Nuclear receptor agonist-driven modification of inflammation and amyloid pathology enhances and sustains cognitive improvements in a mouse model of Alzheimer’s disease
出版年份 2018 全文链接
标题
Nuclear receptor agonist-driven modification of inflammation and amyloid pathology enhances and sustains cognitive improvements in a mouse model of Alzheimer’s disease
作者
关键词
Nuclear receptors, RXR, Microgliosis, ABCA1, APOE, Bexarotene, AD
出版物
Journal of Neuroinflammation
Volume 15, Issue 1, Pages -
出版商
Springer Nature
发表日期
2018-02-15
DOI
10.1186/s12974-018-1091-y
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Neuronally-directed effects of RXR activation in a mouse model of Alzheimer’s disease
- (2017) M. M. Mariani et al. Scientific Reports
- Microglial brain region−dependent diversity and selective regional sensitivities to aging
- (2016) Kathleen Grabert et al. NATURE NEUROSCIENCE
- Double-blind, placebo-controlled, proof-of-concept trial of bexarotene in moderate Alzheimer’s disease
- (2016) Jeffrey L. Cummings et al. Alzheimers Research & Therapy
- Combined Liver X Receptor/Peroxisome Proliferator-activated Receptor γ Agonist Treatment Reduces Amyloid β Levels and Improves Behavior in Amyloid Precursor Protein/Presenilin 1 Mice
- (2015) Rebecca Skerrett et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ABCA1 is Necessary for Bexarotene-Mediated Clearance of Soluble Amyloid Beta from the Hippocampus of APP/PS1 Mice
- (2015) Angela W. Corona et al. Journal of Neuroimmune Pharmacology
- Activation of the nuclear receptor PPARδ is neuroprotective in a transgenic mouse model of Alzheimer’s disease through inhibition of inflammation
- (2015) Tarja Malm et al. Journal of Neuroinflammation
- Omega-3 Fatty Acids Augment the Actions of Nuclear Receptor Agonists in a Mouse Model of Alzheimer's Disease
- (2015) B. T. Casali et al. JOURNAL OF NEUROSCIENCE
- Nuclear Receptors License Phagocytosis by Trem2+ Myeloid Cells in Mouse Models of Alzheimer's Disease
- (2015) J. C. Savage et al. JOURNAL OF NEUROSCIENCE
- Amyloid-β Pathology andAPOEGenotype Modulate Retinoid X Receptor Agonist Activityin Vivo
- (2014) Leon M. Tai et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- HDL and cognition in neurodegenerative disorders
- (2014) David A. Hottman et al. NEUROBIOLOGY OF DISEASE
- ATP-binding cassette transporter A1: From metabolism to neurodegeneration
- (2014) Radosveta Koldamova et al. NEUROBIOLOGY OF DISEASE
- Nuclear receptors in neurodegenerative diseases
- (2014) Rebecca Skerrett et al. NEUROBIOLOGY OF DISEASE
- High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3
- (2013) Dominic De Nardo et al. NATURE IMMUNOLOGY
- Response to Comments on "ApoE-Directed Therapeutics Rapidly Clear -Amyloid and Reverse Deficits in AD Mouse Models"
- (2013) G. E. Landreth et al. SCIENCE
- Comment on "ApoE-Directed Therapeutics Rapidly Clear -Amyloid and Reverse Deficits in AD Mouse Models"
- (2013) N. F. Fitz et al. SCIENCE
- Evidence for impaired amyloid β clearance in Alzheimer's disease
- (2013) Kristin R Wildsmith et al. Alzheimers Research & Therapy
- Neurotoxicity of Amyloid -Protein: Synaptic and Network Dysfunction
- (2013) L. Mucke et al. Cold Spring Harbor Perspectives in Medicine
- Loss of Interleukin Receptor-Associated Kinase 4 Signaling Suppresses Amyloid Pathology and Alters Microglial Phenotype in a Mouse Model of Alzheimer's Disease
- (2012) B. Cameron et al. JOURNAL OF NEUROSCIENCE
- Mechanisms Underlying the Rapid Peroxisome Proliferator-Activated Receptor- -Mediated Amyloid Clearance and Reversal of Cognitive Deficits in a Murine Model of Alzheimer's Disease
- (2012) S. Mandrekar-Colucci et al. JOURNAL OF NEUROSCIENCE
- ApoE-Directed Therapeutics Rapidly Clear -Amyloid and Reverse Deficits in AD Mouse Models
- (2012) P. E. Cramer et al. SCIENCE
- ATP-binding Cassette Transporter A1 Mediates the Beneficial Effects of the Liver X Receptor Agonist GW3965 on Object Recognition Memory and Amyloid Burden in Amyloid Precursor Protein/Presenilin 1 Mice
- (2010) James J. Donkin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Liver X Receptor Agonist Treatment Ameliorates Amyloid Pathology and Memory Deficits Caused by High-Fat Diet in APP23 Mice
- (2010) N. F. Fitz et al. JOURNAL OF NEUROSCIENCE
- Object recognition memory and the rodent hippocampus
- (2009) N. J. Broadbent et al. LEARNING & MEMORY
- Nuclear Receptors and Inflammatory Diseases
- (2008) Kun Wang et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- OSBP Negatively Regulates ABCA1 Protein Stability
- (2008) Kristin Bowden et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ApoE Promotes the Proteolytic Degradation of Aβ
- (2008) Qingguang Jiang et al. NEURON
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