Cigarette smoke enhances oncogene addiction to c-MET and desensitizes EGFR-expressing non-small cell lung cancer to EGFR TKIs

Stress hormones promote EGFR inhibitor resistance in NSCLC: Implications for combinations with β-blockers

(2017) Monique B. Nilsson et al.   Science Translational Medicine

Comparative Network Analysis of Patients with Non-Small Cell Lung Cancer and Smokers for Representing Potential Therapeutic Targets

(2017) Mehrdad Pazhouhandeh et al.   Scientific Reports

Cancer statistics, 2016

(2016) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Smoking-associated lung cancer prevention by blockade of the beta-adrenergic receptor-mediated insulin-like growth factor receptor activation

(2016) Hye-Young Min et al.   Oncotarget

The Efficacy and Risk Profile of c-Met inhibitors in Non-small Cell Lung Cancer: a Meta-analysis

(2016) Sa Ye et al.   Scientific Reports

MicroRNA-206: Effective Inhibition of Gastric Cancer Progression through the c-Met Pathway

(2015) Zhiqiang Zheng et al.   PLoS One

New immunotherapies targeting the PD-1 pathway

(2015) Jordan M. Chinai et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Targeting the degradation of AXL receptor tyrosine kinase to overcome resistance in gefitinib-resistant non-small cell lung cancer

(2015) Song Yi Bae et al.   Oncotarget

Overcoming resistance to targeted therapies in NSCLC: current approaches and clinical application

(2015) Paolo Maione et al.   Therapeutic Advances in Medical Oncology

RET/PTC1-Driven Neoplastic Transformation and Proinvasive Phenotype of Human Thyrocytes Involve Met Induction and β-Catenin Nuclear Translocation

(2015) Giuliana Cassinelli et al.   NEOPLASIA

Regulation of HGF Expression by ΔEGFR-Mediated c-Met Activation in Glioblastoma Cells

(2015) Jeannine Garnett et al.   NEOPLASIA

Significance of c-MET overexpression in cytotoxic anticancer drug-resistant small-cell lung cancer cells

(2014) Hiroaki Ozasa et al.   CANCER SCIENCE

Expression of hepatocyte growth factor and c-Met in non-small-cell lung cancer and association with lymphangiogenesis

(2014) NAN ZHANG et al.   Molecular Medicine Reports

Prognostic Value of MET Gene Copy Number and Protein Expression in Patients with Surgically Resected Non-Small Cell Lung Cancer: A Meta-Analysis of Published Literatures

(2014) Baoping Guo et al.   PLoS One

MicroRNA-185 inhibits proliferation by targeting c-Met in human breast cancer cells

(2014) PEIFEN FU et al.   Experimental and Therapeutic Medicine

MicroRNA-101 suppresses motility of bladder cancer cells by targeting c-Met

(2013) Zhenghui Hu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Association of integrin beta1 and c-MET in mediating EGFR TKI gefitinib resistance in non-small cell lung cancer

(2013) Lixia Ju et al.   Cancer Cell International

Tobacco specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone suppresses a newly identified anti-tumor IGFBP-3/IGFBP-3R system in lung cancer cells

(2013) Aki Harada et al.   LUNG CANCER

Met Is the Most Frequently Amplified Gene in Endometriosis-Associated Ovarian Clear Cell Adenocarcinoma and Correlates with Worsened Prognosis

(2013) Yoriko Yamashita et al.   PLoS One

Transcriptional regulation of the MET receptor tyrosine kinase gene by MeCP2 and sex-specific expression in autism and Rett syndrome

(2013) J T Plummer et al.   Translational Psychiatry

Lung carcinogenesis by tobacco smoke

(2012) Stephen S. Hecht   INTERNATIONAL JOURNAL OF CANCER

Molecular Predictors of EGFR-TKI Sensitivity in Advanced Non–small Cell Lung Cancer

(2012) Xiaozhu Zhang et al.   International Journal of Medical Sciences

Frequent Gene Amplification Predicts Poor Prognosis in Gastric Cancer

(2012) Jing Shi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MET Signaling: Novel Targeted Inhibition and Its Clinical Development in Lung Cancer

(2012) Yan Feng et al.   Journal of Thoracic Oncology

Non-Small Cell Lung Cancer: Epidemiology, Risk Factors, Treatment, and Survivorship

(2012) Julian R. Molina et al.   MAYO CLINIC PROCEEDINGS

Mitogen- and Stress-Activated Kinase 1 (MSK1) Regulates Cigarette Smoke-Induced Histone Modifications on NF-κB-dependent Genes

(2012) Isaac K. Sundar et al.   PLoS One

Cigarette Smoking Decreases Global MicroRNA Expression in Human Alveolar Macrophages

(2012) Joel W. Graff et al.   PLoS One

Lung Cancer Epidemiology, Risk Factors, and Prevention

(2012) Patricia de Groot et al.   RADIOLOGIC CLINICS OF NORTH AMERICA

Lung-Targeted Overexpression of the NF-κB Member RelB Inhibits Cigarette Smoke–Induced Inflammation

(2011) David H. McMillan et al.   AMERICAN JOURNAL OF PATHOLOGY

Cigarette smoking induces overexpression of c-Met receptor in microvessels of oral lichen planus

(2011) Sebastian K. Kłosek et al.   Archives of Medical Science

Differential roles of trans-phosphorylated EGFR, HER2, HER3 and RET as heterodimerisation partners of MET in lung cancer with MET amplification

(2011) J Tanizaki et al.   BRITISH JOURNAL OF CANCER

Clinical Implications of High MET Gene Dosage in Non-Small Cell Lung Cancer Patients without Previous Tyrosine Kinase Inhibitor Treatment

(2011) Ya-Ting Chen et al.   Journal of Thoracic Oncology

LKB1/PEA3/ΔNp63 Pathway Regulates PTGS-2 (COX-2) Transcription in Lung Cancer Cells Upon Cigarette Smoke Exposure

(2011) Edward A. Ratovitski   Oxidative Medicine and Cellular Longevity

Hazardous Compounds in Tobacco Smoke

(2011) Reinskje Talhout et al.   International Journal of Environmental Research and Public Health

An overview of the c-MET signaling pathway

(2011) Shawna Leslie Organ et al.   Therapeutic Advances in Medical Oncology

NNK-Induced Lung Tumors: A Review of Animal Model

(2011) Hua-Chuan Zheng et al.   Journal of Oncology

The tobacco-specific carcinogen NNK induces DNA methyltransferase 1 accumulation and tumor suppressor gene hypermethylation in mice and lung cancer patients

(2010) Ruo-Kai Lin et al.   JOURNAL OF CLINICAL INVESTIGATION

Activation of MET by Gene Amplification or by Splice Mutations Deleting the Juxtamembrane Domain in Primary Resected Lung Cancers

(2010) Ryoichi Onozato et al.   Journal of Thoracic Oncology

High MET Gene Copy Number Leads to Shorter Survival in Patients with Non-small Cell Lung Cancer

(2010) Heounjeong Go et al.   Journal of Thoracic Oncology

4-Methylnitrosamino-1-3-pyridyl-1-butanone (NNK) promotes lung cancer cell survival by stimulating thromboxane A2 and its receptor

(2010) R-Y Huang et al.   ONCOGENE

MET molecular mechanisms and therapies in lung cancer

(2010) Ryan E. Lawrence et al.   Cell Adhesion & Migration

Ethnic Differences and Functional Analysis of MET Mutations in Lung Cancer

(2009) S. Krishnaswamy et al.   CLINICAL CANCER RESEARCH

IncreasedMETGene Copy Number Negatively Affects Survival of Surgically Resected Non–Small-Cell Lung Cancer Patients

(2009) Federico Cappuzzo et al.   JOURNAL OF CLINICAL ONCOLOGY

MET Gene Copy Number in Non-small Cell Lung Cancer: Molecular Analysis in a Targeted Tyrosine Kinase Inhibitor Naïve Cohort

(2009) Michèle Beau-Faller et al.   Journal of Thoracic Oncology

Activating and resistance mutations of EGFR in non-small-cell lung cancer: role in clinical response to EGFR tyrosine kinase inhibitors

(2009) A F Gazdar   ONCOGENE

Crosstalk in Met receptor oncogenesis

(2009) Andrea Z. Lai et al.   TRENDS IN CELL BIOLOGY

Tobacco smoke: Unraveling a controversial subject

(2008) Anja Thielen et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Gefitinib versus docetaxel in previously treated non-small-cell lung cancer (INTEREST): a randomised phase III trial

(2008) Edward S Kim et al.   LANCET

Evidence for efficient phosphorylation of EGFR and rapid endocytosis of phosphorylated EGFR via the early/late endocytic pathway in a gefitinib-sensitive non-small cell lung cancer cell line

(2008) Yukio Nishimura et al.   Molecular Cancer

Comparison of aspects of smoking among the four histological types of lung cancer

(2008) S A Kenfield et al.   TOBACCO CONTROL

Lung Cancer Occurrence in Never-Smokers: An Analysis of 13 Cohorts and 22 Cancer Registry Studies

(2008) Michael J Thun et al.   PLOS MEDICINE

The role of polycyclic aromatic hydrocarbon–DNA adducts in inducing mutations in mouse skin

(2007) Dhrubajyoti Chakravarti et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS