Functional Intestinal Bile Acid 7α-Dehydroxylation by Clostridium scindens Associated with Protection from Clostridium difficile Infection in a Gnotobiotic Mouse Model

Ursodeoxycholic Acid Inhibits Clostridium difficile Spore Germination and Vegetative Growth, and Prevents the Recurrence of Ileal Pouchitis Associated With the Infection

(2016) Alexa R. Weingarden et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Genome-guided design of a defined mouse microbiota that confers colonization resistance against Salmonella enterica serovar Typhimurium

(2016) Sandrine Brugiroux et al.   Nature Microbiology

The Mouse Intestinal Bacterial Collection (miBC) provides host-specific insight into cultured diversity and functional potential of the gut microbiota

(2016) Ilias Lagkouvardos et al.   Nature Microbiology

Antibiotic-Induced Alterations of the Gut Microbiota Alter Secondary Bile Acid Production and Allow for Clostridium difficile Spore Germination and Outgrowth in the Large Intestine

(2016) Casey M. Theriot et al.   mSphere

Changes in Colonic Bile Acid Composition following Fecal Microbiota Transplantation Are Sufficient to Control Clostridium difficile Germination and Growth

(2016) Alexa R. Weingarden et al.   PLoS One

A biosynthetic pathway for a prominent class of microbiota-derived bile acids

(2015) A Sloan Devlin et al.   Nature Chemical Biology

The outer mucus layer hosts a distinct intestinal microbial niche

(2015) Hai Li et al.   Nature Communications

Identification of a Novel Lipoprotein Regulator of Clostridium difficile Spore Germination

(2015) Kelly A. Fimlaid et al.   PLoS Pathogens

Effects of Vendor and Genetic Background on the Composition of the Fecal Microbiota of Inbred Mice

(2015) Aaron C. Ericsson et al.   PLoS One

Variation in Taxonomic Composition of the Fecal Microbiota in an Inbred Mouse Strain across Individuals and Time

(2015) Yana Emmy Hoy et al.   PLoS One

Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile

(2014) Charlie G. Buffie et al.   NATURE

Beyond intestinal soap—bile acids in metabolic control

(2014) Folkert Kuipers et al.   Nature Reviews Endocrinology

Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection

(2014) Casey M. Theriot et al.   Nature Communications

Functional divergence in gastrointestinal microbiota in physically-separated genetically identical mice

(2014) G. B. Rogers et al.   Scientific Reports

Microbiota transplantation restores normal fecal bile acid composition in recurrent Clostridium difficile infection

(2013) Alexa R. Weingarden et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Microbiota-liberated host sugars facilitate post-antibiotic expansion of enteric pathogens

(2013) Katharine M. Ng et al.   NATURE

Muricholic Acids Inhibit Clostridium difficile Spore Germination and Growth

(2013) Michael B. Francis et al.   PLoS One

Bile Acid Recognition by the Clostridium difficile Germinant Receptor, CspC, Is Important for Establishing Infection

(2013) Michael B. Francis et al.   PLoS Pathogens

Dysfunction of Organic Anion Transporting Polypeptide 1a1 Alters Intestinal Bacteria and Bile Acid Metabolism in Mice

(2012) Youcai Zhang et al.   PLoS One

Bile acids in the colon, from healthy to cytotoxic molecules

(2012) Juan I. Barrasa et al.   TOXICOLOGY IN VITRO

Interaction between the intestinal microbiota and host in Clostridium difficile colonization resistance

(2012) Robert A. Britton et al.   TRENDS IN MICROBIOLOGY

Targeted Restoration of the Intestinal Microbiota with a Simple, Defined Bacteriotherapy Resolves Relapsing Clostridium difficile Disease in Mice

(2012) Trevor D. Lawley et al.   PLoS Pathogens

Effect of Antibiotic Treatment on the Intestinal Metabolome

(2011) L. Caetano M. Antunes et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Profound Alterations of Intestinal Microbiota following a Single Dose of Clindamycin Results in Sustained Susceptibility to Clostridium difficile-Induced Colitis

(2011) Charlie G. Buffie et al.   INFECTION AND IMMUNITY

Reconsidering the Sporulation Characteristics of Hypervirulent Clostridium difficile BI/NAP1/027

(2011) David A. Burns et al.   PLoS One

Dose-Response of Five Bile Acids on Serum and Liver Bile Acid Concentrations and Hepatotoxicty in Mice

(2011) Peizhen Song et al.   TOXICOLOGICAL SCIENCES

Inhibiting the Initiation of Clostridium difficile Spore Germination using Analogs of Chenodeoxycholic Acid, a Bile Acid

(2010) J. A. Sorg et al.   JOURNAL OF BACTERIOLOGY

Murine Model ofClostridium difficileInfection with Aged Gnotobiotic C57BL/6 Mice and a BI/NAP1 Strain

(2010) S. W. Pawlowski et al.   JOURNAL OF INFECTIOUS DISEASES

The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments

(2009) S. A. Bustin et al.   CLINICAL CHEMISTRY

The enterohepatic circulation of bile acids in mammals: form and functions

(2009) Alan et al.   Frontiers in Bioscience-Landmark

Bile acids: regulation of synthesis

(2009) John Y. L. Chiang   JOURNAL OF LIPID RESEARCH

Clostridium difficile infection: new developments in epidemiology and pathogenesis

(2009) Maja Rupnik et al.   NATURE REVIEWS MICROBIOLOGY

Bile Salts and Glycine as Cogerminants for Clostridium difficile Spores

(2008) J. A. Sorg et al.   JOURNAL OF BACTERIOLOGY