A designer enzyme for hydrazone and oxime formation featuring an unnatural catalytic aniline residue

Multidrug resistance regulators (MDRs) as scaffolds for the design of artificial metalloenzymes

(2017) Manuela Bersellini et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

The use of unnatural amino acids to study and engineer protein function

(2016) Petra Neumann-Staubitz et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

A Chemically Programmed Proximal Ligand Enhances the Catalytic Properties of a Heme Enzyme

(2016) Anthony P. Green et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The coming of age of de novo protein design

(2016) Po-Ssu Huang et al.   NATURE

Expanding the Enzyme Universe: Accessing Non-Natural Reactions by Mechanism-Guided Directed Evolution

(2015) Hans Renata et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

De novo protein design: how do we expand into the universe of possible protein structures?

(2015) Derek N Woolfson et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Supramolecular Assembly of Artificial Metalloenzymes Based on the Dimeric Protein LmrR as Promiscuous Scaffold

(2015) Jeffrey Bos et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Designing logical codon reassignment – Expanding the chemistry in biology

(2015) Anaëlle Dumas et al.   Chemical Science

Novel artificial metalloenzymes by in vivo incorporation of metal-binding unnatural amino acids

(2015) Ivana Drienovská et al.   Chemical Science

Formylglycine, a Post-Translationally Generated Residue with Unique Catalytic Capabilities and Biotechnology Applications

(2014) Mason J. Appel et al.   ACS Chemical Biology

Metalloprotein design using genetic code expansion

(2014) Cheng Hu et al.   CHEMICAL SOCIETY REVIEWS

Computational Enzyme Design

(2013) Gert Kiss et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design of Protein Catalysts

(2013) Donald Hilvert   Annual Review of Biochemistry

Enhanced Catalysis of Oxime-Based Bioconjugations by Substituted Anilines

(2013) Michaela Wendeler et al.   BIOCONJUGATE CHEMISTRY

Water-Soluble Organocatalysts for Hydrazone and Oxime Formation

(2013) Pete Crisalli et al.   JOURNAL OF ORGANIC CHEMISTRY

Importance of ortho Proton Donors in Catalysis of Hydrazone Formation

(2013) Pete Crisalli et al.   ORGANIC LETTERS

Enantioselective Artificial Metalloenzymes by Creation of a Novel Active Site at the Protein Dimer Interface

(2012) Jeffrey Bos et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Detection of Cellular Sialic Acid Content Using Nitrobenzoxadiazole Carbonyl-Reactive Chromophores

(2012) Jessie A. Key et al.   BIOCONJUGATE CHEMISTRY

Crystal Structures of Two Transcriptional Regulators from Bacillus cereus Define the Conserved Structural Features of a PadR Subfamily

(2012) Guntur Fibriansah et al.   PLoS One

Adding New Chemistries to the Genetic Code

(2010) Chang C. Liu et al.   Annual Review of Biochemistry

Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction

(2010) J. B. Siegel et al.   SCIENCE

Structure and chemistry of 4-methylideneimidazole-5-one containing enzymes

(2009) Heather A Cooke et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Designing artificial enzymes by intuition and computation

(2009) Vikas Nanda et al.   Nature Chemistry

Oxidative coupling of peptides to a virus capsid containing unnatural amino acids

(2008) Zachary M. Carrico et al.   CHEMICAL COMMUNICATIONS

Structure of the transcriptional regulator LmrR and its mechanism of multidrug recognition

(2008) Pramod Kumar Madoori et al.   EMBO JOURNAL