A Single N66S Mutation in the PB1-F2 Protein of Influenza A Virus Increases Virulence by Inhibiting the Early Interferon Response In Vivo

Influenza A Virus Polymerase Inhibits Type I Interferon Induction by Binding to Interferon β Promoter Stimulator 1

(2010) Atsushi Iwai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Influenza A Virus Protein PB1-F2 Exacerbates IFN-  Expression of Human Respiratory Epithelial Cells

(2010) R. Le Goffic et al.   JOURNAL OF IMMUNOLOGY

Lethal Dissemination of H5N1 Influenza Virus Is Associated with Dysregulation of Inflammation and Lipoxin Signaling in a Mouse Model of Infection

(2010) C. Cilloniz et al.   JOURNAL OF VIROLOGY

PB1-F2 Expression by the 2009 Pandemic H1N1 Influenza Virus Has Minimal Impact on Virulence in Animal Models

(2010) R. Hai et al.   JOURNAL OF VIROLOGY

Continued Evolution of H5N1 Influenza Viruses in Wild Birds, Domestic Poultry, and Humans in China from 2004 to 2009

(2010) Y. Li et al.   JOURNAL OF VIROLOGY

The PB2 Subunit of the Influenza Virus RNA Polymerase Affects Virulence by Interacting with the Mitochondrial Antiviral Signaling Protein and Inhibiting Expression of Beta Interferon

(2010) K. M. Graef et al.   JOURNAL OF VIROLOGY

PB1-F2 Proteins from H5N1 and 20th Century Pandemic Influenza Viruses Cause Immunopathology

(2010) Julie L. McAuley et al.   PLoS Pathogens

The Alpha/Beta Interferon Receptor Provides Protection against Influenza Virus Replication but Is Dispensable for Inflammatory Response Signaling

(2009) A. G. Goodman et al.   JOURNAL OF VIROLOGY

A Single-Amino-Acid Substitution in a Polymerase Protein of an H5N1 Influenza Virus Is Associated with Systemic Infection and Impaired T-Cell Activation in Mice

(2009) J. L. Fornek et al.   JOURNAL OF VIROLOGY

The Effects of Influenza A Virus PB1-F2 Protein on Polymerase Activity Are Strain Specific and Do Not Impact Pathogenesis

(2009) J. L. McAuley et al.   JOURNAL OF VIROLOGY

Early Control of H5N1 Influenza Virus Replication by the Type I Interferon Response in Mice

(2009) K. J. Szretter et al.   JOURNAL OF VIROLOGY

Early and sustained innate immune response defines pathology and death in nonhuman primates infected by highly pathogenic influenza virus

(2009) C. R. Baskin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Amino Acids in HA and PB2 Critical for the Transmission of H5N1 Avian Influenza Viruses in a Mammalian Host

(2009) Yuwei Gao et al.   PLoS Pathogens

Lethal Influenza Virus Infection in Macaques Is Associated with Early Dysregulation of Inflammatory Related Genes

(2009) Cristian Cillóniz et al.   PLoS Pathogens

The proapoptotic influenza A virus protein PB1-F2 regulates viral polymerase activity by interaction with the PB1 protein

(2008) Igor Mazur et al.   CELLULAR MICROBIOLOGY

NP, PB1, and PB2 Viral Genes Contribute to Altered Replication of H5N1 Avian Influenza Viruses in Chickens

(2008) J. L. Wasilenko et al.   JOURNAL OF VIROLOGY

Genetic Compatibility and Virulence of Reassortants Derived from Contemporary Avian H5N1 and Human H3N2 Influenza A Viruses

(2008) Li-Mei Chen et al.   PLoS Pathogens

H5N1 and 1918 Pandemic Influenza Virus Infection Results in Early and Excessive Infiltration of Macrophages and Neutrophils in the Lungs of Mice

(2008) Lucy A. Perrone et al.   PLoS Pathogens