Identification of shared and unique susceptibility pathways among cancers of the lung, breast, and prostate from genome-wide association studies and tissue-specific protein interactions
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Title
Identification of shared and unique susceptibility pathways among cancers of the lung, breast, and prostate from genome-wide association studies and tissue-specific protein interactions
Authors
Keywords
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Journal
HUMAN MOLECULAR GENETICS
Volume 24, Issue 25, Pages 7406-7420
Publisher
Oxford University Press (OUP)
Online
2015-10-28
DOI
10.1093/hmg/ddv440
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Note: Only part of the references are listed.- Gene set analysis: A step-by-step guide
- (2015) Michael A. Mooney et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
- New genetic loci link adipose and insulin biology to body fat distribution
- (2015) Dmitry Shungin et al. NATURE
- Understanding multicellular function and disease with human tissue-specific networks
- (2015) Casey S Greene et al. NATURE GENETICS
- FTO Obesity Variant Circuitry and Adipocyte Browning in Humans
- (2015) Melina Claussnitzer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Prostate-specific G-protein-coupled receptor collaborates with loss of PTEN to promote prostate cancer progression
- (2015) M Rodriguez et al. ONCOGENE
- High burden and pervasive positive selection of somatic mutations in normal human skin
- (2015) I. Martincorena et al. SCIENCE
- The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans
- (2015) et al. SCIENCE
- Integrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis
- (2014) Supinda Bunyavanich et al. BMC Medical Genomics
- Protein interaction networks as metric spaces: a novel perspective on distribution of hubs
- (2014) Emad Fadhal et al. BMC Systems Biology
- Pathway analysis of genome-wide association study on serum prostate-specific antigen levels
- (2014) Yu-Zheng Ge et al. GENE
- Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer
- (2014) Yufei Wang et al. NATURE GENETICS
- Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics
- (2014) Alicia Lundby et al. NATURE METHODS
- The BioGRID interaction database: 2015 update
- (2014) Andrew Chatr-aryamontri et al. NUCLEIC ACIDS RESEARCH
- fcGENE: A Versatile Tool for Processing and Transforming SNP Datasets
- (2014) Nab Raj Roshyara et al. PLoS One
- Functional and genomic context in pathway analysis of GWAS data
- (2014) Michael A. Mooney et al. TRENDS IN GENETICS
- Genome-wide pathway analysis of breast cancer
- (2014) Young Ho Lee et al. TUMOR BIOLOGY
- Integrating sequence and array data to create an improved 1000 Genomes Project haplotype reference panel
- (2014) Olivier Delaneau et al. Nature Communications
- Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease
- (2014) Ville-Petteri Mäkinen et al. PLoS Genetics
- Beyond GWASs: Illuminating the Dark Road from Association to Function
- (2013) Stacey L. Edwards et al. AMERICAN JOURNAL OF HUMAN GENETICS
- A novel and essential role for Fc RIIa in cancer cell-induced platelet activation
- (2013) A. Mitrugno et al. BLOOD
- Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease
- (2013) Bin Zhang et al. CELL
- Molecular Pathways: Adiponectin and Leptin Signaling in Cancer
- (2013) M. N. VanSaun CLINICAL CANCER RESEARCH
- Network-assisted analysis to prioritize GWAS results: principles, methods and perspectives
- (2013) Peilin Jia et al. HUMAN GENETICS
- Obesity induced a leptin-Notch signaling axis in breast cancer
- (2013) Monica Battle et al. INTERNATIONAL JOURNAL OF CANCER
- Cytokine patterns in patients with cancer: a systematic review
- (2013) Bodo E Lippitz LANCET ONCOLOGY
- The Genotype-Tissue Expression (GTEx) project
- (2013) John Lonsdale et al. NATURE GENETICS
- Innate and adaptive immune cells in the tumor microenvironment
- (2013) Thomas F Gajewski et al. NATURE IMMUNOLOGY
- Genetic insights into common pathways and complex relationships among immune-mediated diseases
- (2013) Miles Parkes et al. NATURE REVIEWS GENETICS
- Expression Atlas update—a database of gene and transcript expression from microarray- and sequencing-based functional genomics experiments
- (2013) Robert Petryszak et al. NUCLEIC ACIDS RESEARCH
- The Reactome pathway knowledgebase
- (2013) David Croft et al. NUCLEIC ACIDS RESEARCH
- Molecular targets for cancer therapy in the PI3K/AKT/mTOR pathway
- (2013) Jiri Polivka et al. PHARMACOLOGY & THERAPEUTICS
- Pathway-Based Analysis Using Genome-wide Association Data from a Korean Non-Small Cell Lung Cancer Study
- (2013) Donghoon Lee et al. PLoS One
- Tissue specificity in the nuclear envelope supports its functional complexity
- (2013) Jose I de las Heras et al. Nucleus
- Alzheimer Disease Susceptibility Loci: Evidence for a Protein Network under Natural Selection
- (2012) Towfique Raj et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Integrating GWAS and Expression Data for Functional Characterization of Disease-Associated SNPs: An Application to Follicular Lymphoma
- (2012) Lucia Conde et al. AMERICAN JOURNAL OF HUMAN GENETICS
- The μ-Opioid Receptor in Cancer Progression
- (2012) Frances E. Lennon et al. ANESTHESIOLOGY
- Common Genetic Variants and Gene-Expression Changes Associated with Bipolar Disorder Are Over-Represented in Brain Signaling Pathway Genes
- (2012) Inti Pedroso et al. BIOLOGICAL PSYCHIATRY
- Integrative pathway analysis of genome-wide association studies and gene expression data in prostate cancer
- (2012) Peilin Jia et al. BMC Systems Biology
- Stromal cells in tumor microenvironment and breast cancer
- (2012) Yan Mao et al. CANCER AND METASTASIS REVIEWS
- Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis
- (2012) L. Ouyang et al. CELL PROLIFERATION
- A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease
- (2012) A. Amin Al Olama et al. HUMAN MOLECULAR GENETICS
- A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11
- (2012) Afshan Siddiq et al. HUMAN MOLECULAR GENETICS
- Leptin-induced Epithelial-Mesenchymal Transition in Breast Cancer Cells Requires β-Catenin Activation via Akt/GSK3- and MTA1/Wnt1 Protein-dependent Pathways
- (2012) Dan Yan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Aspirin Use and the Risk of Prostate Cancer Mortality in Men Treated With Prostatectomy or Radiotherapy
- (2012) Kevin S. Choe et al. JOURNAL OF CLINICAL ONCOLOGY
- Genetic insights in Alzheimer's disease
- (2012) Karolien Bettens et al. LANCET NEUROLOGY
- Molecular pathology of lung cancer: key to personalized medicine
- (2012) Liang Cheng et al. MODERN PATHOLOGY
- Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits
- (2012) Jian Yang et al. NATURE GENETICS
- The TissueNet database of human tissue protein–protein interactions
- (2012) Ruth Barshir et al. NUCLEIC ACIDS RESEARCH
- Comparison of Pathway Analysis Approaches Using Lung Cancer GWAS Data Sets
- (2012) Gordon Fehringer et al. PLoS One
- Pathway analysis of genomic data: concepts, methods, and prospects for future development
- (2012) Vijay K. Ramanan et al. TRENDS IN GENETICS
- Network-Assisted Investigation of Combined Causal Signals from Genome-Wide Association Studies in Schizophrenia
- (2012) Peilin Jia et al. PLoS Computational Biology
- Common Breast Cancer Susceptibility Loci Are Associated with Triple-Negative Breast Cancer
- (2011) K. N. Stevens et al. CANCER RESEARCH
- Molecular biology in breast cancer: Intrinsic subtypes and signaling pathways
- (2011) Pilar Eroles et al. CANCER TREATMENT REVIEWS
- Replication and cumulative effects of GWAS-identified genetic variations for prostate cancer in Asians: a case–control study in the ChinaPCa consortium
- (2011) Meilin Wang et al. CARCINOGENESIS
- Genome-wide association study identifies new prostate cancer susceptibility loci
- (2011) Fredrick R. Schumacher et al. HUMAN MOLECULAR GENETICS
- Pathway-driven gene stability selection of two rheumatoid arthritis GWAS identifies and validates new susceptibility genes in receptor mediated signalling pathways
- (2011) Hariklia Eleftherohorinou et al. HUMAN MOLECULAR GENETICS
- New driver mutations in non-small-cell lung cancer
- (2011) William Pao et al. LANCET ONCOLOGY
- A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor–negative breast cancer
- (2011) Christopher A Haiman et al. NATURE GENETICS
- A linear complexity phasing method for thousands of genomes
- (2011) Olivier Delaneau et al. NATURE METHODS
- MINT, the molecular interaction database: 2012 update
- (2011) Luana Licata et al. NUCLEIC ACIDS RESEARCH
- The IntAct molecular interaction database in 2012
- (2011) S. Kerrien et al. NUCLEIC ACIDS RESEARCH
- A refined molecular taxonomy of breast cancer
- (2011) M Guedj et al. ONCOGENE
- A Systems Approach to the Biology of Mood Disorders through Network Analysis of Candidate Genes
- (2011) S. D. Detera-Wadleigh et al. PHARMACOPSYCHIATRY
- Shared Molecular and Functional Frameworks among Five Complex Human Disorders: A Comparative Study on Interactomes Linked to Susceptibility Genes
- (2011) Ramesh Menon et al. PLoS One
- Unbalanced oxidant-induced DNA damage and repair in COPD: a link towards lung cancer
- (2011) G. Caramori et al. THORAX
- Pervasive Sharing of Genetic Effects in Autoimmune Disease
- (2011) Chris Cotsapas et al. PLoS Genetics
- Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology
- (2011) Elizabeth J. Rossin et al. PLoS Genetics
- Nerve Growth Factor in Cancer Cell Death and Survival
- (2011) Niamh Molloy et al. Cancers
- Integrating Pathway Analysis and Genetics of Gene Expression for Genome-wide Association Studies
- (2010) Hua Zhong et al. AMERICAN JOURNAL OF HUMAN GENETICS
- GCTA: A Tool for Genome-wide Complex Trait Analysis
- (2010) Jian Yang et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Tissue kallikrein promotes prostate cancer cell migration and invasion via a protease-activated receptor-1-dependent signaling pathway
- (2010) Lin Gao et al. BIOLOGICAL CHEMISTRY
- Genetic variation influences glutamate concentrations in brains of patients with multiple sclerosis
- (2010) Sergio E. Baranzini et al. BRAIN
- A combined analysis of genome-wide association studies in breast cancer
- (2010) Jingmei Li et al. BREAST CANCER RESEARCH AND TREATMENT
- Pathway Analysis of Breast Cancer Genome-Wide Association Study Highlights Three Pathways and One Canonical Signaling Cascade
- (2010) Idan Menashe et al. CANCER RESEARCH
- Genome-Wide Association Studies of Cancer
- (2010) Zsofia K. Stadler et al. JOURNAL OF CLINICAL ONCOLOGY
- A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general population
- (2010) Antonis C Antoniou et al. NATURE GENETICS
- Genome-wide association study identifies five new breast cancer susceptibility loci
- (2010) Clare Turnbull et al. NATURE GENETICS
- Analysing biological pathways in genome-wide association studies
- (2010) Kai Wang et al. NATURE REVIEWS GENETICS
- Network medicine: a network-based approach to human disease
- (2010) Albert-László Barabási et al. NATURE REVIEWS GENETICS
- Guidance molecules in lung cancer
- (2010) Patrick Nasarre et al. Cell Adhesion & Migration
- Gene Ontology Analysis of GWA Study Data Sets Provides Insights into the Biology of Bipolar Disorder
- (2009) Peter Holmans et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Genome-wide association studies in cancer--current and future directions
- (2009) C. C. Chung et al. CARCINOGENESIS
- Mutations of multiple genes cause deregulation of NF-κB in diffuse large B-cell lymphoma
- (2009) Mara Compagno et al. NATURE
- Identification of seven new prostate cancer susceptibility loci through a genome-wide association study
- (2009) Rosalind A Eeles et al. NATURE GENETICS
- Mortality Results from a Randomized Prostate-Cancer Screening Trial
- (2009) Gerald L. Andriole et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies
- (2009) Bryan N. Howie et al. PLoS Genetics
- BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources
- (2009) Chunlei Wu et al. GENOME BIOLOGY
- A global pathway crosstalk network
- (2008) Yong Li et al. BIOINFORMATICS
- Identification of low penetrance alleles for lung cancer: The GEnetic Lung CAncer Predisposition Study (GELCAPS)
- (2008) Tim Eisen et al. BMC CANCER
- Environment And Genetics in Lung cancer Etiology (EAGLE) study: An integrative population-based case-control study of lung cancer
- (2008) Maria Teresa Landi et al. BMC PUBLIC HEALTH
- Matrix Metalloproteinase 1 (MMP1) Is Associated with Early-Onset Lung Cancer
- (2008) W. Sauter et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Pathways-based analyses of whole-genome association study data in bipolar disorder reveal genes mediating ion channel activity and synaptic neurotransmission
- (2008) Kathleen Askland et al. HUMAN GENETICS
- Risk of different histological types of postmenopausal breast cancer by type and regimen of menopausal hormone therapy
- (2008) Dieter Flesch-Janys et al. INTERNATIONAL JOURNAL OF CANCER
- A Genecentric Human Protein Atlas for Expression Profiles Based on Antibodies
- (2008) Lisa Berglund et al. MOLECULAR & CELLULAR PROTEOMICS
- A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25
- (2008) Rayjean J. Hung et al. NATURE
- Common 5p15.33 and 6p21.33 variants influence lung cancer risk
- (2008) Yufei Wang et al. NATURE GENETICS
- NAD(P)H:quinone oxidoreductase 1 NQO1*2 genotype (P187S) is a strong prognostic and predictive factor in breast cancer
- (2008) Rainer Fagerholm et al. NATURE GENETICS
- Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1
- (2008) Christopher I Amos et al. NATURE GENETICS
- Multiple newly identified loci associated with prostate cancer susceptibility
- (2008) Rosalind A Eeles et al. NATURE GENETICS
- Stromal Gene Signatures in Large-B-Cell Lymphomas
- (2008) G. Lenz et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mapping the Genetic Architecture of Gene Expression in Human Liver
- (2008) Eric E Schadt et al. PLOS BIOLOGY
- High-Resolution Mapping of Expression-QTLs Yields Insight into Human Gene Regulation
- (2008) Jean-Baptiste Veyrieras et al. PLoS Genetics
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