Structural basis for proton conduction and inhibition by the influenza M2 protein
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Title
Structural basis for proton conduction and inhibition by the influenza M2 protein
Authors
Keywords
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Journal
PROTEIN SCIENCE
Volume 21, Issue 11, Pages 1620-1633
Publisher
Wiley
Online
2012-09-22
DOI
10.1002/pro.2158
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Note: Only part of the references are listed.- Membrane Protein Structure and Dynamics from NMR Spectroscopy
- (2012) Mei Hong et al. Annual Review of Physical Chemistry
- NMR Determination of Protein Partitioning into Membrane Domains with Different Curvatures and Application to the Influenza M2 Peptide
- (2012) Tuo Wang et al. BIOPHYSICAL JOURNAL
- Hydrogen-Bonding Partner of the Proton-Conducting Histidine in the Influenza M2 Proton Channel Revealed From 1H Chemical Shifts
- (2012) Mei Hong et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Paramagnetic Cu(II) for Probing Membrane Protein Structure and Function: Inhibition Mechanism of the Influenza M2 Proton Channel
- (2012) Yongchao Su et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Solid-State NMR Studies of Amyloid Fibril Structure
- (2011) Robert Tycko Annual Review of Physical Chemistry
- Evaluation of the antiviral drug susceptibility of influenza viruses in Italy from 2004/05 to 2009/10 epidemics and from the recent 2009 pandemic
- (2011) Simona Puzelli et al. ANTIVIRAL RESEARCH
- Structural and dynamic mechanisms for the function and inhibition of the M2 proton channel from influenza A virus
- (2011) Jun Wang et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Computational Studies of Influenza A Virus at Three Important Targets: Hemagglutinin, Neuraminidase and M2 Protein
- (2011) Thanyada Rungrotmongkol et al. CURRENT PHARMACEUTICAL DESIGN
- Emergence and Phylogenetic Analysis of Amantadine-Resistant Influenza A Subtype H3N2 Viruses in Dublin, Ireland, over Six Seasons from 2003/2004 to 2008/2009
- (2011) A. Salter et al. INTERVIROLOGY
- Adamantane- and Oseltamivir-Resistant Seasonal A (H1N1) and Pandemic A (H1N1) 2009 Influenza Viruses in Guangdong, China, during 2008 and 2009
- (2011) Jie Zhou et al. JOURNAL OF CLINICAL MICROBIOLOGY
- Free Energy Calculations on the Two Drug Binding Sites in the M2 Proton Channel
- (2011) Ruo-Xu Gu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Membrane-Dependent Effects of a Cytoplasmic Helix on the Structure and Drug Binding of the Influenza Virus M2 Protein
- (2011) Sarah Cady et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- NMR Detection of pH-Dependent Histidine–Water Proton Exchange Reveals the Conduction Mechanism of a Transmembrane Proton Channel
- (2011) Fanghao Hu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Specific Binding of Adamantane Drugs and Direction of Their Polar Amines in the Pore of the Influenza M2 Transmembrane Domain in Lipid Bilayers and Dodecylphosphocholine Micelles Determined by NMR Spectroscopy
- (2011) Sarah D. Cady et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Molecular Dynamics Simulation Directed Rational Design of Inhibitors Targeting Drug-Resistant Mutants of Influenza A Virus M2
- (2011) Jun Wang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Tidal surge in the M2 proton channel, sensed by 2D IR spectroscopy
- (2011) A. Ghosh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural Investigation of Rimantadine Inhibition of the AM2-BM2 Chimera Channel of Influenza Viruses
- (2011) Rafal M. Pielak et al. STRUCTURE
- Evolutionary genomics of the pandemic 2009 H1N1 influenza viruses (pH1N 1v)
- (2011) Yanhua Qu et al. Virology Journal
- Comprehensive assessment of 2009 pandemic influenza A (H1N1) virus drug susceptibility in vitro
- (2010) Larisa V Gubareva et al. ANTIVIRAL THERAPY
- Conformational plasticity of the influenza A M2 transmembrane helix in lipid bilayers under varying pH, drug binding, and membrane thickness
- (2010) Fanghao Hu et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Computational study of drug binding to the membrane-bound tetrameric M2 peptide bundle from influenza A virus
- (2010) Ekta Khurana et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Influenza Virus M2 Protein Mediates ESCRT-Independent Membrane Scission
- (2010) Jeremy S. Rossman et al. CELL
- Genetic Makeup of Amantadine-Resistant and Oseltamivir-Resistant Human Influenza A/H1N1 Viruses
- (2010) H. Zaraket et al. JOURNAL OF CLINICAL MICROBIOLOGY
- Multiple Proton Confinement in the M2 Channel from the Influenza A Virus
- (2010) Vincenzo Carnevale et al. Journal of Physical Chemistry C
- Conformational Changes of an Ion Channel Detected Through Water−Protein Interactions Using Solid-State NMR Spectroscopy
- (2010) Wenbin Luo et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Proton Transport through the Influenza A M2 Channel: Three-Dimensional Reference Interaction Site Model Study
- (2010) Saree Phongphanphanee et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Kinetic Analysis of the M2 Proton Conduction of the Influenza Virus
- (2010) Rafal M. Pielak et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers
- (2010) Sarah D. Cady et al. NATURE
- Structure and mechanism of proton transport through the transmembrane tetrameric M2 protein bundle of the influenza A virus
- (2010) R. Acharya et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Proton and cation transport activity of the M2 proton channel from influenza A virus
- (2010) T. Leiding et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Coexistence of two adamantane binding sites in the influenza A M2 ion channel
- (2010) M. R. Rosenberg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Insight into the Mechanism of the Influenza A Proton Channel from a Structure in a Lipid Bilayer
- (2010) M. Sharma et al. SCIENCE
- Mechanisms of Proton Conduction and Gating in Influenza M2 Proton Channels from Solid-State NMR
- (2010) F. Hu et al. SCIENCE
- Where does amantadine bind to the influenza virus M2 proton channel?
- (2010) Dima Kozakov et al. TRENDS IN BIOCHEMICAL SCIENCES
- Emergence of amantadine-resistant avian influenza H5N1 virus in India
- (2010) C. Tosh et al. VIRUS GENES
- Structure and Dynamics of Membrane Proteins by Magic Angle Spinning Solid-State NMR
- (2009) Ann McDermott Annual Review of Biophysics
- Structure and Function of the Influenza A M2 Proton Channel
- (2009) Sarah D. Cady et al. BIOCHEMISTRY
- Functional Studies and Modeling of Pore-Lining Residue Mutants of the Influenza A Virus M2 Ion Channel
- (2009) Victoria Balannik et al. BIOCHEMISTRY
- Binding Hot Spots and Amantadine Orientation in the Influenza A Virus M2 Proton Channel
- (2009) Gwo-Yu Chuang et al. BIOPHYSICAL JOURNAL
- Genomic events underlying the changes in adamantane resistance among influenza A(H3N2) viruses during 2006-2008
- (2009) Varough Deyde et al. Influenza and Other Respiratory Viruses
- Why Amantadine Loses Its Function in Influenza M2 Mutants: MD Simulations
- (2009) Chittima Laohpongspaisan et al. Journal of Chemical Information and Modeling
- High prevalence of amantadine resistance among circulating European porcine influenza A viruses
- (2009) A. Krumbholz et al. JOURNAL OF GENERAL VIROLOGY
- Accurate Measurement of Methyl13C Chemical Shifts by Solid-State NMR for the Determination of Protein Side Chain Conformation: The Influenza A M2 Transmembrane Peptide as an Example
- (2009) Mei Hong et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
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- (2009) Jun Wang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
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- (2009) E. Khurana et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2009) Y. Ohigashi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2009) C. Ma et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Free-energy profiles for ions in the influenza M2-TMD channel
- (2009) Morad Mustafa et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Reversion of Influenza A (H3N2) Virus from Amantadine Resistant to Amantadine Sensitive by Further Reassortment in Japan during the 2006-to-2007 Influenza Season
- (2008) Y. Furuse et al. JOURNAL OF CLINICAL MICROBIOLOGY
- Structure of Amantadine-Bound M2 Transmembrane Peptide of Influenza A in Lipid Bilayers from Magic-Angle-Spinning Solid-State NMR: The Role of Ser31 in Amantadine Binding
- (2008) Sarah D. Cady et al. JOURNAL OF MOLECULAR BIOLOGY
- Structure and mechanism of the M2 proton channel of influenza A virus
- (2008) Jason R. Schnell et al. NATURE
- Structural basis for the function and inhibition of an influenza virus proton channel
- (2008) Amanda L. Stouffer et al. NATURE
- Amantadine-induced conformational and dynamical changes of the influenza M2 transmembrane proton channel
- (2008) S. D. Cady et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Functional studies indicate amantadine binds to the pore of the influenza A virus M2 proton-selective ion channel
- (2008) X. Jing et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Interplay of Functional Tuning, Drug Resistance, and Thermodynamic Stability in the Evolution of the M2 Proton Channel from the Influenza A Virus
- (2008) Amanda L. Stouffer et al. STRUCTURE
- Initial structural and dynamic characterization of the M2 protein transmembrane and amphipathic helices in lipid bilayers
- (2003) Changlin Tian et al. PROTEIN SCIENCE
- Structure of the transmembrane region of the M2 protein H+ channel
- (2002) Junfeng Wang et al. PROTEIN SCIENCE
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