Transcriptional regulation of the MET receptor tyrosine kinase gene by MeCP2 and sex-specific expression in autism and Rett syndrome

An AT-Hook Domain in MeCP2 Determines the Clinical Course of Rett Syndrome and Related Disorders

(2013) Steven Andrew Baker et al.   CELL

Rare Complete Knockouts in Humans: Population Distribution and Significant Role in Autism Spectrum Disorders

(2013) Elaine T. Lim et al.   NEURON

Autism Risk GeneMETVariation and Cortical Thickness in Typically Developing Children and Adolescents

(2012) Alexis Hedrick et al.   Autism Research

SIRT1-mediated deacetylation of MeCP2 contributes to BDNF expression

(2012) Loredana Zocchi et al.   Epigenetics

Gastrointestinal and Nutritional Problems Occur Frequently Throughout Life in Girls and Women With Rett Syndrome

(2012) Kathleen J. Motil et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

De novo mutations revealed by whole-exome sequencing are strongly associated with autism

(2012) Stephan J. Sanders et al.   NATURE

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

NMDA Receptor Regulation Prevents Regression of Visual Cortical Function in the Absence of Mecp2

(2012) Severine Durand et al.   NEURON

Transcriptional Architecture of the Primate Neocortex

(2012) Amy Bernard et al.   NEURON

Autism-Associated Promoter Variant in MET Impacts Functional and Structural Brain Networks

(2012) Jeffrey D. Rudie et al.   NEURON

A Noncoding RNA Antisense to Moesin at 5p14.1 in Autism

(2012) T. Kerin et al.   Science Translational Medicine

Autism genetics: searching for specificity and convergence

(2012) Jamee M Berg et al.   GENOME BIOLOGY

Common genetic variants, acting additively, are a major source of risk for autism

(2012) Lambertus Klei et al.   Molecular Autism

The Role of MeCP2 in the Brain

(2011) Jacky Guy et al.   Annual Review of Cell and Developmental Biology

Rett Syndrome

(2011) Alan K. Percy   ARCHIVES OF NEUROLOGY

Synaptic microcircuit dysfunction in genetic models of neurodevelopmental disorders: focus on Mecp2 and Met

(2011) Gordon MG Shepherd et al.   CURRENT OPINION IN NEUROBIOLOGY

Risk factors for autism: translating genomic discoveries into diagnostics

(2011) Stephen W. Scherer et al.   HUMAN GENETICS

A new synaptic player leading to autism risk: Met receptor tyrosine kinase

(2011) Matthew C. Judson et al.   Journal of Neurodevelopmental Disorders

Circuit-Specific Intracortical Hyperconnectivity in Mice with Deletion of the Autism-Associated Met Receptor Tyrosine Kinase

(2011) S. Qiu et al.   JOURNAL OF NEUROSCIENCE

Regulation of MET by FOXP2, Genes Implicated in Higher Cognitive Dysfunction and Autism Risk

(2011) Z. Mukamel et al.   JOURNAL OF NEUROSCIENCE

Transcriptomic analysis of autistic brain reveals convergent molecular pathology

(2011) Irina Voineagu et al.   NATURE

The conundrums of understanding genetic risks for autism spectrum disorders

(2011) Matthew W State et al.   NATURE NEUROSCIENCE

Rare De Novo and Transmitted Copy-Number Variation in Autistic Spectrum Disorders

(2011) Dan Levy et al.   NEURON

Rare De Novo Variants Associated with Autism Implicate a Large Functional Network of Genes Involved in Formation and Function of Synapses

(2011) Sarah R. Gilman et al.   NEURON

Genome-Wide Activity-Dependent MeCP2 Phosphorylation Regulates Nervous System Development and Function

(2011) Sonia Cohen et al.   NEURON

The Many Faces of MeCP2

(2011) Jacqueline F McGinty   NEUROPSYCHOPHARMACOLOGY

Olfactory neuroepithelium-derived neural progenitor cells as a model system for investigating the molecular mechanisms of neuropsychiatric disorders

(2011) Oleg V. Evgrafov et al.   PSYCHIATRIC GENETICS

Association of a MET genetic variant with autism-associated maternal autoantibodies to fetal brain proteins and cytokine expression

(2011) L Heuer et al.   Translational Psychiatry

TheMECP2duplication syndrome

(2010) Melissa B. Ramocki et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

The autism risk genes MET and PLAUR differentially impact cortical development

(2010) Kathie L. Eagleson et al.   Autism Research

Downstream targets of methyl CpG binding protein 2 and their abnormal expression in the frontal cortex of the human Rett syndrome brain

(2010) Joanne H Gibson et al.   BMC NEUROSCIENCE

Conserved Subcortical and Divergent Cortical Expression of Proteins Encoded by Orthologs of the Autism Risk Gene MET

(2010) Matthew C. Judson et al.   CEREBRAL CORTEX

Cell cloning-based transcriptome analysis in Rett patients: relevance to the pathogenesis of Rett syndrome of new human MeCP2 target genes

(2010) J. Nectoux et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Evidence of cell-nonautonomous changes in dendrite and dendritic spine morphology in the met-signaling-deficient mouse forebrain

(2010) Matthew C. Judson et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Neuronal MeCP2 Is Expressed at Near Histone-Octamer Levels and Globally Alters the Chromatin State

(2010) Peter J. Skene et al.   MOLECULAR CELL

MET signalling: principles and functions in development, organ regeneration and cancer

(2010) Livio Trusolino et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Further evidence for the role of MET in autism susceptibility

(2010) Ismail Thanseem et al.   NEUROSCIENCE RESEARCH

Prenatal Polycyclic Aromatic Hydrocarbon Exposure Leads to Behavioral Deficits and Downregulation of Receptor Tyrosine Kinase, MET

(2010) Liu Sheng et al.   TOXICOLOGICAL SCIENCES

Hypomethylation of a LINE-1 Promoter Activates an Alternate Transcript of the MET Oncogene in Bladders with Cancer

(2010) Erika M. Wolff et al.   PLoS Genetics

Advances in Autism

(2009) Daniel H. Geschwind   Annual Review of Medicine

Further evidence that the rs1858830 C variant in the promoter region of theMETgene is associated with autistic disorder

(2009) Pamela B. Jackson et al.   Autism Research

Genetic advances in autism: heterogeneity and convergence on shared pathways

(2009) Brent R Bill et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

MeCP2 functions largely cell-autonomously, but also non-cell-autonomously, in neuronal maturation and dendritic arborization of cortical pyramidal neurons

(2009) Noriyuki Kishi et al.   EXPERIMENTAL NEUROLOGY

Mouse models of MeCP2 disorders share gene expression changes in the cerebellum and hypothalamus

(2009) Shay Ben-Shachar et al.   HUMAN MOLECULAR GENETICS

PAX6 Is Expressed in Pancreatic Cancer and Actively Participates in Cancer Progression through Activation of the MET Tyrosine Kinase Receptor Gene

(2009) Joseph B. Mascarenhas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct Genetic Risk Based on Association of MET in Families With Co-occurring Autism and Gastrointestinal Conditions

(2009) D. B. Campbell et al.   PEDIATRICS

Genetic evidence implicating multiple genes in the MET receptor tyrosine kinase pathway in autism spectrum disorder

(2008) Daniel B. Campbell et al.   Autism Research

The methyl-CpG-binding protein MeCP2 and neurological disease

(2008) Adrian Bird   BIOCHEMICAL SOCIETY TRANSACTIONS

MET and autism susceptibility: family and case–control studies

(2008) Inês Sousa et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Reciprocal co-regulation of EGR2 and MECP2 is disrupted in Rett syndrome and autism

(2008) Susan E. Swanberg et al.   HUMAN MOLECULAR GENETICS

MeCP2, a Key Contributor to Neurological Disease, Activates and Represses Transcription

(2008) M. Chahrour et al.   SCIENCE