Mice Fed a High-Cholesterol Diet Supplemented with Quercetin-3-Glucoside Show Attenuated Hyperlipidemia and Hyperinsulinemia Associated with Differential Regulation of PCSK9 and LDLR in their Liver and Pancreas
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Title
Mice Fed a High-Cholesterol Diet Supplemented with Quercetin-3-Glucoside Show Attenuated Hyperlipidemia and Hyperinsulinemia Associated with Differential Regulation of PCSK9 and LDLR in their Liver and Pancreas
Authors
Keywords
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Journal
MOLECULAR NUTRITION & FOOD RESEARCH
Volume 62, Issue 9, Pages 1700729
Publisher
Wiley
Online
2018-02-03
DOI
10.1002/mnfr.201700729
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Note: Only part of the references are listed.- Protective effect of quercetin on high-fat diet-induced non-alcoholic fatty liver disease in mice is mediated by modulating intestinal microbiota imbalance and related gut-liver axis activation
- (2017) David Porras et al. FREE RADICAL BIOLOGY AND MEDICINE
- Quercetin protects against atherosclerosis by inhibiting dendritic cell activation
- (2017) Weiqun Lin et al. MOLECULAR NUTRITION & FOOD RESEARCH
- PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study
- (2017) Amand F Schmidt et al. Lancet Diabetes & Endocrinology
- Cholesterol oxidation products and their biological importance
- (2016) Waldemar Kulig et al. CHEMISTRY AND PHYSICS OF LIPIDS
- Isoquercetin Ameliorates Cerebral Impairment in Focal Ischemia Through Anti-Oxidative, Anti-Inflammatory, and Anti-Apoptotic Effects in Primary Culture of Rat Hippocampal Neurons and Hippocampal CA1 Region of Rats
- (2016) Cai-Ping Wang et al. MOLECULAR NEUROBIOLOGY
- Variation in PCSK9 and HMGCR and Risk of Cardiovascular Disease and Diabetes
- (2016) Brian A. Ference et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cholesterol in Pancreatic β-Cell Death and Dysfunction
- (2016) Rajib Paul et al. PANCREAS
- A Low Dose of Dietary Quercetin Fails to Protect against the Development of an Obese Phenotype in Mice
- (2016) Reilly T. Enos et al. PLoS One
- Quercetin: A flavonol with multifaceted therapeutic applications?
- (2015) Gabriele D'Andrea FITOTERAPIA
- Quercetin reduces obesity-induced hepatosteatosis by enhancing mitochondrial oxidative metabolism via heme oxygenase-1
- (2015) Chu-Sook Kim et al. Nutrition & Metabolism
- The molecular basis of the antidiabetic action of quercetin in cultured skeletal muscle cells and hepatocytes
- (2015) PierreS Haddad et al. Pharmacognosy Magazine
- Quercetin and related polyphenols: new insights and implications for their bioactivity and bioavailability
- (2015) Kyuichi Kawabata et al. Food & Function
- Estimated Daily Intake and Seasonal Food Sources of Quercetin in Japan
- (2015) Haruno Nishimuro et al. Nutrients
- GLUT2, glucose sensing and glucose homeostasis
- (2014) Bernard Thorens DIABETOLOGIA
- Isoquercitrin: Pharmacology, toxicology, and metabolism
- (2014) Kateřina Valentová et al. FOOD AND CHEMICAL TOXICOLOGY
- Quercetin reduces obesity-associated ATM infiltration and inflammation in mice: a mechanism including AMPKα1/SIRT1
- (2014) Jing Dong et al. JOURNAL OF LIPID RESEARCH
- Extract of okra lowers blood glucose and serum lipids in high-fat diet-induced obese C57BL/6 mice
- (2014) Shengjie Fan et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Effects of resveratrol and other polyphenols in hepatic steatosis
- (2014) Leixuri Aguirre WORLD JOURNAL OF GASTROENTEROLOGY
- Variable effects of gender and Western diet on lipid and glucose homeostasis in aged PCSK9-deficient C57BL/6 mice 性别与西方饮食对CSK9基因缺陷的PC57BL/6老龄小鼠的脂质以及葡萄糖内稳态的不同影响
- (2014) Majambu Mbikay et al. Journal of Diabetes
- Quercetin-3-glucoside increases low-density lipoprotein receptor (LDLR) expression, attenuates proprotein convertase subtilisin/kexin 9 (PCSK9) secretion, and stimulates LDL uptake by Huh7 human hepatocytes in culture
- (2014) Majambu Mbikay et al. FEBS Open Bio
- Dietary quercetin attenuates oxidant-induced endothelial dysfunction and atherosclerosis in apolipoprotein E knockout mice fed a high-fat diet: A critical role for heme oxygenase-1
- (2013) Yu Shen et al. FREE RADICAL BIOLOGY AND MEDICINE
- Different Conformation of Thiol Protease Inhibitor During Amyloid Formation: Inhibition by Curcumin and Quercetin
- (2013) Mohd Shahnawaz Khan et al. JOURNAL OF FLUORESCENCE
- Quercetin differently regulates insulin-mediated glucose transporter 4 translocation under basal and inflammatory conditions in adipocytes
- (2013) Manli Xu et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Proprotein Convertases Subtilisin/Kexin Type 9, an enzyme turned escort protein: Hepatic and extra hepatic functions (第9型前蛋白转换酶-枯草溶菌素/蛋白酶K,一种酶转变的护送蛋白:在肝脏与肝外的功能)
- (2013) Majambu Mbikay et al. Journal of Diabetes
- Gene Inactivation of Proprotein Convertase Subtilisin/Kexin Type 9 Reduces Atherosclerosis in Mice
- (2012) Maxime Denis et al. CIRCULATION
- Transcriptomic and Metabonomic Profiling Reveal Synergistic Effects of Quercetin and Resveratrol Supplementation in High Fat Diet Fed Mice
- (2012) Mingmei Zhou et al. JOURNAL OF PROTEOME RESEARCH
- Quercetin Reduces High-Fat Diet-Induced Fat Accumulation in the Liver by Regulating Lipid Metabolism Genes
- (2012) Chang Hwa Jung et al. PHYTOTHERAPY RESEARCH
- Novel Loss-of-Function PCSK9 Variant Is Associated with Low Plasma LDL Cholesterol in a French-Canadian Family and with Impaired Processing and Secretion in Cell Culture
- (2011) J. Mayne et al. CLINICAL CHEMISTRY
- Quercetin binds to calcineurin at a similar region to cyclosporin A and tacrolimus
- (2011) Hong Lei et al. FOOD CHEMISTRY
- Binding of Quercetin to Lysozyme as Probed by Spectroscopic Analysis and Molecular Simulation
- (2011) Gongke Wang et al. JOURNAL OF FLUORESCENCE
- Antidiabetic activity of isoquercetin in diabetic KK -Ay mice
- (2011) Rui Zhang et al. Nutrition & Metabolism
- Leucine 10 allelic variant in signal peptide of PCSK9 increases the LDL cholesterol-lowering effect of statins in patients with familial hypercholesterolaemia
- (2011) L. Pisciotta et al. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
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- (2009) Joseph L. Goldstein et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- PCSK9 is expressed in pancreatic δ-cells and does not alter insulin secretion
- (2009) Cédric Langhi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- PCSK9-deficient mice exhibit impaired glucose tolerance and pancreatic islet abnormalities
- (2009) Majambu Mbikay et al. FEBS LETTERS
- Dietary quercetin alleviates diabetic symptoms and reduces streptozotocin-induced disturbance of hepatic gene expression in mice
- (2009) Msauko Kobori et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Proprotein convertase subtilisin/kexin type 9 (PCSK9): Hepatocyte-specific low-density lipoprotein receptor degradation and critical role in mouse liver regeneration
- (2008) Ahmed Zaid et al. HEPATOLOGY
- Plasma PCSK9 levels are significantly modified by statins and fibrates in humans
- (2008) Janice Mayne et al. Lipids in Health and Disease
- Apple polyphenols inhibit plasma CETP activity and reduce the ratio of non-HDL to HDL cholesterol
- (2008) Cheuk Kai Lam et al. MOLECULAR NUTRITION & FOOD RESEARCH
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