Activation of Flucloxacillin-Specific CD8+ T-Cells With the Potential to Promote Hepatocyte Cytotoxicity in a Mouse Model

T Cells Infiltrate the Liver and Kill Hepatocytes in HLA-B ∗ 57:01-Associated Floxacillin-Induced Liver Injury

(2014) Natascha Wuillemin et al.   AMERICAN JOURNAL OF PATHOLOGY

Involvement of immune- and inflammatory-related factors in flucloxacillin-induced liver injury in mice

(2014) Shohei Takai et al.   JOURNAL OF APPLIED TOXICOLOGY

Lithocholic acid feeding results in direct hepato-toxicity independent of neutrophil function in mice

(2014) Benjamin L. Woolbright et al.   TOXICOLOGY LETTERS

Identification and frequency of circulating CD4+T lymphocytes specific to Benzylpenicillin in healthy donors

(2013) C. Nhim et al.   ALLERGY

Mechanistic biomarkers provide early and sensitive detection of acetaminophen-induced acute liver injury at first presentation to hospital

(2013) Daniel J. Antoine et al.   HEPATOLOGY

HLA Haplotype Determines Hapten or p-i T Cell Reactivity to Flucloxacillin

(2013) N. Wuillemin et al.   JOURNAL OF IMMUNOLOGY

Plasma biomarkers of liver injury and inflammation demonstrate a lack of apoptosis during obstructive cholestasis in mice

(2013) Benjamin L. Woolbright et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Role of immune reactions in drug-induced liver injury (DILI)

(2012) Cynthia Ju et al.   DRUG METABOLISM REVIEWS

Eosinophils mediate the pathogenesis of halothane-induced liver injury in mice

(2012) William R. Proctor et al.   HEPATOLOGY

Human leukocyte antigen (HLA)-B*57:01-restricted activation of drug-specific T cells provides the immunological basis for flucloxacillin-induced liver injury

(2012) Manal M. Monshi et al.   HEPATOLOGY

Effects of long-term exposure of gelatinated and non-gelatinated cadmium telluride quantum dots on differentiated PC12 cells

(2012) Babu R Prasad et al.   JOURNAL OF NANOBIOTECHNOLOGY

Connecting liver and gut: Murine liver sinusoidal endothelium induces gut tropism of CD4+ T cells via retinoic acid

(2011) Katrin Neumann et al.   HEPATOLOGY

Mass Spectrometric Characterization of Circulating and Functional Antigens Derived from Piperacillin in Patients with Cystic Fibrosis

(2011) P. Whitaker et al.   JOURNAL OF IMMUNOLOGY

CD8+ T cells mediate skin allergy to amoxicillin in a mouse model

(2010) A. Rozieres et al.   ALLERGY

Gut Homing Receptors on CD8 T Cells Are Retinoic Acid Dependent and Not Maintained by Liver Dendritic or Stellate Cells

(2009) Bertus Eksteen et al.   GASTROENTEROLOGY

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin

(2009) Ann K Daly et al.   NATURE GENETICS

High-Mobility Group Box-1 Protein and Keratin-18, Circulating Serum Proteins Informative of Acetaminophen-Induced Necrosis and Apoptosis In Vivo

(2009) Daniel J. Antoine et al.   TOXICOLOGICAL SCIENCES

Skin Exposure to Weak and Moderate Contact Allergens Induces IFNγ Production by Lymph Node Cells of CD4+ T-Cell-Depleted Mice

(2008) Marc Vocanson et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY