Human leukocyte antigen (HLA)-B*57:01-restricted activation of drug-specific T cells provides the immunological basis for flucloxacillin-induced liver injury

Abacavir induces loading of novel self-peptides into HLA-B*57

(2012) Michael A. Norcross et al.   AIDS

Hepatic recruitment of macrophages promotes nonalcoholic steatohepatitis through CCR2

(2012) Kouichi Miura et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Avidity determines T-cell reactivity in abacavir hypersensitivity

(2012) Jacqueline Adam et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire

(2012) D. A. Ostrov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Development of In Vitro Culture Methods to Characterize Primary T-Cell Responses to Drugs

(2012) Lee Faulkner et al.   TOXICOLOGICAL SCIENCES

In silico analysis of HLA associations with drug-induced liver injury: use of a HLA-genotyped DNA archive from healthy volunteers

(2012) Ana Alfirevic et al.   Genome Medicine

Shared and restricted T-cell receptor use is crucial for carbamazepine-induced Stevens-Johnson syndrome

(2011) Tai-Ming Ko et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mass Spectrometric Characterization of Circulating and Functional Antigens Derived from Piperacillin in Patients with Cystic Fibrosis

(2011) P. Whitaker et al.   JOURNAL OF IMMUNOLOGY

Managing the challenge of chemically reactive metabolites in drug development

(2011) B. Kevin Park et al.   NATURE REVIEWS DRUG DISCOVERY

HLA-A*3101 and Carbamazepine-Induced Hypersensitivity Reactions in Europeans

(2011) Mark McCormack et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genome-wide association study identifies HLA-A*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population

(2010) Takeshi Ozeki et al.   HUMAN MOLECULAR GENETICS

A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury

(2010) Jonathan B Singer et al.   NATURE GENETICS

Fulminant Liver Failure After Vancomycin in a Sulfasalazine-Induced DRESS Syndrome: Fatal Recurrence After Liver Transplantation

(2009) M. Mennicke et al.   AMERICAN JOURNAL OF TRANSPLANTATION

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin

(2009) Ann K Daly et al.   NATURE GENETICS

Characterisation of flucloxacillin and 5-hydroxymethyl flucloxacillin haptenated HSAin vitroandin vivo

(2009) Rosalind E. Jenkins et al.   Proteomics Clinical Applications

Human Leukocyte Antigen Class I-Restricted Activation of CD8+ T Cells Provides the Immunogenetic Basis of a Systemic Drug Hypersensitivity

(2008) Diana Chessman et al.   IMMUNITY