Vitamin D3 Supplementation Reduces Subsequent Brain Injury and Inflammation Associated with Ischemic Stroke

Acute or Delayed Systemic Administration of Human Amnion Epithelial Cells Improves Outcomes in Experimental Stroke

(2018) Megan A. Evans et al.   STROKE

Diet-induced vitamin D deficiency has no effect on acute post-stroke outcomes in young male mice

(2017) Megan A Evans et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Functional genomics analysis of vitamin D effects on CD4+ T cells in vivo in experimental autoimmune encephalomyelitis ‬

(2017) Manuel Zeitelhofer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vitamin D Receptor Activation Reduces Angiotensin-II–Induced Dissecting Abdominal Aortic Aneurysm in Apolipoprotein E–Knockout MiceHighlights

(2016) Sara Martorell et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Vitamin D3 alters microglia immune activation by an IL-10 dependent SOCS3 mechanism

(2016) Mandy Boontanrart et al.   JOURNAL OF NEUROIMMUNOLOGY

Vitamin D interacts with Esr1 and Igf1 to regulate molecular pathways relevant to Alzheimer’s disease

(2016) Véréna Landel et al.   Molecular Neurodegeneration

Commensal microbiota affects ischemic stroke outcome by regulating intestinal γδ T cells

(2016) Corinne Benakis et al.   NATURE MEDICINE

1,25-Dihydroxyvitamin D3 Facilitates M2 Polarization and Upregulates TLR10 Expression on Human Microglial Cells

(2016) Rewa Verma et al.   NEUROIMMUNOMODULATION

Inflammation and Stroke: An Overview

(2016) Josef Anrather et al.   Neurotherapeutics

1,25D3 prevents CD8+Tc2 skewing and asthma development through VDR binding changes to the Cyp11a1 promoter

(2016) Michaela Schedel et al.   Nature Communications

Vitamin D Receptor Activation Protects Against Myocardial Reperfusion Injury Through Inhibition of Apoptosis and Modulation of Autophagy

(2015) Tianbao Yao et al.   ANTIOXIDANTS & REDOX SIGNALING

Serum Vitamin D Status as a Predictor of Prognosis in Patients with Acute Ischemic Stroke

(2015) Kwang-Yeol Park et al.   CEREBROVASCULAR DISEASES

Heart Disease and Stroke Statistics—2016 Update

(2015) Dariush Mozaffarian et al.   CIRCULATION

Optimal Vitamin D Supplementation Levels for Cardiovascular Disease Protection

(2015) Sebastian T. Lugg et al.   DISEASE MARKERS

Low Serum Vitamin D Is Independently Associated with Larger Lesion Volumes after Ischemic Stroke

(2015) Anya Turetsky et al.   Journal of Stroke & Cerebrovascular Diseases

Safety and immunologic effects of high- vs low-dose cholecalciferol in multiple sclerosis

(2015) Elias S. Sotirchos et al.   NEUROLOGY

Evidence That Ly6ChiMonocytes Are Protective in Acute Ischemic Stroke by Promoting M2 Macrophage Polarization

(2015) Hannah X. Chu et al.   STROKE

The role of microglia and myeloid immune cells in acute cerebral ischemia

(2015) Corinne Benakis et al.   Frontiers in Cellular Neuroscience

Low Serum Vitamin D Is Independently Associated with Larger Lesion Volumes after Ischemic Stroke

(2015) Anya Turetsky et al.   Journal of Stroke & Cerebrovascular Diseases

Vitamin D Prevents Hypoxia/Reoxygenation-Induced Blood-Brain Barrier Disruption via Vitamin D Receptor-Mediated NF-kB Signaling Pathways

(2015) Soonmi Won et al.   PLoS One

Effect of a Selective Mas Receptor Agonist in Cerebral Ischemia In Vitro and In Vivo

(2015) Seyoung Lee et al.   PLoS One

Vitamin D Promotes Vascular Regeneration

(2014) Michael Sze Ka Wong et al.   CIRCULATION

Prognostic Value of Serum 25-Hydroxyvitamin D in Patients with Stroke

(2014) Yan Wang et al.   NEUROCHEMICAL RESEARCH

Vitamin D upregulates glutamate cysteine ligase and glutathione reductase, and GSH formation, and decreases ROS and MCP-1 and IL-8 secretion in high-glucose exposed U937 monocytes

(2013) Sushil K. Jain et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Serum 25-hydroxyvitamin D predicts the short-term outcomes of Chinese patients with acute ischaemic stroke

(2013) Wen-Jun Tu et al.   CLINICAL SCIENCE

One calcitriol dose transiently increases Helios+FoxP3+ T cells and ameliorates autoimmune demyelinating disease

(2013) Faye E. Nashold et al.   JOURNAL OF NEUROIMMUNOLOGY

Neuroprotective effect of calcitriol on ischemic/reperfusion injury through the NR3A/CREB pathways in the rat hippocampus

(2013) JUN FU et al.   Molecular Medicine Reports

1,25-Dihydroxyvitamin D3 selectively and reversibly impairs T helper-cell CNS localization

(2013) I. V. Grishkan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke

(2012) M. Gelderblom et al.   BLOOD

Calcitriol protects renovascular function in hypertension by down-regulating angiotensin II type 1 receptors and reducing oxidative stress

(2012) Jinghui Dong et al.   EUROPEAN HEART JOURNAL

Serum 25-hydroxyvitamin D predicts severity and prognosis in stroke patients

(2012) B. Daubail et al.   EUROPEAN JOURNAL OF NEUROLOGY

1,25-Dihydroxyvitamin D3 curtails the inflammatory and T cell stimulatory capacity of macrophages through an IL-10-dependent mechanism

(2012) Hannelie Korf et al.   IMMUNOBIOLOGY

The Ifng Gene Is Essential for Vdr Gene Expression and Vitamin D3-Mediated Reduction of the Pathogenic T Cell Burden in the Central Nervous System in Experimental Autoimmune Encephalomyelitis, a Multiple Sclerosis Model

(2012) J. A. Spanier et al.   JOURNAL OF IMMUNOLOGY

Vitamin D Inhibits Monocyte/Macrophage Proinflammatory Cytokine Production by Targeting MAPK Phosphatase-1

(2012) Y. Zhang et al.   JOURNAL OF IMMUNOLOGY

24-Hydroxylase in cancer: Impact on vitamin D-based anticancer therapeutics

(2012) Wei Luo et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Distinctive Effects of T Cell Subsets in Neuronal Injury Induced by Cocultured Splenocytes In Vitro and by In Vivo Stroke in Mice

(2012) Lijuan Gu et al.   STROKE

Microglia/Macrophage Polarization Dynamics Reveal Novel Mechanism of Injury Expansion After Focal Cerebral Ischemia

(2012) Xiaoming Hu et al.   STROKE

Predominance of Th2 polarization by Vitamin D through a STAT6-dependent mechanism

(2011) Scott Sloka et al.   Journal of Neuroinflammation

1,25-Dihydroxyvitamin D3 Ameliorates Th17 Autoimmunity via Transcriptional Modulation of Interleukin-17A

(2011) S. Joshi et al.   MOLECULAR AND CELLULAR BIOLOGY

Inflammatory Gene Expression in OVE26 Diabetic Kidney during the Development of Nephropathy

(2011) Lu Yang et al.   NEPHRON EXPERIMENTAL NEPHROLOGY

Nox2 Oxidase Activity Accounts for the Oxidative Stress and Vasomotor Dysfunction in Mouse Cerebral Arteries following Ischemic Stroke

(2011) T. Michael De Silva et al.   PLoS One

Oral Administration of an Active Form of Vitamin D 3 (Calcitriol) Decreases Atherosclerosis in Mice by Inducing Regulatory T Cells and Immature Dendritic Cells With Tolerogenic Functions

(2010) Masafumi Takeda et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Topical 1,25-dihydroxyvitamin D3 subverts the priming ability of draining lymph node dendritic cells

(2010) Shelley Gorman et al.   IMMUNOLOGY

Vitamin D Suppresses Th17 Cytokine Production by Inducing C/EBP Homologous Protein (CHOP) Expression

(2010) Seon Hee Chang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vitamin D controls T cell antigen receptor signaling and activation of human T cells

(2010) Marina Rode von Essen et al.   NATURE IMMUNOLOGY

1,25-Dihydroxyvitamin D3 Inhibits the Differentiation and Migration of TH17 Cells to Protect against Experimental Autoimmune Encephalomyelitis

(2010) Jae-Hoon Chang et al.   PLoS One

Regulatory T cells: how do they suppress immune responses?

(2009) S. Sakaguchi et al.   INTERNATIONAL IMMUNOLOGY

Pivotal role of cerebral interleukin-17–producing γδT cells in the delayed phase of ischemic brain injury

(2009) Takashi Shichita et al.   NATURE MEDICINE

Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke

(2009) Arthur Liesz et al.   NATURE MEDICINE

Temporal and Spatial Dynamics of Cerebral Immune Cell Accumulation in Stroke

(2009) Mathias Gelderblom et al.   STROKE

Expansion of the Time Window for Treatment of Acute Ischemic Stroke With Intravenous Tissue Plasminogen Activator

(2009) Gregory J. del Zoppo et al.   STROKE

Vitamin D Deficiency

(2008) John H. Lee et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

National US Estimates of Recombinant Tissue Plasminogen Activator Use

(2008) Dawn Kleindorfer et al.   STROKE