Shenge Formula attenuates high-fat diet-induced obesity and fatty liver via inhibiting ACOX1

Ban-xia-xie-xin-tang ameliorates hepatic steatosis by regulating Cidea and Cidec expression in HFD-fed mice

(2022) Qing-song Xia et al.   PHYTOMEDICINE

Discovery of a potent allosteric activator of DGKQ that ameliorates obesity-induced insulin resistance via the sn-1,2-DAG-PKCε signaling axis

(2022) Zu-Guo Zheng et al.   Cell Metabolism

Si Miao Formula attenuates non-alcoholic fatty liver disease by modulating hepatic lipid metabolism and gut microbiota

(2021) Ruiting Han et al.   PHYTOMEDICINE

The complex link between NAFLD and type 2 diabetes mellitus — mechanisms and treatments

(2021) Giovanni Targher et al.   Nature Reviews Gastroenterology & Hepatology

Metabolism and antioxidation regulation of total flavanones from Sedum sarmentosum Bunge against high-fat diet-induced fatty liver disease in Nile tilapia (Oreochromis niloticus)

(2021) Kai Yu et al.   FISH PHYSIOLOGY AND BIOCHEMISTRY

CPT1A-mediated Fat Oxidation, Mechanisms, and Therapeutic Potential

(2020) Isabel R Schlaepfer et al.   ENDOCRINOLOGY

Metabolic interactions between peroxisomes and mitochondria with a special focus on acylcarnitine metabolism

(2020) Sander M. Houten et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Acetyl-CoA Derived from Hepatic Peroxisomal β-Oxidation Inhibits Autophagy and Promotes Steatosis via mTORC1 Activation

(2020) Anyuan He et al.   MOLECULAR CELL

Liver CPT1A gene therapy reduces diet-induced hepatic steatosis in mice and highlights potential lipid biomarkers for human NAFLD

(2020) Minéia Weber et al.   FASEB JOURNAL

Peroxisomal oxidation of erucic acid suppresses mitochondrial fatty acid oxidation by stimulating malonyl-CoA formation in the rat liver

(2020) Xiaocui Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Global epidemiology of NAFLD-related HCC: trends, predictions, risk factors and prevention

(2020) Daniel Q. Huang et al.   Nature Reviews Gastroenterology & Hepatology

Puerarin protects against high‐fat high‐sucrose diet‐induced non‐alcoholic fatty liver disease by modulating PARP‐1/PI3K/AKT signaling pathway and facilitating mitochondrial homeostasis

(2019) Shuai Wang et al.   PHYTOTHERAPY RESEARCH

BabaoDan attenuates high-fat diet-induced non-alcoholic fatty liver disease via activation of AMPK signaling

(2019) Dandan Sheng et al.   Cell and Bioscience

Molecular actions of PPARα in lipid metabolism and inflammation

(2018) Nadia Bougarne et al.   ENDOCRINE REVIEWS

Specific Inhibition of Acyl-CoA Oxidase-1 by an Acetylenic Acid Improves Hepatic Lipid and Reactive Oxygen Species (ROS) Metabolism in Rats Fed a High Fat Diet

(2017) Jia Zeng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Herbal medicines and nonalcoholic fatty liver disease

(2016) Hong Yao et al.   WORLD JOURNAL OF GASTROENTEROLOGY

PPARα-Deficient ob/ob Obese Mice Become More Obese and Manifest Severe Hepatic Steatosis Due to Decreased Fatty Acid Oxidation

(2015) Qian Gao et al.   AMERICAN JOURNAL OF PATHOLOGY

Molecular mechanism of PPARα action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease

(2015) Michal Pawlak et al.   JOURNAL OF HEPATOLOGY

Peroxisomes: A Nexus for Lipid Metabolism and Cellular Signaling

(2014) Irfan J. Lodhi et al.   Cell Metabolism

Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin

(2013) Morgan D Fullerton et al.   NATURE MEDICINE

Comparative Analysis of Sample Preparation Methods To Handle the Complexity of the Blood Fluid Metabolome: When Less Is More

(2012) Sara Tulipani et al.   ANALYTICAL CHEMISTRY

Progressive Endoplasmic Reticulum Stress Contributes to Hepatocarcinogenesis in Fatty Acyl-CoA Oxidase 1–Deficient Mice

(2011) Jiansheng Huang et al.   AMERICAN JOURNAL OF PATHOLOGY

Sustained activation of PPARα by endogenous ligands increases hepatic fatty acid oxidation and prevents obesity in ob/ob mice

(2011) Jiansheng Huang et al.   FASEB JOURNAL

Molecular therapy for obesity and diabetes based on a long-term increase in hepatic fatty-acid oxidation

(2010) Josep M. Orellana-Gavaldà et al.   HEPATOLOGY

Identification of a Physiologically Relevant Endogenous Ligand for PPARα in Liver

(2009) Manu V. Chakravarthy et al.   CELL