Targeting the PXR–TLR4 signaling pathway to reduce intestinal inflammation in an experimental model of necrotizing enterocolitis

Gut bacteria dysbiosis and necrotising enterocolitis in very low birthweight infants: a prospective case-control study

(2016) Barbara B Warner et al.   LANCET

Pregnane X Receptor Regulates Pathogen-Induced Inflammation and Host Defense against an Intracellular Bacterial Infection through Toll-like Receptor 4

(2016) Zhijuan Qiu et al.   Scientific Reports

Functional Intestinal Bile Acid 7α-Dehydroxylation by Clostridium scindens Associated with Protection from Clostridium difficile Infection in a Gnotobiotic Mouse Model

(2016) Nicolas Studer et al.   Frontiers in Cellular and Infection Microbiology

Breast milk protects against the development of necrotizing enterocolitis through inhibition of Toll-like receptor 4 in the intestinal epithelium via activation of the epidermal growth factor receptor

(2015) M Good et al.   Mucosal Immunology

Symbiotic Bacterial Metabolites Regulate Gastrointestinal Barrier Function via the Xenobiotic Sensor PXR and Toll-like Receptor 4

(2014) Madhukumar Venkatesh et al.   IMMUNITY

Reciprocal Expression and Signaling of TLR4 and TLR9 in the Pathogenesis and Treatment of Necrotizing Enterocolitis

(2014) S. C. Gribar et al.   JOURNAL OF IMMUNOLOGY

A small intestinal organoid model of non-invasive enteric pathogen–epithelial cell interactions

(2014) S S Wilson et al.   Mucosal Immunology

A Critical Role for TLR4 Induction of Autophagy in the Regulation of Enterocyte Migration and the Pathogenesis of Necrotizing Enterocolitis

(2013) M. D. Neal et al.   JOURNAL OF IMMUNOLOGY

Loss of TLR2 Worsens Spontaneous Colitis in MDR1A Deficiency through Commensally Induced Pyroptosis

(2013) B. Ey et al.   JOURNAL OF IMMUNOLOGY

Intestinal Epithelial Toll-Like Receptor 4 Regulates Goblet Cell Development and Is Required for Necrotizing Enterocolitis in Mice

(2012) Chhinder P. Sodhi et al.   GASTROENTEROLOGY

Toll-like Receptor 4 Is Expressed on Intestinal Stem Cells and Regulates Their Proliferation and Apoptosis via the p53 Up-regulated Modulator of Apoptosis

(2012) Matthew D. Neal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Worms, flies and four-legged friends: the applicability of biological models to the understanding of intestinal inflammatory diseases

(2011) J. Lin et al.   Disease Models & Mechanisms

Pregnane X receptor activation induces FGF19-dependent tumor aggressiveness in humans and mice

(2011) Hongwei Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Necrotizing Enterocolitis

(2011) Josef Neu et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Mechanism of Excessive Intestinal Inflammation in Necrotizing Enterocolitis: An Immature Innate Immune Response

(2011) Nanda Nanthakumar et al.   PLoS One

Fecal Microbiota in Premature Infants Prior to Necrotizing Enterocolitis

(2011) Volker Mai et al.   PLoS One

Toll-Like Receptor-4 Inhibits Enterocyte Proliferation via Impaired β-Catenin Signaling in Necrotizing Enterocolitis

(2009) Chhinder P. Sodhi et al.   GASTROENTEROLOGY

Mortality of necrotizing enterocolitis expressed by birth weight categories

(2009) Shimae Cross Fitzgibbons et al.   JOURNAL OF PEDIATRIC SURGERY