H5N1 Influenza A Virus PB1-F2 Relieves HAX-1-Mediated Restriction of Avian Virus Polymerase PA in Human Lung Cells

Rapid evolution of the PB1-F2 virulence protein expressed by human seasonal H3N2 influenza viruses reduces inflammatory responses to infection

(2017) Julie McAuley et al.   Virology Journal

The Influenza Virus Protein PB1-F2 Increases Viral Pathogenesis through Neutrophil Recruitment and NK Cells Inhibition

(2016) Aurore Vidy et al.   PLoS One

Identification of mammalian-adapting mutations in the polymerase complex of an avian H5N1 influenza virus

(2015) Andrew S. Taft et al.   Nature Communications

NLRX1 prevents mitochondrial induced apoptosis and enhances macrophage antiviral immunity by interacting with influenza virus PB1-F2 protein

(2014) J. Jaworska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adaptation of Avian Influenza A Virus Polymerase in Mammals To Overcome the Host Species Barrier

(2013) B. Manz et al.   JOURNAL OF VIROLOGY

The CRAPome: a contaminant repository for affinity purification–mass spectrometry data

(2013) Dattatreya Mellacheruvu et al.   NATURE METHODS

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Viral and Host Factors Required for Avian H5N1 Influenza A Virus Replication in Mammalian Cells

(2013) Hong Zhang et al.   Viruses-Basel

Cellular Protein HAX1 Interacts with the Influenza A Virus PA Polymerase Subunit and Impedes Its Nuclear Translocation

(2012) W.-B. Hsu et al.   JOURNAL OF VIROLOGY

Structure-guided evolution of cyan fluorescent proteins towards a quantum yield of 93%

(2012) Joachim Goedhart et al.   Nature Communications

Hax-1: a regulator of calcium signaling and apoptosis progression with multiple roles in human disease

(2011) Thomas Simmen   EXPERT OPINION ON THERAPEUTIC TARGETS

HAX-1: A family of apoptotic regulators in health and disease

(2011) Solomon V. Yap et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Behaviour of influenza A viruses differentially expressing segment 2 gene products in vitro and in vivo

(2011) S. Tauber et al.   JOURNAL OF GENERAL VIROLOGY

Reassortment and Mutation of the Avian Influenza Virus Polymerase PA Subunit Overcome Species Barriers

(2011) A. Mehle et al.   JOURNAL OF VIROLOGY

Immunopathogenic and Antibacterial Effects of H3N2 Influenza A Virus PB1-F2 Map to Amino Acid Residues 62, 75, 79, and 82

(2011) I. V. Alymova et al.   JOURNAL OF VIROLOGY

PA Residues in the 2009 H1N1 Pandemic Influenza Virus Enhance Avian Influenza Virus Polymerase Activity in Mammalian Cells

(2011) K. A. Bussey et al.   JOURNAL OF VIROLOGY

Differential Contribution of PB1-F2 to the Virulence of Highly Pathogenic H5N1 Influenza A Virus in Mammalian and Avian Species

(2011) Mirco Schmolke et al.   PLoS Pathogens

The Influenza Virus Protein PB1-F2 Inhibits the Induction of Type I Interferon at the Level of the MAVS Adaptor Protein

(2011) Zsuzsanna T. Varga et al.   PLoS Pathogens

Influenza A Virus Protein PB1-F2 Exacerbates IFN-  Expression of Human Respiratory Epithelial Cells

(2010) R. Le Goffic et al.   JOURNAL OF IMMUNOLOGY

PB1-F2 Expression by the 2009 Pandemic H1N1 Influenza Virus Has Minimal Impact on Virulence in Animal Models

(2010) R. Hai et al.   JOURNAL OF VIROLOGY

A Single N66S Mutation in the PB1-F2 Protein of Influenza A Virus Increases Virulence by Inhibiting the Early Interferon Response In Vivo

(2010) G. M. Conenello et al.   JOURNAL OF VIROLOGY

PB1-F2 Proteins from H5N1 and 20th Century Pandemic Influenza Viruses Cause Immunopathology

(2010) Julie L. McAuley et al.   PLoS Pathogens

The Effects of Influenza A Virus PB1-F2 Protein on Polymerase Activity Are Strain Specific and Do Not Impact Pathogenesis

(2009) J. L. McAuley et al.   JOURNAL OF VIROLOGY

Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic

(2009) Gavin J. D. Smith et al.   NATURE

The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit

(2009) Alexandre Dias et al.   NATURE

Adaptive strategies of the influenza virus polymerase for replication in humans

(2009) Andrew Mehle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The proapoptotic influenza A virus protein PB1-F2 regulates viral polymerase activity by interaction with the PB1 protein

(2008) Igor Mazur et al.   CELLULAR MICROBIOLOGY

Epidemiology of H5N1 avian influenza

(2008) Karen S. Yee et al.   COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES

Influenza A Virus Strains Differ in Sensitivity to the Antiviral Action of Mx-GTPase

(2008) J. Dittmann et al.   JOURNAL OF VIROLOGY

Live Attenuated Influenza Viruses Containing NS1 Truncations as Vaccine Candidates against H5N1 Highly Pathogenic Avian Influenza

(2008) J. Steel et al.   JOURNAL OF VIROLOGY

The Anti-apoptotic Protein HAX-1 Interacts with SERCA2 and Regulates Its Protein Levels to Promote Cell Survival

(2008) Elizabeth Vafiadaki et al.   MOLECULAR BIOLOGY OF THE CELL