Functional genomics analysis of vitamin D effects on CD4+ T cells in vivo in experimental autoimmune encephalomyelitis ‬

The multiple sclerosis susceptibility genes TAGAP and IL2RA are regulated by vitamin D in CD4+ T cells

(2016) T Berge et al.   GENES AND IMMUNITY

Vitamin D Status During Pregnancy and Risk of Multiple Sclerosis in Offspring of Women in the Finnish Maternity Cohort

(2016) Kassandra L. Munger et al.   JAMA Neurology

Vitamin D and estrogen synergy in Vdr-expressing CD4+ T cells is essential to induce Helios+FoxP3+ T cells and prevent autoimmune demyelinating disease

(2015) Justin A. Spanier et al.   JOURNAL OF NEUROIMMUNOLOGY

Effect of high dose vitamin D intake on interleukin-17 levels in multiple sclerosis: A randomized, double-blind, placebo-controlled clinical trial

(2015) Nafiseh Toghianifar et al.   JOURNAL OF NEUROIMMUNOLOGY

STAT4 controls GM-CSF production by both Th1 and Th17 cells during EAE

(2015) Ian L. McWilliams et al.   Journal of Neuroinflammation

Function and information content of DNA methylation

(2015) Dirk Schübeler   NATURE

Development of a unique epigenetic signature during in vivo Th17 differentiation

(2015) Bi-Huei Yang et al.   NUCLEIC ACIDS RESEARCH

Epigenome-wide effects of vitamin D and their impact on the transcriptome of human monocytes involve CTCF

(2015) Sabine Seuter et al.   NUCLEIC ACIDS RESEARCH

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Functional inflammatory profiles distinguish myelin-reactive T cells from patients with multiple sclerosis

(2015) Yonghao Cao et al.   Science Translational Medicine

MiR-125a targets effector programs to stabilize Treg-mediated immune homeostasis

(2015) Wen Pan et al.   Nature Communications

Acute treatment with valproic acid and l-thyroxine ameliorates clinical signs of experimental autoimmune encephalomyelitis and prevents brain pathology in DA rats

(2014) Gonçalo Castelo-Branco et al.   NEUROBIOLOGY OF DISEASE

Patterns of Genome-Wide VDR Locations

(2014) Pauli Tuoresmäki et al.   PLoS One

Vitamin D and the epigenome

(2014) Irfete S. Fetahu et al.   Frontiers in Physiology

Vitamin D and the RNA transcriptome: more than mRNA regulation

(2014) Moray J. Campbell   Frontiers in Physiology

Metabolic Regulation of T Lymphocytes

(2013) Nancie J. MacIver et al.   Annual Review of Immunology

Vitamin D receptor ChIP-seq in primary CD4+ cells: relationship to serum 25-hydroxyvitamin D levels and autoimmune disease

(2013) Adam E Handel et al.   BMC Medicine

Efficacy of vitamin D in treating multiple sclerosis-like neuroinflammation depends on developmental stage

(2013) Milena Z. Adzemovic et al.   EXPERIMENTAL NEUROLOGY

MicroRNA-627 Mediates the Epigenetic Mechanisms of Vitamin D to Suppress Proliferation of Human Colorectal Cancer Cells and Growth of Xenograft Tumors in Mice

(2013) Sathish K.R. Padi et al.   GASTROENTEROLOGY

Coordinated Changes in DNA Methylation in Antigen-Specific Memory CD4 T Cells

(2013) S.-i. Hashimoto et al.   JOURNAL OF IMMUNOLOGY

If I had a clinically isolated syndrome with MRI diagnostic of MS, I would take vitamin D 10,000 IU daily: No

(2013) C. Papeix et al.   Multiple Sclerosis Journal

Vitamin D status predicts new brain magnetic resonance imaging activity in multiple sclerosis

(2012) Ellen M. Mowry et al.   ANNALS OF NEUROLOGY

Epigenetic mechanisms in anti-cancer actions of bioactive food components - the implications in cancer prevention

(2012) B Stefanska et al.   BRITISH JOURNAL OF PHARMACOLOGY

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Vitamin D in Systemic and Organ-Specific Autoimmune Diseases

(2012) Nancy Agmon-Levin et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

MicroRNA-22 is induced by vitamin D and contributes to its antiproliferative, antimigratory and gene regulatory effects in colon cancer cells

(2012) Silvia Alvarez-Díaz et al.   HUMAN MOLECULAR GENETICS

The Antiepileptic Drug Valproic Acid Restores T Cell Homeostasis and Ameliorates Pathogenesis of Experimental Autoimmune Encephalomyelitis

(2012) Jie Lv et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Genome-Wide Methylation Study of Severe Vitamin D Deficiency in African American Adolescents

(2012) Haidong Zhu et al.   JOURNAL OF PEDIATRICS

Metabolic checkpoints in activated T cells

(2012) Ruoning Wang et al.   NATURE IMMUNOLOGY

Vitamin D as a protective factor in multiple sclerosis

(2012) J. Salzer et al.   NEUROLOGY

Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation

(2012) Davis J. McCarthy et al.   NUCLEIC ACIDS RESEARCH

Detecting Differential Expression in RNA-sequence Data Using Quasi-likelihood with Shrunken Dispersion Estimates

(2012) Steven P. Lund et al.   Statistical Applications in Genetics and Molecular Biology

Emerging patterns of genetic overlap across autoimmune disorders

(2012) Corinne Richard-Miceli et al.   Genome Medicine

Rare variants in the CYP27B1 gene are associated with multiple sclerosis

(2011) Sreeram V. Ramagopalan et al.   ANNALS OF NEUROLOGY

1,25-Dihydroxyvitamin D3 acts directly on the T lymphocyte vitamin D receptor to inhibit experimental autoimmune encephalomyelitis

(2011) Christopher G. Mayne et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Early Th1 Cell Differentiation Is Marked by a Tfh Cell-like Transition

(2011) Shingo Nakayamada et al.   IMMUNITY

HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Tregcells

(2011) Lewis Z. Shi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

1,25-Dihydroxyvitamin D3 Ameliorates Th17 Autoimmunity via Transcriptional Modulation of Interleukin-17A

(2011) S. Joshi et al.   MOLECULAR AND CELLULAR BIOLOGY

VDR/RXR and TCF4/β-Catenin Cistromes in Colonic Cells of Colorectal Tumor Origin: Impact onc-FOSandc-MYCGene Expression

(2011) Mark B. Meyer et al.   MOLECULAR ENDOCRINOLOGY

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation

(2011) Laura Codarri et al.   NATURE IMMUNOLOGY

Nuclear hormone 1α,25-dihydroxyvitamin D3 elicits a genome-wide shift in the locations of VDR chromatin occupancy

(2011) Sami Heikkinen et al.   NUCLEIC ACIDS RESEARCH

T cell receptor recognition of self and foreign antigens in the induction of autoimmunity

(2011) Kai W. Wucherpfennig et al.   SEMINARS IN IMMUNOLOGY

Accurate genome-scale percentage DNA methylation estimates from microarray data

(2010) M. J. Aryee et al.   BIOSTATISTICS

Vitamin D stimulates apoptosis in gastric cancer cells in synergy with trichostatin A /sodium butyrate-induced and 5-aza-2′-deoxycytidine-induced PTEN upregulation

(2010) Lina Pan et al.   FEBS Journal

A ChIP-seq defined genome-wide map of vitamin D receptor binding: Associations with disease and evolution

(2010) S. V. Ramagopalan et al.   GENOME RESEARCH

The Vitamin D Analog, TX527, Promotes a Human CD4+CD25highCD127low Regulatory T Cell Profile and Induces a Migratory Signature Specific for Homing to Sites of Inflammation

(2010) F. Baeke et al.   JOURNAL OF IMMUNOLOGY

Dietary intake of vitamin D during adolescence and risk of multiple sclerosis

(2010) Kassandra L. Munger et al.   JOURNAL OF NEUROLOGY

Vitamin D and multiple sclerosis

(2010) Alberto Ascherio et al.   LANCET NEUROLOGY

Vitamin D, disease and therapeutic opportunities

(2010) Lori A. Plum et al.   NATURE REVIEWS DRUG DISCOVERY

1,25-Dihydroxyvitamin D3 Inhibits the Differentiation and Migration of TH17 Cells to Protect against Experimental Autoimmune Encephalomyelitis

(2010) Jae-Hoon Chang et al.   PLoS One

Does Vitamin D Affect Risk of Developing Autoimmune Disease?: A Systematic Review

(2010) Martin A. Kriegel et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Characterization of Multiple Sclerosis candidate gene expression kinetics in rat experimental autoimmune encephalomyelitis

(2009) Melanie Thessen Hedreul et al.   JOURNAL OF NEUROIMMUNOLOGY

Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20

(2009) Melanie Bahlo et al.   NATURE GENETICS

MBD-isolated Genome Sequencing provides a high-throughput and comprehensive survey of DNA methylation in the human genome

(2009) David Serre et al.   NUCLEIC ACIDS RESEARCH

Comprehensive high-throughput arrays for relative methylation (CHARM)

(2008) R. A. Irizarry et al.   GENOME RESEARCH