Impaired retrograde transport by the Dynein/Dynactin complex contributes to Tau-induced toxicity

Microtubule-stabilizing agents as potential therapeutics for neurodegenerative disease

(2014) Kurt R. Brunden et al.   BIOORGANIC & MEDICINAL CHEMISTRY

In vivo axonal transport deficits in a mouse model of fronto-temporal dementia

(2014) Tabassum Majid et al.   NeuroImage-Clinical

Drosophilaas a screening tool to study human neurodegenerative diseases

(2013) Sarah Lenz et al.   JOURNAL OF NEUROCHEMISTRY

Drosophila melanogaster as a model organism for Alzheimer’s disease

(2013) Katja Prüßing et al.   Molecular Neurodegeneration

Biased Brownian ratcheting leads to pre-mRNA remodeling and capture prior to first-step splicing

(2013) Ramya Krishnan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Knockdown of Hsc70-5/mortalin Induces Loss of Synaptic Mitochondria in a Drosophila Parkinson’s Disease Model

(2013) Jun-yi Zhu et al.   PLoS One

The Microtubule-Stabilizing Agent, Epothilone D, Reduces Axonal Dysfunction, Neurotoxicity, Cognitive Deficits, and Alzheimer-Like Pathology in an Interventional Study with Aged Tau Transgenic Mice

(2012) B. Zhang et al.   JOURNAL OF NEUROSCIENCE

Large-Scale Screen for Modifiers of Ataxin-3-Derived Polyglutamine-Induced Toxicity in Drosophila

(2012) Hannes Voßfeldt et al.   PLoS One

Spastic Paraplegia Mutation N256S in the Neuronal Microtubule Motor KIF5A Disrupts Axonal Transport in a Drosophila HSP Model

(2012) Petra Füger et al.   PLoS Genetics

Functional genomic screen and network analysis reveal novel modifiers of tauopathy dissociated from tau phosphorylation

(2011) Surendra S. Ambegaokar et al.   HUMAN MOLECULAR GENETICS

The Power and Richness of Modelling Tauopathies in Drosophila

(2011) Katerina Papanikolopoulou et al.   MOLECULAR NEUROBIOLOGY

Soluble hyper-phosphorylated tau causes microtubule breakdown and functionally compromises normal tau in vivo

(2010) Catherine M. Cowan et al.   ACTA NEUROPATHOLOGICA

Cwc25 Is a Novel Splicing Factor Required after Prp2 and Yju2 To Facilitate the First Catalytic Reaction

(2009) Y.-F. Chiu et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulators of the cytoplasmic dynein motor

(2009) Julia R. Kardon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Differential Regulation of Dynein and Kinesin Motor Proteins by Tau

(2008) R. Dixit et al.   SCIENCE

Tau-Induced Traffic Jams Reflect Organelles Accumulation at Points of Microtubule Polar Mismatching

(2008) Or A. Shemesh et al.   TRAFFIC

Polyglutamine Genes Interact to Modulate the Severity and Progression of Neurodegeneration in Drosophila

(2008) Derek Lessing et al.   PLOS BIOLOGY