Selenides and Diselenides: A Review of Their Anticancer and Chemopreventive Activity

Natural selenium particles from Staphylococcus carnosus : Hazards or particles with particular promise?

(2017) Ethiene Castellucci Estevam et al.   JOURNAL OF HAZARDOUS MATERIALS

Design, Synthesis, and Biological Evaluation of Novel Selenium-Containing Isocombretastatins and Phenstatins as Antitumor Agents

(2017) Yanqing Pang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Topological and quantum molecular descriptors as effective tools for analyzing cytotoxic activity achieved by a series of (diselanediyldibenzene-4,1-diylnide)biscarbamate derivatives

(2017) María Font et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

Antidepressant-like effect of a new selenium-containing compound is accompanied by a reduction of neuroinflammation and oxidative stress in lipopolysaccharide-challenged mice

(2017) Angela M Casaril et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Selenopheno quinolinones and coumarins promote cancer cell apoptosis by ROS depletion and caspase-7 activation

(2017) Ilona Domracheva et al.   LIFE SCIENCES

Novel Methylselenoesters as Antiproliferative Agents

(2017) Nuria Díaz-Argelich et al.   MOLECULES

Synthesis of Selenium-Quinone Hybrid Compounds with Potential Antitumor Activity via Rh-Catalyzed C-H Bond Activation and Click Reactions

(2017) Guilherme Jardim et al.   MOLECULES

Synthesis and evaluation of selenium-containing indole chalcone and diarylketone derivatives as tubulin polymerization inhibition agents

(2017) Shun Zhang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

New selenosteroids as antiproliferative agents

(2017) Alma Fuentes-Aguilar et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Application of Sodium Selenite in the Prevention and Treatment of Cancers

(2017) Marek Kieliszek et al.   Cells

Why Nature Chose Selenium

(2016) Hans J. Reich et al.   ACS Chemical Biology

Selenoproteins: Antioxidant selenoenzymes and beyond

(2016) Holger Steinbrenner et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Identification of selenocompounds with promising properties to reverse cancer multidrug resistance

(2016) Enrique Domínguez-Álvarez et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Novel seleno- and thio-urea derivatives with potent in vitro activities against several cancer cell lines

(2016) Verónica Alcolea et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, Synthesis, and Biological Evaluation of Novel Selenium (Se-NSAID) Molecules as Anticancer Agents

(2016) Daniel Plano et al.   JOURNAL OF MEDICINAL CHEMISTRY

Enhanced Glutathione Peroxidase Activity of Water-Soluble and Polyethylene Glycol-Supported Selenides, Related Spirodioxyselenuranes, and Pincer Selenuranes

(2016) Nicole M. R. McNeil et al.   JOURNAL OF ORGANIC CHEMISTRY

Selenium potentiates the anticancer effect of cisplatin against oxidative stress and calcium ion signaling-induced intracellular toxicity in MCF-7 breast cancer cells: involvement of the TRPV1 channel

(2016) Esin Sakallı Çetin et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Selenium compounds as therapeutic agents in cancer

(2015) Aristi P. Fernandes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Selenium Induces an Anti-tumor Effect Via Inhibiting Intratumoral Angiogenesis in a Mouse Model of Transplanted Canine Mammary Tumor Cells

(2015) Wenyu Li et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

In vitro radical scavenging and cytotoxic activities of novel hybrid selenocarbamates

(2015) Beatriz Romano et al.   BIOORGANIC & MEDICINAL CHEMISTRY

New Organochalcogen Multitarget Drug: Synthesis and Antioxidant and Antitumoral Activities of Chalcogenozidovudine Derivatives

(2015) Diego de Souza et al.   JOURNAL OF MEDICINAL CHEMISTRY

Selenoproteins and cardiovascular stress

(2015) Aaron H. Rose et al.   THROMBOSIS AND HAEMOSTASIS

Redox-Active Selenium Compounds—From Toxicity and Cell Death to Cancer Treatment

(2015) Sougat Misra et al.   Nutrients

Synthesis of new diorganodiselenides from organic halides: their antiproliferative effects against human breast cancer MCF-7 cells

(2014) Chaewon Kim et al.   ARCHIVES OF PHARMACAL RESEARCH

An investigation of in vitro cytotoxicity and apoptotic potential of aromatic diselenides

(2014) Masood Ahmad Rizvi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Intracellular Diagnostics: Hunting for the Mode of Action of Redox-Modulating Selenium Compounds in Selected Model Systems

(2014) Dominika Mániková et al.   MOLECULES

Diphenyl diselenide modulates oxLDL-induced cytotoxicity in macrophage by improving the redox signaling

(2013) Marcos Raniel Straliotto et al.   BIOCHIMIE

Organoselenium Compounds Modulate Extracellular Redox by Induction of Extracellular Cysteine and Cell Surface Thioredoxin Reductase

(2013) Guodong Zhang et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Which form is that? The importance of selenium speciation and metabolism in the prevention and treatment of disease

(2013) Claire M. Weekley et al.   CHEMICAL SOCIETY REVIEWS

Synthesis and antiproliferative activity of novel selenoester derivatives

(2013) Enrique Domínguez-Álvarez et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Organochalcogen peroxidase mimetics as potential drugs: a long story of a promise still unfulfilled

(2013) Laura Orian et al.   FREE RADICAL BIOLOGY AND MEDICINE

Selenium biochemistry and its role for human health

(2013) Marco Roman et al.   Metallomics

Diphenyl diselenide protects cultured MCF-7 cells against tamoxifen-induced oxidative DNA damage

(2012) M.T. Melo et al.   BIOMEDICINE & PHARMACOTHERAPY

Selenium-containing histone deacetylase inhibitors for melanoma management

(2012) Raghavendra Gowda et al.   CANCER BIOLOGY & THERAPY

Selenium and Clinical Trials: New Therapeutic Evidence for Multiple Diseases

(2012) C. Sanmartin et al.   CURRENT MEDICINAL CHEMISTRY

Induction of lung glutathione and glutamylcysteine ligase by 1,4-phenylenebis(methylene)selenocyanate and its glutathione conjugate: Role of nuclear factor-erythroid 2-related factor 2

(2012) Sans W. Emmert et al.   FREE RADICAL BIOLOGY AND MEDICINE

Selenium Compounds, Apoptosis and Other Types of Cell Death: An Overview for Cancer Therapy

(2012) Carmen Sanmartín et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Selenium and human health

(2012) Margaret P Rayman   LANCET

Substituted diaryl diselenides: Cytotoxic and apoptotic effect in human colon adenocarcinoma cells

(2012) Fernanda Nedel et al.   LIFE SCIENCES

Synthesis and antioxidant capacity of 5-selenopyranose derivatives

(2011) Corin Storkey et al.   CHEMICAL COMMUNICATIONS

Kinase Regulation by Sulfur and Selenium Containing Compounds

(2011) C. Sanmartin et al.   CURRENT CANCER DRUG TARGETS

GPx-Like Activity of Selenides and Selenoxides: Experimental Evidence for the Involvement of Hydroxy Perhydroxy Selenane as the Active Species

(2011) Vanessa Nascimento et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic application of selenium and tellurium compounds as glutathione peroxidase enzyme mimetics

(2011) Eduardo E Alberto et al.   JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY

Novel Library of Selenocompounds as Kinase Modulators

(2011) Daniel Plano et al.   MOLECULES

Enhanced Glutathione Peroxidase Activity of Conformationally Restricted Naphthaleneperi-Dichalcogenides

(2011) David J. Press et al.   ORGANIC LETTERS

Selenium in Human Health and Disease

(2010) Susan J. Fairweather-Tait et al.   ANTIOXIDANTS & REDOX SIGNALING

Selenium: a double-edged sword for defense and offence in cancer

(2010) Jela Brozmanová et al.   ARCHIVES OF TOXICOLOGY

Protective effect of binaphthyl diselenide, a synthetic organoselenium compound, on 2-nitropropane-induced hepatotoxicity in rats

(2010) Mohammad Ibrahim et al.   CELL BIOCHEMISTRY AND FUNCTION

Selenium- and Tellurium-Containing Multifunctional Redox Agents as Biochemical Redox Modulators with Selective Cytotoxicity

(2010) Vincent Jamier et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis and Selective Anticancer Activity of Organochalcogen Based Redox Catalysts

(2010) Mandy Doering et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antioxidant-Prooxidant Properties of a New Organoselenium Compound Library

(2010) Daniel Plano et al.   MOLECULES

Synthesis and Structure-Activity Correlation Studies of Secondary- and Tertiary-Amine-Based Glutathione Peroxidase Mimics

(2009) Krishna P. Bhabak et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Water-Soluble Cyclic Selenide with Enhanced Glutathione Peroxidase-Like Catalytic Activities

(2009) Fumio Kumakura et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

In vivo radioprotection studies of 3,3′-diselenodipropionic acid, a selenocystine derivative

(2009) Amit Kunwar et al.   FREE RADICAL BIOLOGY AND MEDICINE

Diphenyl diselenide protects against glycerol-induced renal damage in rats

(2009) Ricardo Brandão et al.   JOURNAL OF APPLIED TOXICOLOGY

Synthesis and Pharmacological Screening of Several Aroyl and Heteroaroyl Selenylacetic Acid Derivatives as Cytotoxic and Antiproliferative Agents

(2009) Carmen Sanmartín et al.   MOLECULES

Investigations on the role of base excision repair and non-homologous end-joining pathways in sodium selenite-induced toxicity and mutagenicity in Saccharomyces cerevisiae

(2009) Dominika Mániková et al.   MUTAGENESIS

3′3-Ditrifluoromethyldiphenyl diselenide: A new organoselenium compound with interesting antigenotoxic and antimutagenic activities

(2009) Miriana da Silva Machado et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Exploring synthetic avenues for the effective synthesis of selenium- and tellurium-containing multifunctional redox agents

(2009) Susanne Mecklenburg et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Extracellular thiol-assisted selenium uptake dependent on the xc- cystine transporter explains the cancer-specific cytotoxicity of selenite

(2009) E. Olm et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Simple and Efficient Strategy To Enhance the Antioxidant Activities of Amino-Substituted Glutathione Peroxidase Mimics

(2008) Krishna P. Bhabak et al.   CHEMISTRY-A EUROPEAN JOURNAL

Selenocystine Induces S-Phase Arrest and Apoptosis in Human Breast Adenocarcinoma MCF-7 Cells by Modulating ERK and Akt Phosphorylation

(2008) Tianfeng Chen et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Selenoproteins

(2008) Jun Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selenium Compounds and Apoptotic Modulation: A New Perspective in Cancer Therapy

(2008) Carmen Sanmartin et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY