Effects of Age and Estrogen on Skeletal Gene Expression in Humans as Assessed by RNA Sequencing

Osteocytes mediate the anabolic actions of canonical Wnt/β-catenin signaling in bone

(2015) Xiaolin Tu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibin at 90: From Discovery to Clinical Application, a Historical Review

(2014) Yogeshwar Makanji et al.   ENDOCRINE REVIEWS

Romosozumab in Postmenopausal Women with Low Bone Mineral Density

(2014) Michael R. McClung et al.   NEW ENGLAND JOURNAL OF MEDICINE

Chromosome 19 open reading frame 80 is upregulated by thyroid hormone and modulates autophagy and lipid metabolism

(2013) Yi-Hsin Tseng et al.   Autophagy

Effects of age on bone mRNA levels of sclerostin and other genes relevant to bone metabolism in humans

(2013) Matthew M. Roforth et al.   BONE

RETRACTED: Betatrophin: A Hormone that Controls Pancreatic β Cell Proliferation

(2013) Peng Yi et al.   CELL

An RNA-seq protocol to identify mRNA expression changes in mouse diaphyseal bone: Applications in mice with bone property alteringLrp5mutations

(2013) Ugur M Ayturk et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Association of Circulating Sclerostin With Bone Mineral Mass, Microstructure, and Turnover Biochemical Markers in Healthy Elderly Men and Women

(2013) Claire Durosier et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Effects of Estrogen on Bone mRNA Levels of Sclerostin and Other Genes Relevant to Bone Metabolism in Postmenopausal Women

(2013) Koji Fujita et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Sema3A regulates bone-mass accrual through sensory innervations

(2013) Toru Fukuda et al.   NATURE

WNT signaling in bone homeostasis and disease: from human mutations to treatments

(2013) Roland Baron et al.   NATURE MEDICINE

Isolation and characterization of human osteoblasts from needle biopsies without in vitro culture

(2013) K. Fujita et al.   OSTEOPOROSIS INTERNATIONAL

p21 Both Attenuates and Drives Senescence and Aging in BubR1 Progeroid Mice

(2013) Darren J. Baker et al.   Cell Reports

RSeQC: quality control of RNA-seq experiments

(2012) Liguo Wang et al.   BIOINFORMATICS

Removing technical variability in RNA-seq data using conditional quantile normalization

(2012) K. D. Hansen et al.   BIOSTATISTICS

Pathogenesis of Age-Related Bone Loss in Humans

(2012) S. Khosla   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Activin Receptor Signaling: A Potential Therapeutic Target for Osteoporosis

(2012) Sutada Lotinun et al.   Current Molecular Pharmacology

Patients with sclerosteosis and disease carriers: Human models of the effect of sclerostin on bone turnover

(2011) Antoon H van Lierop et al.   JOURNAL OF BONE AND MINERAL RESEARCH

R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/ -catenin signaling

(2011) K. S. Carmon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A soluble activin receptor Type IIA fusion protein (ACE-011) increases bone mass via a dual anabolic-antiresorptive effect in Cynomolgus monkeys

(2010) Sutada Lotinun et al.   BONE

Patients with primary hyperparathyroidism have lower circulating sclerostin levels than euparathyroid controls

(2010) A H van Lierop et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Regulation of circulating sclerostin levels by sex steroids in women and in men

(2010) Ulrike IL Mödder et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Relation of age, gender, and bone mass to circulating sclerostin levels in women and men

(2010) Ulrike I Mödder et al.   JOURNAL OF BONE AND MINERAL RESEARCH

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Ubiquitous overexpression of Hey1 transcription factor leads to osteopenia and chondrocyte hypertrophy in bone

(2009) Rishard Salie et al.   BONE

Treatment with a soluble receptor for activin improves bone mass and structure in the axial and appendicular skeleton of female cynomolgus macaques (Macaca fascicularis)

(2009) Roberto José Fajardo et al.   BONE

Regulation of osteoblastogenesis and osteoclastogenesis by the other reproductive hormones, Activin and Inhibin

(2009) Kristy M. Nicks et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Single-Dose, Randomized, Double-Blind, Placebo-Controlled Study of ACE-011 (ActRIIA-IgG1) in Postmenopausal Women*

(2008) Jon Ruckle et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Building bone to reverse osteoporosis and repair fractures

(2008) Sundeep Khosla et al.   JOURNAL OF CLINICAL INVESTIGATION

Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation

(2008) Matthew J Hilton et al.   NATURE MEDICINE

A soluble activin Type IIA receptor induces bone formation and improves skeletal integrity

(2008) R. S. Pearsall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA