Nuclear receptor agonist-driven modification of inflammation and amyloid pathology enhances and sustains cognitive improvements in a mouse model of Alzheimer’s disease

Neuronally-directed effects of RXR activation in a mouse model of Alzheimer’s disease

(2017) M. M. Mariani et al.   Scientific Reports

Microglial brain region−dependent diversity and selective regional sensitivities to aging

(2016) Kathleen Grabert et al.   NATURE NEUROSCIENCE

Double-blind, placebo-controlled, proof-of-concept trial of bexarotene in moderate Alzheimer’s disease

(2016) Jeffrey L. Cummings et al.   Alzheimers Research & Therapy

Combined Liver X Receptor/Peroxisome Proliferator-activated Receptor γ Agonist Treatment Reduces Amyloid β Levels and Improves Behavior in Amyloid Precursor Protein/Presenilin 1 Mice

(2015) Rebecca Skerrett et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ABCA1 is Necessary for Bexarotene-Mediated Clearance of Soluble Amyloid Beta from the Hippocampus of APP/PS1 Mice

(2015) Angela W. Corona et al.   Journal of Neuroimmune Pharmacology

Activation of the nuclear receptor PPARδ is neuroprotective in a transgenic mouse model of Alzheimer’s disease through inhibition of inflammation

(2015) Tarja Malm et al.   Journal of Neuroinflammation

Omega-3 Fatty Acids Augment the Actions of Nuclear Receptor Agonists in a Mouse Model of Alzheimer's Disease

(2015) B. T. Casali et al.   JOURNAL OF NEUROSCIENCE

Nuclear Receptors License Phagocytosis by Trem2+ Myeloid Cells in Mouse Models of Alzheimer's Disease

(2015) J. C. Savage et al.   JOURNAL OF NEUROSCIENCE

Amyloid-β Pathology andAPOEGenotype Modulate Retinoid X Receptor Agonist Activityin Vivo

(2014) Leon M. Tai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HDL and cognition in neurodegenerative disorders

(2014) David A. Hottman et al.   NEUROBIOLOGY OF DISEASE

ATP-binding cassette transporter A1: From metabolism to neurodegeneration

(2014) Radosveta Koldamova et al.   NEUROBIOLOGY OF DISEASE

Nuclear receptors in neurodegenerative diseases

(2014) Rebecca Skerrett et al.   NEUROBIOLOGY OF DISEASE

High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3

(2013) Dominic De Nardo et al.   NATURE IMMUNOLOGY

Response to Comments on "ApoE-Directed Therapeutics Rapidly Clear  -Amyloid and Reverse Deficits in AD Mouse Models"

(2013) G. E. Landreth et al.   SCIENCE

Comment on "ApoE-Directed Therapeutics Rapidly Clear  -Amyloid and Reverse Deficits in AD Mouse Models"

(2013) N. F. Fitz et al.   SCIENCE

Evidence for impaired amyloid β clearance in Alzheimer's disease

(2013) Kristin R Wildsmith et al.   Alzheimers Research & Therapy

Neurotoxicity of Amyloid  -Protein: Synaptic and Network Dysfunction

(2013) L. Mucke et al.   Cold Spring Harbor Perspectives in Medicine

Loss of Interleukin Receptor-Associated Kinase 4 Signaling Suppresses Amyloid Pathology and Alters Microglial Phenotype in a Mouse Model of Alzheimer's Disease

(2012) B. Cameron et al.   JOURNAL OF NEUROSCIENCE

Mechanisms Underlying the Rapid Peroxisome Proliferator-Activated Receptor- -Mediated Amyloid Clearance and Reversal of Cognitive Deficits in a Murine Model of Alzheimer's Disease

(2012) S. Mandrekar-Colucci et al.   JOURNAL OF NEUROSCIENCE

ApoE-Directed Therapeutics Rapidly Clear  -Amyloid and Reverse Deficits in AD Mouse Models

(2012) P. E. Cramer et al.   SCIENCE

ATP-binding Cassette Transporter A1 Mediates the Beneficial Effects of the Liver X Receptor Agonist GW3965 on Object Recognition Memory and Amyloid Burden in Amyloid Precursor Protein/Presenilin 1 Mice

(2010) James J. Donkin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Liver X Receptor Agonist Treatment Ameliorates Amyloid Pathology and Memory Deficits Caused by High-Fat Diet in APP23 Mice

(2010) N. F. Fitz et al.   JOURNAL OF NEUROSCIENCE

Object recognition memory and the rodent hippocampus

(2009) N. J. Broadbent et al.   LEARNING & MEMORY

Nuclear Receptors and Inflammatory Diseases

(2008) Kun Wang et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

OSBP Negatively Regulates ABCA1 Protein Stability

(2008) Kristin Bowden et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ApoE Promotes the Proteolytic Degradation of Aβ

(2008) Qingguang Jiang et al.   NEURON