A small intestinal organoid model of non-invasive enteric pathogen–epithelial cell interactions

The Cytosolic Bacterial Peptidoglycan Sensor Nod2 Affords Stem Cell Protection and Links Microbes to Gut Epithelial Regeneration

(2014) Giulia Nigro et al.   Cell Host & Microbe

Paneth Cells: Maestros of the Small Intestinal Crypts

(2013) Hans C. Clevers et al.   Annual Review of Physiology

Mouse Paneth cell antimicrobial function is independent of Nod2

(2013) Michael T Shanahan et al.   GUT

Generation of BAC Transgenic Epithelial Organoids

(2013) Gerald Schwank et al.   PLoS One

Growing Self-Organizing Mini-Guts from a Single Intestinal Stem Cell: Mechanism and Applications

(2013) T. Sato et al.   SCIENCE

Probiotic and postbiotic activity in health and disease: comparison on a novel polarised ex-vivo organ culture model

(2012) Katerina Tsilingiri et al.   GUT

Critical Determinants of Human α-Defensin 5 Activity against Non-enveloped Viruses

(2012) Anshu P. Gounder et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alternative Luminal Activation Mechanisms for Paneth Cell α-Defensins

(2012) Jennifer R. Mastroianni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peyer's Patch M Cells Derived from Lgr5+ Stem Cells Require SpiB and Are Induced by RankL in Cultured "Miniguts"

(2012) W. de Lau et al.   MOLECULAR AND CELLULAR BIOLOGY

Wnt5a Potentiates TGF-  Signaling to Promote Colonic Crypt Regeneration After Tissue Injury

(2012) H. Miyoshi et al.   SCIENCE

Host genetic susceptibility, dysbiosis, and viral triggers in inflammatory bowel disease

(2011) Lulu Sun et al.   CURRENT OPINION IN GASTROENTEROLOGY

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

(2011) Toshiro Sato et al.   GASTROENTEROLOGY

α-Defensins in human innate immunity

(2011) Robert I. Lehrer et al.   IMMUNOLOGICAL REVIEWS

Controlled gene expression in primary Lgr5 organoid cultures

(2011) Bon-Kyoung Koo et al.   NATURE METHODS

Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis

(2011) Charles L. Bevins et al.   NATURE REVIEWS MICROBIOLOGY

Regulation of phenotypic heterogeneity permits Salmonella evasion of the host caspase-1 inflammatory response

(2011) M. K. Stewart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Strain-Specific Polymorphisms in Paneth Cell α-Defensins of C57BL/6 Mice and Evidence of Vestigial Myeloid α-Defensin Pseudogenes

(2010) Michael T. Shanahan et al.   INFECTION AND IMMUNITY

Elevated Expression of Paneth Cell CRS4C in Ileitis-prone SAMP1/YitFc Mice

(2010) Michael T. Shanahan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Induction and rescue of Nod2-dependent Th1-driven granulomatous inflammation of the ileum

(2010) A. Biswas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Salmonella enterica Serovar Typhimurium Pathogenicity Island 1-Encoded Type III Secretion System Translocases Mediate Intimate Attachment to Nonphagocytic Cells

(2009) M. Lara-Tejero et al.   INFECTION AND IMMUNITY

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

Enteric defensins are essential regulators of intestinal microbial ecology

(2009) Nita H Salzman et al.   NATURE IMMUNOLOGY

Nod2 is required for the regulation of commensal microbiota in the intestine

(2009) T. Petnicki-Ocwieja et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reduced  -defensin expression is associated with inflammation and not NOD2 mutation status in ileal Crohn's disease

(2008) L A Simms et al.   GUT