Characterization of amoxicillin- and clavulanic acid-specific T cells in patients with amoxicillin-clavulanate-induced liver injury

Activation of Flucloxacillin-Specific CD8+ T-Cells With the Potential to Promote Hepatocyte Cytotoxicity in a Mouse Model

(2015) Ryan Nattrass et al.   TOXICOLOGICAL SCIENCES

T Cells Infiltrate the Liver and Kill Hepatocytes in HLA-B ∗ 57:01-Associated Floxacillin-Induced Liver Injury

(2014) Natascha Wuillemin et al.   AMERICAN JOURNAL OF PATHOLOGY

Mild Isoniazid-Induced Liver Injury in Humans Is Associated with an Increase in Th17 Cells and T Cells Producing IL-10

(2014) Imir G. Metushi et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Idiosyncratic Drug-Induced Liver Injury Is Associated With Substantial Morbidity and Mortality Within 6 Months From Onset

(2014) Robert J. Fontana et al.   GASTROENTEROLOGY

In Vitro Diagnosis of Delayed-type Drug Hypersensitivity

(2014) Dean J. Naisbitt et al.   IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA

Prospective Validation ofHLA-DRB1*07:01Allele Carriage As a Predictive Risk Factor for Lapatinib-Induced Liver Injury

(2014) Daniel J. Schaid et al.   JOURNAL OF CLINICAL ONCOLOGY

Opposing effects on immune function and skin barrier regulation by the proteasome inhibitor bortezomib in an allergen-induced eczema model

(2013) Kiran Kumar Mudnakudu Nagaraju et al.   EXPERIMENTAL DERMATOLOGY

HLA Haplotype Determines Hapten or p-i T Cell Reactivity to Flucloxacillin

(2013) N. Wuillemin et al.   JOURNAL OF IMMUNOLOGY

Therapeutic opportunities of the IL-22–IL-22R1 system

(2013) Robert Sabat et al.   NATURE REVIEWS DRUG DISCOVERY

HLA Alleles Influence the Clinical Signature of Amoxicillin-Clavulanate Hepatotoxicity

(2013) Camilla Stephens et al.   PLoS One

Human leukocyte antigen (HLA)-B*57:01-restricted activation of drug-specific T cells provides the immunological basis for flucloxacillin-induced liver injury

(2012) Manal M. Monshi et al.   HEPATOLOGY

Proteasome Inhibitor Bortezomib Ameliorates Intestinal Injury in Mice

(2012) Koichi Yanaba et al.   PLoS One

Susceptibility to Amoxicillin-Clavulanate-Induced Liver Injury Is Influenced by Multiple HLA Class I and II Alleles

(2011) M. Isabel Lucena et al.   GASTROENTEROLOGY

HLA-DQA1*02:01 Is a Major Risk Factor for Lapatinib-Induced Hepatotoxicity in Women With Advanced Breast Cancer

(2011) Colin F. Spraggs et al.   JOURNAL OF CLINICAL ONCOLOGY

Human leucocyte antigen class II genotype in susceptibility and resistance to co-amoxiclav-induced liver injury

(2010) Peter T. Donaldson et al.   JOURNAL OF HEPATOLOGY

The proteasome inhibitor bortezomib inhibits T cell-dependent inflammatory responses

(2010) Koichi Yanaba et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury

(2010) Jonathan B Singer et al.   NATURE GENETICS

Cytokine and autoantibody patterns in acute liver failure

(2009) Jinze Li et al.   Journal of Immunotoxicology

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin

(2009) Ann K Daly et al.   NATURE GENETICS

Characterisation of flucloxacillin and 5-hydroxymethyl flucloxacillin haptenated HSAin vitroandin vivo

(2009) Rosalind E. Jenkins et al.   Proteomics Clinical Applications