune function, and enhances hippocampal-dependent spatial memory via Nrf2/PPAR signaling pathways. This research provides important insights into the clinical application of CGA in sleep-related disorders.
Article
Plant Sciences
Meng Liu, Pengli Guo, Mengnan Zeng, Yuhan Zhang, Jufang Jia, Yanling Liu, Xu Chen, Haixue Kuang, Weisheng Feng, Xiaoke Zheng
Summary: This study found that Fre D and Reh C improved S-AKI through the ER-TLR4-IL-1β pathway, and ERα and ERβ may have direct or indirect interactions with TLR4.
Review
Plant Sciences
Puja Ghosh, Niloy Patari, Chennu Manisha, Duraiswamy Basavan, Velammal Petchiappan, Antony Justin
Summary: This article reviews the possible mechanisms of alternative treatment using lectins for cancer, particularly MDRC cancer. Lectins have the ability to reverse drug resistance mechanisms and show synergistic effects when combined with complementary medicine. They can also serve as nano drug carriers for targeted delivery.
Article
Plant Sciences
Tian Lan, Xiao-juan Geng, Si-jia Zhang, Xi-xi Zeng, Jun-jie Ying, Yi Xu, Shi-yu Liu, Ping Li, Yu-hua Tong, Wen Wang, Zhu-jun Mao, Si-wei Wang
Summary: This study investigates the impact of SNS on MAFLD in mice and explores its underlying molecular mechanisms. The results show that SNS effectively reduces lipid accumulation and improves MAFLD through the activation of AMPK and the modulation of lipid metabolism-related proteins.
