Thetrans-sialidase, the majorTrypanosoma cruzivirulence factor: Three decades of studies

Trypanosoma cruzitrans-Sialidase Prevents Elicitation of Th1 Cell Response via Interleukin 10 and Downregulates Th1 Effector Cells

(2015) Pablo Ruiz Díaz et al.   INFECTION AND IMMUNITY

Glycans in immune recognition and response

(2014) Ron Amon et al.   CARBOHYDRATE RESEARCH

Siglec-G/10 in self-nonself discrimination of innate and adaptive immunity

(2014) G.-Y. Chen et al.   GLYCOBIOLOGY

The interplay between Siglecs and sialylated pathogens

(2014) Y.-C. Chang et al.   GLYCOBIOLOGY

α2-3 Sialic acid glycoconjugate loss and its effect on infection with Toxoplasma parasites

(2013) Yoshifumi Nishikawa et al.   EXPERIMENTAL PARASITOLOGY

Addition of α-O-GlcNAc to threonine residues define the post-translational modification of mucin-like molecules in Trypanosoma cruzi

(2013) Lucia Mendonça-Previato et al.   GLYCOCONJUGATE JOURNAL

Trypanosoma cruzi trans-sialidase initiates a program independent of the transcription factors RORγt and Ahr that leads to IL-17 production by activated B cells

(2013) Daniela A Bermejo et al.   NATURE IMMUNOLOGY

Differential Distribution of Genes Encoding the Virulence Factor Trans-Sialidase along Trypanosoma cruzi Discrete Typing Units

(2013) Juan M. Burgos et al.   PLoS One

Trypanosoma cruzi Coaxes Cardiac Fibroblasts into Preventing Cardiomyocyte Death by Activating Nerve Growth Factor Receptor TrkA

(2013) Daniel Aridgides et al.   PLoS One

Galectin-3 Silencing Inhibits Epirubicin-Induced ATP Binding Cassette Transporters and Activates the Mitochondrial Apoptosis Pathway via β-Catenin/GSK-3β Modulation in Colorectal Carcinoma

(2013) Yung-Kuo Lee et al.   PLoS One

Trans-sialidase StimulatesEat MeResponse from Epithelial Cells

(2013) Claire E. Butler et al.   TRAFFIC

Trypanosoma cruzi: Entry into Mammalian Host Cells and Parasitophorous Vacuole Formation

(2013) Emile Santos Barrias et al.   Frontiers in Immunology

Active penetration of Trypanosoma cruzi into host cells: historical considerations and current concepts

(2013) Wanderley de Souza et al.   Frontiers in Immunology

Thymic atrophy in acute experimental Chagas disease is associated with an imbalance of stress hormones

(2012) Ailin Lepletier et al.   Annals of the New York Academy of Sciences

Multifarious roles of sialic acids in immunity

(2012) Ajit Varki et al.   Annals of the New York Academy of Sciences

Trypanosoma cruzi trans-sialidase as a multifunctional enzyme in Chagas’ disease

(2012) Sergio S. C. dC-Rubin et al.   CELLULAR MICROBIOLOGY

Trypanosoma cruzi trans-Sialidase in Complex with a Neutralizing Antibody: Structure/Function Studies towards the Rational Design of Inhibitors

(2012) Alejandro Buschiazzo et al.   PLoS Pathogens

Evasion of immune responses by Trypanosoma cruzi, the etiological agent of Chagas disease

(2011) G.A. DosReis   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Viruses and sialic acids: rules of engagement

(2011) Ursula Neu et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Invasion of Trypanosoma cruzi into host cells is impaired by N-propionylmannosamine and other N-acylmannosamines

(2011) Thorsten Lieke et al.   GLYCOCONJUGATE JOURNAL

Effects of Plasmodium berghei on thymus: High levels of apoptosis and premature egress of CD4+CD8+ thymocytes in experimentally infected mice

(2011) Carolina Francelin et al.   IMMUNOBIOLOGY

A new class of mechanism-based inhibitors for Trypanosoma cruzi trans-sialidase and their influence on parasite virulence

(2010) S. T. Carvalho et al.   GLYCOBIOLOGY

Identification of glycoproteins targeted by Trypanosoma cruzi trans-sialidase, a virulence factor that disturbs lymphocyte glycosylation

(2010) R. P. Muia et al.   GLYCOBIOLOGY

Trypanosoma cruziSubverts Host Cell Sialylation and May Compromise Antigen-specific CD8+T Cell Responses

(2010) Leonardo Freire-de-Lima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sialidase‐Based Anti–Influenza Virus Therapy Protects against Secondary Pneumococcal Infection

(2010) Maria Hedlund et al.   JOURNAL OF INFECTIOUS DISEASES

The Sialome—Far More Than the Sum of Its Parts

(2010) Miriam Cohen et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Role of the JNK/c-Jun/AP-1 signaling pathway in galectin-1-induced T-cell death

(2010) B Brandt et al.   Cell Death & Disease

Advances in the Biology and Chemistry of Sialic Acids

(2009) Xi Chen et al.   ACS Chemical Biology

Effect of sialic acid loss on dendritic cell maturation

(2009) Hélio J. Crespo et al.   IMMUNOLOGY

Apoptosis in Toxoplasma gondii activated T cells: The role of IFNγ in enhanced alteration of Bcl-2 expression and mitochondrial membrane potential

(2009) Sakhina Begum-Haque et al.   MICROBIAL PATHOGENESIS

A New Generation of SpecificTrypanosoma cruzi trans-Sialidase Inhibitors

(2008) Sabrina Buchini et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION