Dasatinib Suppresses TGFβ-Mediated Epithelial–Mesenchymal Transition in Alveolar Epithelial Cells and Inhibits Pulmonary Fibrosis

Effect of dasatinib on EMT-mediated-mechanism of resistance against EGFR inhibitors in lung cancer cells

(2017) Yuichi Sesumi et al.   LUNG CANCER

Dasatinib prevent hepatic fibrosis induced by carbon tetrachloride (CCl4) via anti-inflammatory and antioxidant mechanism

(2016) Adel Mohammadalipour et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Dasatinib Reduces Lung Inflammation and Fibrosis in Acute Experimental Silicosis

(2016) Fernanda Ferreira Cruz et al.   PLoS One

Dasatinib inhibits TGFβ-induced myofibroblast differentiation through Src-SRF Pathway

(2015) Maha Abdalla et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Dasatinib attenuated bleomycin-induced pulmonary fibrosis in mice

(2015) Oznur Yilmaz et al.   GROWTH FACTORS

Dasatinib blocks transcriptional and promigratory responses to transforming growth factor-beta in pancreatic adenocarcinoma cells through inhibition of Smad signalling: implications for in vivo mode of action

(2015) Tobias Bartscht et al.   Molecular Cancer

Dasatinib Attenuates Pressure Overload Induced Cardiac Fibrosis in a Murine Transverse Aortic Constriction Model

(2015) Sundaravadivel Balasubramanian et al.   PLoS One

Overcoming EMT-associated resistance to anti-cancer drugs via Src/FAK pathway inhibition

(2015) Catherine Wilson et al.   Oncotarget

A Phase 3 Trial of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis

(2014) Talmadge E. King et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efficacy and Safety of Nintedanib in Idiopathic Pulmonary Fibrosis

(2014) Luca Richeldi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effectiveness of dasatinib in accelerated-phase chronic myeloid leukemia with p190 BCR-ABL1 and a second Philadelphia chromosome

(2014) Karen E. Rabenau et al.   Cancer Genetics

Hypoxia induces gefitinib resistance in non-small-cell lung cancer with both mutant and wild-type epidermal growth factor receptors

(2012) Kunihiko Minakata et al.   CANCER SCIENCE

Prognostic significance of fibroblastic foci in usual interstitial pneumonia and non-specific interstitial pneumonia

(2012) TAISHI HARADA et al.   RESPIROLOGY

Epithelial-Mesenchymal Interactions in Pulmonary Fibrosis

(2011) Harold A. Chapman   Annual Review of Physiology

Dasatinib as a Single Agent in Triple-Negative Breast Cancer: Results of an Open-Label Phase 2 Study

(2011) R. S. Finn et al.   CLINICAL CANCER RESEARCH

Inhibition of Src Family Kinases and Receptor Tyrosine Kinases by Dasatinib: Possible Combinations in Solid Tumors

(2011) J. C. Montero et al.   CLINICAL CANCER RESEARCH

Role of Smad2/3 and p38 MAP kinase in TGF-β1-induced epithelial-mesenchymal transition of pulmonary epithelial cells

(2010) Irina Kolosova et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Clinical and molecular evidences of epithelial to mesenchymal transition in acquired resistance to EGFR-TKIs

(2010) Jin-Haeng Chung et al.   LUNG CANCER

Antifibrotic action of pirfenidone and prednisolone: Different effects on pulmonary cytokines and growth factors in bleomycin-induced murine pulmonary fibrosis

(2008) Hisashi Oku et al.   EUROPEAN JOURNAL OF PHARMACOLOGY