Dasatinib Attenuates Pressure Overload Induced Cardiac Fibrosis in a Murine Transverse Aortic Constriction Model

Long-term outcome with dasatinib after imatinib failure in chronic-phase chronic myeloid leukemia: follow-up of a phase 3 study

(2014) N. P. Shah et al.   BLOOD

Preservation of cardiomyocytes from the adult heart

(2013) Najah Abi-Gerges et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Biomarkers of Diastolic Dysfunction and Myocardial Fibrosis: Application to Heart Failure with a Preserved Ejection Fraction

(2013) Michael R. Zile et al.   Journal of Cardiovascular Translational Research

Tyrosine kinase signaling in fibrotic disorders

(2012) Christian Beyer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Locally expressed IGF1 propeptide improves mouse heart function in induced dilated cardiomyopathy by blocking myocardial fibrosis and SRF-dependent CTGF induction

(2012) M. Touvron et al.   Disease Models & Mechanisms

β3 Integrin in Cardiac Fibroblast Is Critical for Extracellular Matrix Accumulation during Pressure Overload Hypertrophy in Mouse

(2012) Sundaravadivel Balasubramanian et al.   PLoS One

SPARC regulates collagen interaction with cardiac fibroblast cell surfaces

(2011) Brett S. Harris et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Phosphorylation of Histone H2B Serine 32 Is Linked to Cell Transformation

(2011) Andy T. Y. Lau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The kinase Pyk2 is involved in renal fibrosis by means of mechanical stretch–induced growth factor expression in renal tubules

(2011) Kazuhiro Sonomura et al.   KIDNEY INTERNATIONAL

Potential Therapeutic Targets for Cardiac Fibrosis

(2010) Andrew Leask   CIRCULATION RESEARCH

Lack of β3 Integrin Signaling Contributes to Calpain-Mediated Myocardial Cell Loss in Pressure-Overloaded Myocardium

(2010) Geetha Suryakumar et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Regulation of pro-inflammatory and pro-fibrotic factors by CCN2/CTGF in H9c2 cardiomyocytes

(2010) Xiaoyu Wang et al.   Journal of Cell Communication and Signaling

Inhibition of transforming growth factor-β signaling induces left ventricular dilation and dysfunction in the pressure-overloaded heart

(2009) Jason A. Lucas et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Pressure Overload–Induced Alterations in Fibrillar Collagen Content and Myocardial Diastolic Function

(2009) Amy D. Bradshaw et al.   CIRCULATION

New approved dasatinib regimen available for clinical use

(2009) David S Snyder   Expert Review of Anticancer Therapy

β3 Integrin-mediated ubiquitination activates survival signaling during myocardial hypertrophy

(2009) Rebecca K. Johnston et al.   FASEB JOURNAL

Development of a high-performance liquid chromatographic–mass spectrometric method for the determination of cellular levels of the tyrosine kinase inhibitors lapatinib and dasatinib

(2009) Sandra Roche et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Cardiotoxicity of Anticancer Drugs: The Need for Cardio-Oncology and Cardio-Oncological Prevention

(2009) Adriana Albini et al.   JNCI-Journal of the National Cancer Institute

In vivo administration of calpeptin attenuates calpain activation and cardiomyocyte loss in pressure-overloaded feline myocardium

(2008) Santhosh K. Mani et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Src kinases in systemic sclerosis: Central roles in fibroblast activation and in skin fibrosis

(2008) Catherine Skhirtladze et al.   ARTHRITIS AND RHEUMATISM

Mechanisms of Cardiac Dysfunction Associated With Tyrosine Kinase Inhibitor Cancer Therapeutics

(2008) Ming Hui Chen et al.   CIRCULATION

Dual inhibition of c-abl and PDGF receptor signaling by dasatinib and nilotinib for the treatment of dermal fibrosis

(2008) Alfiya Akhmetshina et al.   FASEB JOURNAL

Intracellular tyrosine kinases as novel targets for anti-fibrotic therapy in systemic sclerosis

(2008) J. H. W. Distler et al.   RHEUMATOLOGY

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL