Philosophy of voltage-gated proton channels

Proton channel HVCN1 is required for effector functions of mouse eosinophils

(2013) Xiang Zhu et al.   BMC IMMUNOLOGY

Peregrination of the selectivity filter delineates the pore of the human voltage-gated proton channel hHV1

(2013) Deri Morgan et al.   JOURNAL OF GENERAL PHYSIOLOGY

Construction and validation of a homology model of the human voltage-gated proton channel hHV1

(2013) Kethika Kulleperuma et al.   JOURNAL OF GENERAL PHYSIOLOGY

Molecular mechanism of voltage sensing in voltage-gated proton channels

(2013) Carlos Gonzalez et al.   JOURNAL OF GENERAL PHYSIOLOGY

Voltage-Gated Proton Channels: Molecular Biology, Physiology, and Pathophysiology of the HV Family

(2013) Thomas E. DeCoursey   PHYSIOLOGICAL REVIEWS

Role of aspartate 132 at the orifice of a proton pathway in cytochrome c oxidase

(2013) A.-L. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transient protonation changes in channelrhodopsin-2 and their relevance to channel gating

(2013) V. A. Lorenz-Fonfria et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proton transfer through the water gossamer

(2013) Ali Hassanali et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis for the Counter-Transport Mechanism of a H+/Ca2+ Exchanger

(2013) T. Nishizawa et al.   SCIENCE

Ab initio calculations and validation of the pH-dependent structures of the His37-Trp41 quartet, the heart of acid activation and proton conductance in the M2 protein of Influenza A virus

(2013) Hao Dong et al.   Chemical Science

Lipopolysaccharide-sensitive H+ current in dendritic cells

(2012) Kalina Szteyn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

M2 Proton Channel Structural Validation from Full-Length Protein Samples in Synthetic Bilayers and E. coli Membranes

(2012) Yimin Miao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Water Networks in Fast Proton Transfer during Catalysis by Human Carbonic Anhydrase II

(2012) Rose Mikulski et al.   BIOCHEMISTRY

Water oxidation mechanism in photosystem II, including oxidations, proton release pathways, O―O bond formation and O2 release

(2012) Per E.M. Siegbahn   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Clinicopathological and Biological Significance of Human Voltage-gated Proton Channel Hv1 Protein Overexpression in Breast Cancer

(2012) Yifan Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NOX5 in Human Spermatozoa

(2012) Boris Musset et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Basis for allosteric open-state stabilization of voltage-gated potassium channels by intracellular cations

(2012) Samuel J. Goodchild et al.   JOURNAL OF GENERAL PHYSIOLOGY

Hydrogen-Bonding Partner of the Proton-Conducting Histidine in the Influenza M2 Proton Channel Revealed From 1H Chemical Shifts

(2012) Mei Hong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The voltage-gated proton channel Hv1 enhances brain damage from ischemic stroke

(2012) Long-Jun Wu et al.   NATURE NEUROSCIENCE

Zinc ions block H+/OH- channels in Chara australis

(2012) SABAH AL KHAZAALY et al.   PLANT CELL AND ENVIRONMENT

A Proton Leak Current through the Cardiac Sodium Channel Is Linked to Mixed Arrhythmia and the Dilated Cardiomyopathy Phenotype

(2012) Pascal Gosselin-Badaroudine et al.   PLoS One

Mechanism of proton/substrate coupling in the heptahelical lysosomal transporter cystinosin

(2012) R. Ruivo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for proton conduction and inhibition by the influenza M2 protein

(2012) Mei Hong et al.   PROTEIN SCIENCE

Proton channels in algae: reasons to be excited

(2012) Alison R. Taylor et al.   TRENDS IN PLANT SCIENCE

The cytoplasmic coiled-coil mediates cooperative gating temperature sensitivity in the voltage-gated H+ channel Hv1

(2012) Yuichiro Fujiwara et al.   Nature Communications

Intracellular Proton Access in a Cl−/H+ Antiporter

(2012) Hyun-Ho Lim et al.   PLOS BIOLOGY

Strong glucose dependence of electron current in human monocytes

(2011) Boris Musset et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Specific expression of the human voltage-gated proton channel Hv1 in highly metastatic breast cancer cells, promotes tumor progression and metastasis

(2011) Yifan Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Alternative Initial Proton Acceptors for the D Pathway ofRhodobacter sphaeroidesCytochromecOxidase

(2011) Lakshman Varanasi et al.   BIOCHEMISTRY

Subunit III-depleted cytochrome c oxidase provides insight into the process of proton uptake by proteins

(2011) Lakshman Varanasi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Water wires in atomistic models of the Hv1 proton channel

(2011) Mona L. Wood et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

A Theory for the Proton Transport of the Influenza Virus M2 Protein: Extensive Test against Conductance Data

(2011) Huan-Xiang Zhou   BIOPHYSICAL JOURNAL

Dynamic Mechanism of Proton Transfer in Mannitol 2-Dehydrogenase fromPseudomonas fluorescens

(2011) Mario Klimacek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanism of Proton Transfer in [FeFe]-Hydrogenase fromClostridium pasteurianum

(2011) Adam J. Cornish et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanistic Insight into the H2O/D2O Isotope Effect in the Proton Transport of the Influenza Virus M2 Protein

(2011) Huan-Xiang Zhou   JOURNAL OF MEMBRANE BIOLOGY

Protonation, Tautomerization, and Rotameric Structure of Histidine: A Comprehensive Study by Magic-Angle-Spinning Solid-State NMR

(2011) Shenhui Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NMR Detection of pH-Dependent Histidine–Water Proton Exchange Reveals the Conduction Mechanism of a Transmembrane Proton Channel

(2011) Fanghao Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aspartate 112 is the selectivity filter of the human voltage-gated proton channel

(2011) Boris Musset et al.   NATURE

Entrance of the proton pathway in cbb3-type heme-copper oxidases

(2011) H. J. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Voltage-gated proton channel in a dinoflagellate

(2011) S. M. E. Smith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proton transfer via a transient linear water-molecule chain in a membrane protein

(2011) E. Freier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Voltage-Gated H+ Channel Underlying pH Homeostasis in Calcifying Coccolithophores

(2011) Alison R. Taylor et al.   PLOS BIOLOGY

A pH-Dependent Conformational Ensemble Mediates Proton Transport through the Influenza A/M2 Protein

(2010) Alexei L. Polishchuk et al.   BIOCHEMISTRY

Decoupling Mutations in the D-Channel of theaa3-Type CytochromecOxidase fromRhodobacter sphaeroidesSuggest That a Continuous Hydrogen-Bonded Chain of Waters Is Essential for Proton Pumping

(2010) Jiapeng Zhu et al.   BIOCHEMISTRY

Structural and energetic basis for H+ versus Na+ binding selectivity in ATP synthase Fo rotors

(2010) Alexander Krah et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Functional reconstitution of influenza A M2(22–62)

(2010) Emily Peterson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Acid Extrusion from Human Spermatozoa Is Mediated by Flagellar Voltage-Gated Proton Channel

(2010) Polina V. Lishko et al.   CELL

The Role and Structure of the Carboxyl-terminal Domain of the Human Voltage-gated Proton Channel Hv1

(2010) Shu Jie Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chemical Reactivities of Cysteine Substitutions in Subunitaof ATP Synthase Define Residues Gating H+Transport from Each Side of the Membrane

(2010) Hui Dong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Function of the HVCN1 proton channel in airway epithelia and a naturally occurring mutation, M91T

(2010) David Iovannisci et al.   JOURNAL OF GENERAL PHYSIOLOGY

Simulating Proton Transport through a Simplified Model for Trans-Membrane Proteins

(2010) Lynsey M. S. Shepherd et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Zinc inhibition of monomeric and dimeric proton channels suggests cooperative gating

(2010) Boris Musset et al.   JOURNAL OF PHYSIOLOGY-LONDON

Kinetic Analysis of the M2 Proton Conduction of the Influenza Virus

(2010) Rafal M. Pielak et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

HVCN1 modulates BCR signal strength via regulation of BCR-dependent generation of reactive oxygen species

(2010) Melania Capasso et al.   NATURE IMMUNOLOGY

An aqueous H+ permeation pathway in the voltage-gated proton channel Hv1

(2010) I Scott Ramsey et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Voltage-Gated Proton Channels Find Their Dream Job Managing the Respiratory Burst in Phagocytes

(2010) Thomas E. DeCoursey   PHYSIOLOGY

Molecular and Functional Characterization of Hv1 Proton Channel in Human Granulocytes

(2010) Gábor L. Petheő et al.   PLoS One

Structure and mechanism of proton transport through the transmembrane tetrameric M2 protein bundle of the influenza A virus

(2010) R. Acharya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proton and cation transport activity of the M2 proton channel from influenza A virus

(2010) T. Leiding et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insight into the Mechanism of the Influenza A Proton Channel from a Structure in a Lipid Bilayer

(2010) M. Sharma et al.   SCIENCE

Mechanisms of Proton Conduction and Gating in Influenza M2 Proton Channels from Solid-State NMR

(2010) F. Hu et al.   SCIENCE

A New Type of Proton Coordination in an F1Fo-ATP Synthase Rotor Ring

(2010) Laura Preiss et al.   PLOS BIOLOGY

Role of the glutamate 185 residue in proton translocation mediated by the proton-coupled folate transporter SLC46A1

(2009) Ersin Selcuk Unal et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Essentials for ATP Synthesis by F1F0ATP Synthases

(2009) Christoph von Ballmoos et al.   Annual Review of Biochemistry

Voltage-gated proton channel is expressed on phagosomes

(2009) Yoshifumi Okochi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

High resolution crystal structure of Paracoccus denitrificans cytochrome c oxidase: New insights into the active site and the proton transfer pathways

(2009) Juergen Koepke et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Concerted action of two cation filters in the aquaporin water channel

(2009) Binghua Wu et al.   EMBO JOURNAL

Identification of Thr29as a Critical Phosphorylation Site That Activates the Human Proton ChannelHvcn1in Leukocytes

(2009) Boris Musset et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

VSOP/Hv1 proton channels sustain calcium entry, neutrophil migration, and superoxide production by limiting cell depolarization and acidification

(2009) Antoun El Chemaly et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Functional Hydration and Conformational Gating of Proton Uptake in Cytochrome c Oxidase

(2009) Rowan M. Henry et al.   JOURNAL OF MOLECULAR BIOLOGY

Strong cooperativity between subunits in voltage-gated proton channels

(2009) Carlos Gonzalez et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The opening of the two pores of the Hv1 voltage-gated proton channel is tuned by cooperativity

(2009) Francesco Tombola et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Hv1 proton channels are required for high-level NADPH oxidase-dependent superoxide production during the phagocyte respiratory burst

(2009) I. S. Ramsey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Voltage-gated proton channels maintain pH in human neutrophils during phagocytosis

(2009) D. Morgan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of the functional core of the influenza A virus A/M2 proton-selective ion channel

(2009) C. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alternative Sites for Proton Entry from the Cytoplasm to the Quinone Binding Site inEscherichia coliSuccinate Dehydrogenase†

(2008) Victor W. T. Cheng et al.   BIOCHEMISTRY

Special Pair Dance and Partner Selection: Elementary Steps in Proton Transport in Liquid Water

(2008) Omer Markovitch et al.   JOURNAL OF PHYSICAL CHEMISTRY B

The Voltage-Gated Proton Channel Hv1 Has Two Pores, Each Controlled by One Voltage Sensor

(2008) Francesco Tombola et al.   NEURON

A pH-stabilizing role of voltage-gated proton channels in IgE-mediated activation of human basophils

(2008) B. Musset et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multimeric nature of voltage-gated proton channels

(2008) Hans P. Koch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dimeric subunit stoichiometry of the human voltage-dependent proton channel Hv1

(2008) S.-Y. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proton Transport through Influenza A Virus M2 Protein Reconstituted in Vesicles

(2007) J. Craig Moffat et al.   BIOPHYSICAL JOURNAL