Lipotoxic Effects of Palmitic Acid on Astrocytes Are Associated with Autophagy Impairment

Sex differences in the neuroendocrine control of metabolism and the implication of astrocytes

(2018) Julie A. Chowen et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Palmitate mediated diacylglycerol accumulation causes endoplasmic reticulum stress, Plin2 degradation, and cell death in H9C2 cardiomyoblasts

(2017) Ali Akoumi et al.   EXPERIMENTAL CELL RESEARCH

Sex differences in the phagocytic and migratory activity of microglia and their impairment by palmitic acid

(2017) Natalia Yanguas-Casás et al.   GLIA

Monitoring and Measuring Autophagy

(2017) Saori R. Yoshii et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Autophagy: The spotlight for cellular stress responses

(2017) Palaniyandi Ravanan et al.   LIFE SCIENCES

Tibolone Preserves Mitochondrial Functionality and Cell Morphology in Astrocytic Cells Treated with Palmitic Acid

(2017) Yeimy González-Giraldo et al.   MOLECULAR NEUROBIOLOGY

Obesity and insulin resistance are associated with reduced activity in core memory regions of the brain

(2017) Lucy G. Cheke et al.   NEUROPSYCHOLOGIA

Behavioral changes in male mice fed a high-fat diet are associated with IL-1β expression in specific brain regions

(2017) Camila P. Almeida-Suhett et al.   PHYSIOLOGY & BEHAVIOR

Estradiol Uses Different Mechanisms in Astrocytes from the Hippocampus of Male and Female Rats to Protect against Damage Induced by Palmitic Acid

(2017) Laura M. Frago et al.   Frontiers in Molecular Neuroscience

Non-Neuronal Cells in the Hypothalamic Adaptation to Metabolic Signals

(2017) Alejandra Freire-Regatillo et al.   Frontiers in Endocrinology

Assessment of Autophagy in Neurons and Brain Tissue

(2017) Irene Benito-Cuesta et al.   Cells

Oxidative stress-mediated NFκB phosphorylation upregulates p62/SQSTM1 and promotes retinal pigmented epithelial cell survival through increased autophagy

(2017) Chunjuan Song et al.   PLoS One

Palmitic Acid Reduces Circulating Bone Formation Markers in Obese Animals and Impairs Osteoblast Activity via C16-Ceramide Accumulation

(2016) Ahmad Alsahli et al.   CALCIFIED TISSUE INTERNATIONAL

Lysosome acidification by photoactivated nanoparticles restores autophagy under lipotoxicity

(2016) Kyle M. Trudeau et al.   JOURNAL OF CELL BIOLOGY

Blood–brain barrier breakdown promotes macrophage infiltration and cognitive impairment in leptin receptor-deficient mice

(2016) Alexis M Stranahan et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Thiamine Deficiency and Neurodegeneration: the Interplay Among Oxidative Stress, Endoplasmic Reticulum Stress, and Autophagy

(2016) Dexiang Liu et al.   MOLECULAR NEUROBIOLOGY

Recent insights into cell death and autophagy

(2015) Brent E. Fitzwalter et al.   FEBS Journal

The sexual dimorphism of obesity

(2015) Biff F. Palmer et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

C1q/TNF-Related Protein 9 (CTRP9) attenuates hepatic steatosis via the autophagy-mediated inhibition of endoplasmic reticulum stress

(2015) Tae Woo Jung et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Saturated Fatty Acids Modulate Autophagy’s Proteins in the Hypothalamus

(2015) Mariana Portovedo et al.   PLoS One

PGC−1α Promoter Methylation in Parkinson’s Disease

(2015) Xiaomin Su et al.   PLoS One

Inhibition of Autophagic Turnover in β-Cells by Fatty Acids and Glucose Leads to Apoptotic Cell Death

(2014) Shakeel U. R. Mir et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Palmitic acid-induced lipotoxicity and protection by (+)-catechin in rat cortical astrocytes

(2014) Kar-Lok Wong et al.   Pharmacological Reports

Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD

(2014) Á González-Rodríguez et al.   Cell Death & Disease

Hypothalamic PGC-1α Protects Against High-Fat Diet Exposure by Regulating ERα

(2014) Eugenia Morselli et al.   Cell Reports

RNA Sequencing Identifies Dysregulation of the Human Pancreatic Islet Transcriptome by the Saturated Fatty Acid Palmitate

(2013) Miriam Cnop et al.   DIABETES

Mouse strain-dependent variation in obesity and glucose homeostasis in response to high-fat feeding

(2013) M. K. Montgomery et al.   DIABETOLOGIA

Estradiol and Testosterone Regulate Arginine-Vasopressin Expression in SH-SY5Y Human Female Neuroblastoma Cells Through Estrogen Receptors-α and -β

(2013) Daniela Grassi et al.   ENDOCRINOLOGY

Sex Differences and Effects of Estrogenic Compounds on the Expression of Inflammatory Molecules by Astrocytes Exposed to the Insecticide Dimethoate

(2013) Mariana Astiz et al.   NEUROTOXICITY RESEARCH

The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression

(2013) Wafa B’chir et al.   NUCLEIC ACIDS RESEARCH

Saturated long-chain fatty acids activate inflammatory signaling in astrocytes

(2012) Sunita Gupta et al.   JOURNAL OF NEUROCHEMISTRY

17β-Oestradiol Anti-Inflammatory Effects in Primary Astrocytes Require Oestrogen Receptor β-Mediated Neuroglobin Up-Regulation

(2012) E. De Marinis et al.   JOURNAL OF NEUROENDOCRINOLOGY

Palmitate-activated astrocytes via serine palmitoyltransferase increase BACE1 in primary neurons by sphingomyelinases

(2012) Li Liu et al.   NEUROBIOLOGY OF AGING

Sex and estradiol influence glial pro-inflammatory responses to lipopolysaccharide in rats

(2012) Lisa C. Loram et al.   PSYCHONEUROENDOCRINOLOGY

Fatty Acids Suppress Autophagic Turnover in β-Cells

(2011) Guy Las et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Obesity is associated with hypothalamic injury in rodents and humans

(2011) Joshua P. Thaler et al.   JOURNAL OF CLINICAL INVESTIGATION

Notch/Neurogenin 3 Signalling is Involved in the Neuritogenic Actions of Oestradiol in Developing Hippocampal Neurones

(2011) I. Ruiz-Palmero et al.   JOURNAL OF NEUROENDOCRINOLOGY

Cytoprotective effects of melatonin on astroglial cells subjected to palmitic acid treatment in vitro

(2011) Zhen Wang et al.   JOURNAL OF PINEAL RESEARCH

Obesity and Dyslipidemia

(2011) Remco Franssen et al.   MEDICAL CLINICS OF NORTH AMERICA

Sex differences in the inflammatory response of primary astrocytes to lipopolysaccharide

(2011) María Santos-Galindo et al.   Biology of Sex Differences

Increased Brain Fatty Acid Uptake in Metabolic Syndrome

(2010) A. Karmi et al.   DIABETES

Autophagy and Metabolism

(2010) J. D. Rabinowitz et al.   SCIENCE

Meta-Analysis of Alzheimer's Disease Risk with Obesity, Diabetes, and Related Disorders

(2009) Louis A. Profenno et al.   BIOLOGICAL PSYCHIATRY

Brain structure and obesity

(2009) Cyrus A. Raji et al.   HUMAN BRAIN MAPPING

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE

Fatty Acid Composition of Frontal, Temporal and Parietal Neocortex in the Normal Human Brain and in Alzheimer’s Disease

(2009) Thomas Fraser et al.   NEUROCHEMICAL RESEARCH

Hypothalamic IKKβ/NF-κB and ER Stress Link Overnutrition to Energy Imbalance and Obesity

(2008) Xiaoqing Zhang et al.   CELL

Diet-induced insulin resistance impairs hippocampal synaptic plasticity and cognition in middle-aged rats

(2008) Alexis M. Stranahan et al.   HIPPOCAMPUS