Dasatinib prevent hepatic fibrosis induced by carbon tetrachloride (CCl4) via anti-inflammatory and antioxidant mechanism

The Role of NADPH Oxidases (NOXs) in Liver Fibrosis and the Activation of Myofibroblasts

(2016) Shuang Liang et al.   Frontiers in Physiology

Promising Therapy Candidates for Liver Fibrosis

(2016) Ping Wang et al.   Frontiers in Physiology

Dasatinib Reduces Lung Inflammation and Fibrosis in Acute Experimental Silicosis

(2016) Fernanda Ferreira Cruz et al.   PLoS One

Hepatoprotective Effect of Wheat-Based Solid-State Fermented Antrodia cinnamomea in Carbon Tetrachloride-Induced Liver Injury in Rat

(2016) Huan-Wen Chiu et al.   PLoS One

Mitochondrial Src tyrosine kinase plays a role in the cardioprotective effect of ischemic preconditioning by modulating complex I activity and mitochondrial ROS generation

(2015) H. Ge et al.   FREE RADICAL RESEARCH

Dasatinib attenuated bleomycin-induced pulmonary fibrosis in mice

(2015) Oznur Yilmaz et al.   GROWTH FACTORS

Protective effects of sesamin on liver fibrosis through antioxidative and anti-inflammatory activities in rats

(2015) Xiaowei Chen et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Evaluation of anti-asthmatic and antioxidant potential of Boerhavia procumbens in toluene diisocyanate (TDI) treated rats

(2015) Jasia Bokhari et al.   JOURNAL OF ETHNOPHARMACOLOGY

Interactions between Myc and Mediators of Inflammation in Chronic Liver Diseases

(2015) Ting Liu et al.   MEDIATORS OF INFLAMMATION

The Role of Dendritic Cells in Fibrosis Progression in Nonalcoholic Fatty Liver Disease

(2015) Paloma Almeda-Valdes et al.   Biomed Research International

Tracking anti-fibrotic pathways of nilotinib and imatinib in experimentally induced liver fibrosis: An insight

(2014) Gamal E Shiha et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Oxidative Stress-Induced Signaling Pathways Implicated in the Pathogenesis of Parkinson’s Disease

(2014) Georgia S. Gaki et al.   NEUROMOLECULAR MEDICINE

The Src and c-Kit kinase inhibitor dasatinib enhances p53-mediated targeting of human acute myeloid leukemia stem cells by chemotherapeutic agents

(2013) C. Dos Santos et al.   BLOOD

Hepatoprotection with a chloroform extract of Launaea procumbens against CCl4-induced injuries in rats

(2012) Rahmat A Khan et al.   BMC Complementary and Alternative Medicine

TGF-β signaling in tissue fibrosis: Redox controls, target genes and therapeutic opportunities

(2012) Rohan Samarakoon et al.   CELLULAR SIGNALLING

Association between nitric oxide and 8-hydroxydeoxyguanosine levels in semen of diabetic men

(2012) Iraj Amiri et al.   Systems Biology in Reproductive Medicine

Oxidative stress is involved in Dasatinib-induced apoptosis in rat primary hepatocytes

(2012) Tao Xue et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Pathogenesis of Liver Fibrosis

(2011) Virginia Hernandez-Gea et al.   Annual Review of Pathology-Mechanisms of Disease

Comparison of early treatment with low doses of nilotinib, imatinib and a clinically relevant dose of silymarin in thioacetamide-induced liver fibrosis

(2011) Mohamed E. Shaker et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Nilotinib counteracts thioacetamide-induced hepatic oxidative stress and attenuates liver fibrosis progression

(2011) Mohamed E. Shaker et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Carbon tetrachloride: A hepatotoxin causes oxidative stress in murine peritoneal macrophage and peripheral blood lymphocyte cells

(2011) Asis Bala et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Inhibition of PDGF, TGF-β, and Abl signaling and reduction of liver fibrosis by the small molecule Bcr-Abl tyrosine kinase antagonist Nilotinib

(2011) Yuqing Liu et al.   JOURNAL OF HEPATOLOGY

Dasatinib Inhibits the Development of Metastases in a Mouse Model of Pancreatic Ductal Adenocarcinoma

(2010) Jennifer P. Morton et al.   GASTROENTEROLOGY

Dasatinib inhibits the secretion of TNF-α following TLR stimulation in vitro and in vivo

(2009) Cara K. Fraser et al.   EXPERIMENTAL HEMATOLOGY

Smad-Independent Transforming Growth Factor-β Regulation of Early Growth Response-1 and Sustained Expression in Fibrosis

(2008) Swati Bhattacharyya et al.   AMERICAN JOURNAL OF PATHOLOGY

Src kinases in systemic sclerosis: Central roles in fibroblast activation and in skin fibrosis

(2008) Catherine Skhirtladze et al.   ARTHRITIS AND RHEUMATISM

Novel agents to override imatinib resistance mechanisms

(2008) Asumi Yokota et al.   DRUG DEVELOPMENT RESEARCH

Identification of the Human Enzymes Involved in the Oxidative Metabolism of Dasatinib: An Effective Approach for Determining Metabolite Formation Kinetics

(2008) L. Wang et al.   DRUG METABOLISM AND DISPOSITION

Dual inhibition of c-abl and PDGF receptor signaling by dasatinib and nilotinib for the treatment of dermal fibrosis

(2008) Alfiya Akhmetshina et al.   FASEB JOURNAL

Ameliorative action of cyanobacterial phycoerythrin on CCl4-induced toxicity in rats

(2008) Badrish Soni et al.   TOXICOLOGY

Novel redox-dependent regulation of NOX5 by the tyrosine kinase c-Abl

(2007) Amina El Jamali et al.   FREE RADICAL BIOLOGY AND MEDICINE