Human keratin 8 variants promote mouse acetaminophen hepatotoxicity coupled with c-jun amino-terminal kinase activation and protein adduct formation

Pathogenesis of Idiosyncratic Drug-Induced Liver Injury and Clinical Perspectives

(2014) Robert J. Fontana   GASTROENTEROLOGY

Post-translational modifications of intermediate filament proteins: mechanisms and functions

(2014) Natasha T. Snider et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Networking galore: intermediate filaments and cell migration

(2013) Byung-Min Chung et al.   CURRENT OPINION IN CELL BIOLOGY

The expanding significance of keratin intermediate filaments in normal and diseased epithelia

(2012) Xiaoou Pan et al.   CURRENT OPINION IN CELL BIOLOGY

Keratins

(2012) Pavel Strnad et al.   CURRENT OPINION IN GASTROENTEROLOGY

Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: Lessons learned from acetaminophen hepatotoxicity

(2012) Hartmut Jaeschke et al.   DRUG METABOLISM REVIEWS

A Liver Full of JNK: Signaling in Regulation of Cell Function and Disease Pathogenesis, and Clinical Approaches

(2012) Ekihiro Seki et al.   GASTROENTEROLOGY

Unique amino acid signatures that are evolutionarily conserved distinguish simple-type, epidermal and hair keratins

(2012) Pavel Strnad et al.   JOURNAL OF CELL SCIENCE

Keratins and disease at a glance

(2012) Rebecca L. Haines et al.   JOURNAL OF CELL SCIENCE

Defining Keratin Protein Function in Skin Epithelia: Epidermolysis Bullosa Simplex and Its Aftermath

(2012) Pierre A. Coulombe et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Non-Coding Keratin Variants Associate with Liver Fibrosis Progression in Patients with Hemochromatosis

(2012) Pavel Strnad et al.   PLoS One

Paracetamol metabolism and related genetic differences

(2010) Lizi Zhao et al.   DRUG METABOLISM REVIEWS

Keratin Variants Predispose to Acute Liver Failure and Adverse Outcome: Race and Ethnic Associations

(2010) Pavel Strnad et al.   GASTROENTEROLOGY

Acute liver failure

(2010) William Bernal et al.   LANCET

Keratin variants are overrepresented in primary biliary cirrhosis and associate with disease severity

(2009) Bihui Zhong et al.   HEPATOLOGY

Keratins modulate the shape and function of hepatocyte mitochondria: a mechanism for protection from apoptosis

(2009) G.-Z. Tao et al.   JOURNAL OF CELL SCIENCE

Toward unraveling the complexity of simple epithelial keratins in human disease

(2009) M. Bishr Omary et al.   JOURNAL OF CLINICAL INVESTIGATION

Keratin Mutation Predisposes to Mouse Liver Fibrosis and Unmasks Differential Effects of the Carbon Tetrachloride and Thioacetamide Models

(2008) Pavel Strnad et al.   GASTROENTEROLOGY

Ballooned hepatocytes in steatohepatitis: The value of keratin immunohistochemistry for diagnosis

(2008) Carolin Lackner et al.   JOURNAL OF HEPATOLOGY

The Human Intermediate Filament Database: comprehensive information on a gene family involved in many human diseases

(2007) Ildiko Szeverenyi et al.   HUMAN MUTATION