Down-regulation of Long Noncoding RNA MALAT1 Protects Hippocampal Neurons Against Excessive Autophagy and Apoptosis via the PI3K/Akt Signaling Pathway in Rats with Epilepsy

MALAT1/miR-127-5p Regulates Osteopontin (OPN)-Mediated Proliferation of Human Chondrocytes Through PI3K/Akt Pathway

(2017) Jun Liang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Long non-coding RNA MALAT1 promotes proliferation and suppresses apoptosis of glioma cells through derepressing Rap1B by sponging miR-101

(2017) Zhenjiang Li et al.   JOURNAL OF NEURO-ONCOLOGY

Long noncoding RNA Malat1 is a potent autophagy inducer protecting brain microvascular endothelial cells against oxygen-glucose deprivation/reoxygenation-induced injury by sponging miR-26b and upregulating ULK2 expression

(2017) Zhijun Li et al.   NEUROSCIENCE

Long non-coding RNA MALAT1 contributes to cell apoptosis by sponging miR-124 in Parkinson disease

(2017) Wei Liu et al.   Cell and Bioscience

Honokiol induces autophagy of neuroblastoma cells through activating the PI3K/Akt/mTOR and endoplasmic reticular stress/ERK1/2 signaling pathways and suppressing cell migration

(2016) Poh-Shiow Yeh et al.   CANCER LETTERS

Long non-coding RNA MALAT1 regulates retinal neurodegeneration through CREB signaling

(2016) J. Yao et al.   EMBO Molecular Medicine

Brivaracetam: Rationale for discovery and preclinical profile of a selective SV2A ligand for epilepsy treatment

(2016) Henrik Klitgaard et al.   EPILEPSIA

Tetrahydrocurcumin provides neuroprotection in rats after traumatic brain injury: autophagy and the PI3K/AKT pathways as a potential mechanism

(2016) Yongyue Gao et al.   JOURNAL OF SURGICAL RESEARCH

The Role of Long Noncoding RNAs in Neurodegenerative Diseases

(2016) Peixing Wan et al.   MOLECULAR NEUROBIOLOGY

Altered Long Noncoding RNA Expression Precedes the Course of Parkinson’s Disease—a Preliminary Report

(2016) Theo F. J. Kraus et al.   MOLECULAR NEUROBIOLOGY

The Neuroprotective Effects of Justicidin A on Amyloid Beta25–35-Induced Neuronal Cell Death Through Inhibition of Tau Hyperphosphorylation and Induction of Autophagy in SH-SY5Y Cells

(2016) Ming-Yao Gu et al.   NEUROCHEMICAL RESEARCH

Quercetin attenuates neuronal autophagy and apoptosis in rat traumatic brain injury model via activation of PI3K/Akt signaling pathway

(2016) Guoliang Du et al.   NEUROLOGICAL RESEARCH

Effect of lamotrigine on epilepsy-induced cognitive impairment and hippocampal neuronal apoptosis in pentylenetetrazole-kindled animal model

(2016) Bing Zhang et al.   SYNAPSE

Long noncoding RNAs and Alzheimer's disease

(2016) Qiong Luo et al.   Clinical Interventions in Aging

Infections, inflammation and epilepsy

(2015) Annamaria Vezzani et al.   ACTA NEUROPATHOLOGICA

Long Noncoding RNA MALAT1 Promotes Aggressive Renal Cell Carcinoma through Ezh2 and Interacts with miR-205

(2015) H. Hirata et al.   CANCER RESEARCH

Interleukin-1β plays a role in the pathogenesis of mesial temporal lobe epilepsy through the PI3K/Akt/mTOR signaling pathway in hippocampal neurons

(2015) Zhaohua Xiao et al.   JOURNAL OF NEUROIMMUNOLOGY

Epilepsy: new advances

(2015) Solomon L Moshé et al.   LANCET

Autophagy Supports Breast Cancer Stem Cell Maintenance by Regulating IL6 Secretion

(2015) Paola Maycotte et al.   MOLECULAR CANCER RESEARCH

Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine?

(2015) Shikha Satendra Singh   WORLD JOURNAL OF GASTROENTEROLOGY

LncRNA MALAT1 enhances oncogenic activities of EZH2 in castration-resistant prostate cancer

(2015) Dejie Wang et al.   Oncotarget

ILAE Official Report: A practical clinical definition of epilepsy

(2014) Robert S. Fisher et al.   EPILEPSIA

Long noncoding RNA MALAT1 promotes brain metastasis by inducing epithelial-mesenchymal transition in lung cancer

(2014) Liqin Shen et al.   JOURNAL OF NEURO-ONCOLOGY

Inhibition of cathepsin S induces autophagy and apoptosis in human glioblastoma cell lines through ROS-mediated PI3K/AKT/mTOR/p70S6K and JNK signaling pathways

(2014) Li Zhang et al.   TOXICOLOGY LETTERS

MALAT1 promotes the proliferation and metastasis of osteosarcoma cells by activating the PI3K/Akt pathway

(2014) Yongqiang Dong et al.   TUMOR BIOLOGY

MicroRNA-101 suppresses motility of bladder cancer cells by targeting c-Met

(2013) Zhenghui Hu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Roles of long noncoding RNAs in brain development, functional diversification and neurodegenerative diseases

(2013) Ping Wu et al.   BRAIN RESEARCH BULLETIN

MALAT-1, a non protein-coding RNA is upregulated in the cerebellum, hippocampus and brain stem of human alcoholics

(2012) Rosemarie Kryger et al.   ALCOHOL

The Noncoding RNA MALAT1 Is a Critical Regulator of the Metastasis Phenotype of Lung Cancer Cells

(2012) T. Gutschner et al.   CANCER RESEARCH

Excessive Autophagy Contributes to Neuron Death in Cerebral Ischemia

(2012) Ruoyang Shi et al.   CNS Neuroscience & Therapeutics

The hallmarks of cancer

(2012) Tony Gutschner et al.   RNA Biology

Diazoxide preconditioning against seizure-induced oxidative injury is via the PI3K/Akt pathway in epileptic rat

(2011) Yuan Xue et al.   NEUROSCIENCE LETTERS

A long nuclear-retained non-coding RNA regulates synaptogenesis by modulating gene expression

(2010) Delphine Bernard et al.   EMBO JOURNAL

Estimation of the burden of active and life-time epilepsy: A meta-analytic approach

(2010) Anthony K. Ngugi et al.   EPILEPSIA

MicroRNA-101 Regulates Amyloid Precursor Protein Expression in Hippocampal Neurons

(2010) Elisa Vilardo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY