Galectin-3 Silencing Inhibits Epirubicin-Induced ATP Binding Cassette Transporters and Activates the Mitochondrial Apoptosis Pathway via β-Catenin/GSK-3β Modulation in Colorectal Carcinoma

Pituitary homeobox 2 (PITX2) protects renal cancer cell lines against doxorubicin toxicity by transcriptional activation of the multidrug transporter ABCB1

(2013) Wing-Kee Lee et al.   INTERNATIONAL JOURNAL OF CANCER

A Potential Daidzein Derivative Enhances Cytotoxicity of Epirubicin on Human Colon Adenocarcinoma Caco-2 Cells

(2012) Yu-Li Lo   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

7,3′,4′-Trihydroxyisoflavone modulates multidrug resistance transporters and induces apoptosis via production of reactive oxygen species

(2012) Yu-Li Lo et al.   TOXICOLOGY

Increased galectin-3 facilitates leukemia cell survival from apoptotic stimuli

(2011) Yi-Lin Cheng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Glucosylceramide synthase inhibitor PDMP sensitizes chronic myeloid leukemia T315I mutant to Bcr-Abl inhibitor and cooperatively induces glycogen synthase kinase-3-regulated apoptosis

(2011) Wei-Ching Huang et al.   FASEB JOURNAL

Transient gene silencing of galectin-3 suppresses pancreatic cancer cell migration and invasion through degradation of β-catenin

(2011) Tsutomu Kobayashi et al.   INTERNATIONAL JOURNAL OF CANCER

Galectin-3 (Gal-3) induced by leukemia microenvironment promotes drug resistance and bone marrow lodgment in chronic myelogenous leukemia

(2011) M. Yamamoto-Sugitani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Serum levels of galectin-3 and its ligand 90k/mac-2bp in colorectal cancer patients

(2010) Palma A. Iacovazzi et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Expression of phosphorylated Stat5 predicts expression of cyclin D1 and correlates with poor prognosis of colonic adenocarcinoma

(2010) Yinling Mao et al.   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

Multifunctional Nanoparticles Delivering Small Interfering RNA and Doxorubicin Overcome Drug Resistance in Cancer

(2010) Yunching Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRAIL sensitize MDR cells to MDR-related drugs by down-regulation of P-glycoprotein through inhibition of DNA-PKcs/Akt/GSK-3β pathway and activation of caspases

(2010) Suk-Bin Seo et al.   Molecular Cancer

Glucosylceramide synthase upregulates MDR1 expression in the regulation of cancer drug resistance through cSrc and β-catenin signaling

(2010) Yong-Yu Liu et al.   Molecular Cancer

Reversal of ABC Drug Transporter-Mediated Multidrug Resistance in Cancer Cells: Evaluation of Current Strategies

(2010) Chung-Pu Wu et al.   Current Molecular Pharmacology

Galectin-3 regulates apoptosis and doxorubicin chemoresistance in papillary thyroid cancer cells

(2009) Chi-Iou Lin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Galectin-3 Mediates Nuclear β-Catenin Accumulation and Wnt Signaling in Human Colon Cancer Cells by Regulation of Glycogen Synthase Kinase-3β Activity

(2009) Shumei Song et al.   CANCER RESEARCH

Silencing of galectin-3 changes the gene expression and augments the sensitivity of gastric cancer cells to chemotherapeutic agents

(2009) Teak-Chin Cheong et al.   CANCER SCIENCE

Dietary Soy and Isoflavone Intake and Risk of Colorectal Cancer in the Japan Public Health Center-Based Prospective Study

(2008) M. Akhter et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Inhibit multidrug resistance and induce apoptosis by using glycocholic acid and epirubicin

(2008) Y.L. Lo et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Galectin-3 Protects Keratinocytes from UVB-Induced Apoptosis by Enhancing AKT Activation and Suppressing ERK Activation

(2008) Jun Saegusa et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

GSK-3β regulates cyclin D1 expression: A new target for chemotherapy

(2007) Fumi Takahashi-Yanaga et al.   CELLULAR SIGNALLING