miRNA regulation of innate immunity

Emerging role of non-coding RNA in oral cancer

(2018) Fatemeh Momen-Heravi et al.   CELLULAR SIGNALLING

Circulating and Exosome-Packaged Hepatitis C Single-Stranded RNA Induce Monocyte Differentiation via TLR7/8 to Polarized Macrophages and Fibrocytes

(2017) Banishree Saha et al.   JOURNAL OF IMMUNOLOGY

Alcohol-induced miR-155 and HDAC11 inhibit negative regulators of the TLR4 pathway and lead to increased LPS responsiveness of Kupffer cells in alcoholic liver disease

(2017) Shashi Bala et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Role of miRNAs in development and disease: Lessons learnt from small organisms

(2017) Swati Chandra et al.   LIFE SCIENCES

The PI3K/AKT signaling pathway: Associations of miRNAs with dysregulated gene expression in colorectal cancer

(2017) Martha L. Slattery et al.   MOLECULAR CARCINOGENESIS

MicroRNA therapeutics: towards a new era for the management of cancer and other diseases

(2017) Rajesha Rupaimoole et al.   NATURE REVIEWS DRUG DISCOVERY

Dicer-independent processing of small RNA duplexes: mechanistic insights and applications

(2017) Elena Herrera-Carrillo et al.   NUCLEIC ACIDS RESEARCH

miR-146a–Traf6regulatory axis controls autoimmunity and myelopoiesis, but is dispensable for hematopoietic stem cell homeostasis and tumor suppression

(2017) Nathaniel Magilnick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An NF-κB-microRNA regulatory network tunes macrophage inflammatory responses

(2017) Mati Mann et al.   Nature Communications

Regulation of microRNAs function by circular RNAs in human cancer

(2017) Chao Han et al.   Oncotarget

MicroRNA-21 Limits Uptake of Listeria monocytogenes by Macrophages to Reduce the Intracellular Niche and Control Infection

(2017) Daniel G. W. Johnston et al.   Frontiers in Cellular and Infection Microbiology

MicroRNA: Dynamic Regulators of Macrophage Polarization and Plasticity

(2017) Jezrom Bokcaerin Self-Fordham et al.   Frontiers in Immunology

The pro-inflammatory effects of miR-155 promote liver fibrosis and alcohol-induced steatohepatitis

(2016) Shashi Bala et al.   JOURNAL OF HEPATOLOGY

TLR4, TLR7/8 agonist-induced miR-146a promotes macrophage tolerance to MyD88-dependent TLR agonists

(2016) M. Abu Nahid et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Control of the Inflammatory Macrophage Transcriptional Signature by miR-155

(2016) Kyle A. Jablonski et al.   PLoS One

MicroRNA-21 promotes cell proliferation, migration, and resistance to apoptosis through PTEN/PI3K/AKT signaling pathway in esophageal cancer

(2016) Yan-Ran Wu et al.   TUMOR BIOLOGY

miR-181a Induces Macrophage Polarized to M2 Phenotype and Promotes M2 Macrophage-mediated Tumor Cell Metastasis by Targeting KLF6 and C/EBPα

(2016) Jia Bi et al.   Molecular Therapy-Nucleic Acids

Colony stimulating factor-1 receptor signaling networks inhibit mouse macrophage inflammatory responses by induction of microRNA-21

(2015) C. I. Caescu et al.   BLOOD

Poly(I:C) induced microRNA-146a regulates epithelial barrier and secretion of proinflammatory cytokines in human nasal epithelial cells

(2015) Ryo Miyata et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

MicroRNA Cargo of Extracellular Vesicles from Alcohol-exposed Monocytes Signals Naive Monocytes to Differentiate into M2 Macrophages

(2015) Banishree Saha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased number of circulating exosomes and their microRNA cargos are potential novel biomarkers in alcoholic hepatitis

(2015) Fatemeh Momen-Heravi et al.   Journal of Translational Medicine

The biological functions of miRNAs: lessons from in vivo studies

(2015) Joana A. Vidigal et al.   TRENDS IN CELL BIOLOGY

Exosomes derived from alcohol-treated hepatocytes horizontally transfer liver specific miRNA-122 and sensitize monocytes to LPS

(2015) Fatemeh Momen-Heravi et al.   Scientific Reports

MicroRNA as Type I Interferon-Regulated Transcripts and Modulators of the Innate Immune Response

(2015) Samuel C. Forster et al.   Frontiers in Immunology

Turning 21: Induction of miR-21 as a Key Switch in the Inflammatory Response

(2015) Frederick J. Sheedy   Frontiers in Immunology

MicroRNA 21 Is a Homeostatic Regulator of Macrophage Polarization and Prevents Prostaglandin E2-Mediated M2 Generation

(2015) Zhuo Wang et al.   PLoS One

MicroRNA-155 Deficiency Attenuates Liver Steatosis and Fibrosis without Reducing Inflammation in a Mouse Model of Steatohepatitis

(2015) Timea Csak et al.   PLoS One

MicroRNA-375 inhibits colorectal cancer growth by targeting PIK3CA

(2014) Yihui Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Emerging technologies in extracellular vesicle-based molecular diagnostics

(2014) Shidong Jia et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Engulfment of Apoptotic Cells by Macrophages: A Role of MicroRNA-21 in the Resolution of Wound Inflammation

(2014) A. Das et al.   JOURNAL OF IMMUNOLOGY

Downregulation of MicroRNA miR-526a by Enterovirus Inhibits RIG-I-Dependent Innate Immune Response

(2014) C. Xu et al.   JOURNAL OF VIROLOGY

Exosome-mediated delivery of functionally active miRNA-155 inhibitor to macrophages

(2014) Fatemeh Momen-Heravi et al.   Nanomedicine-Nanotechnology Biology and Medicine

Regulation of microRNA biogenesis

(2014) Minju Ha et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MicroRNA-29b Modulates Innate and Antigen-Specific Immune Responses in Mouse Models of Autoimmunity

(2014) Apolline Salama et al.   PLoS One

MicroRNA-26a negatively regulates toll-like receptor 3 expression of rat macrophages and ameliorates pristane induced arthritis in rats

(2014) Congshan Jiang et al.   ARTHRITIS RESEARCH & THERAPY

MicroRNAs, Major Players in B Cells Homeostasis and Function

(2014) Richard Danger et al.   Frontiers in Immunology

MicroRNA-146a: A Dominant, Negative Regulator of the Innate Immune Response

(2014) Reuben Saba et al.   Frontiers in Immunology

Identification of a microRNA landscape targeting the PI3K/Akt signaling pathway in inflammation-induced colorectal carcinogenesis

(2013) Claire Josse et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Current methods for the isolation of extracellular vesicles

(2013) Fatemeh Momen-Heravi et al.   BIOLOGICAL CHEMISTRY

miR-155: an ancient regulator of the immune system

(2013) Elena Vigorito et al.   IMMUNOLOGICAL REVIEWS

MicroRNA regulation of T-cell differentiation and function

(2013) Lukas T. Jeker et al.   IMMUNOLOGICAL REVIEWS

Overexpression of microRNA-21 is associated with elevated pro-inflammatory cytokines in dominant-negative TGF-β receptor type II mouse

(2013) Yugo Ando et al.   JOURNAL OF AUTOIMMUNITY

Neutral Sphingomyelinase 2 (nSMase2)-dependent Exosomal Transfer of Angiogenic MicroRNAs Regulate Cancer Cell Metastasis

(2013) Nobuyoshi Kosaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

Diverse functions of miR-125 family in different cell contexts

(2013) Yu-Meng Sun et al.   Journal of Hematology & Oncology

MicroRNAs in liver disease

(2013) Gyongyi Szabo et al.   Nature Reviews Gastroenterology & Hepatology

Let-7b Is Involved in the Inflammation and Immune Responses Associated with Helicobacter pylori Infection by Targeting Toll-Like Receptor 4

(2013) Gui-gen Teng et al.   PLoS One

MicroRNA-21 Knockout Improve the Survival Rate in DSS Induced Fatal Colitis through Protecting against Inflammation and Tissue Injury

(2013) Chenzhang Shi et al.   PLoS One

MicroRNA-150 Expression Induces Myeloid Differentiation of Human Acute Leukemia Cells and Normal Hematopoietic Progenitors

(2013) Valerie A. Morris et al.   PLoS One

Identification of microRNAs That Regulate TLR2-Mediated Trophoblast Apoptosis and Inhibition of IL-6 mRNA

(2013) Manish Garg et al.   PLoS One

Negative regulation of Toll-like receptor 4 signaling by IL-10-dependent microRNA-146b

(2013) G. Curtale et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of microRNAs in the immune system, inflammation and cancer

(2013) Jennifer Raisch   WORLD JOURNAL OF GASTROENTEROLOGY

Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs

(2013) Carolina Villarroya-Beltri et al.   Nature Communications

HCV-Induced miR-21 Contributes to Evasion of Host Immune System by Targeting MyD88 and IRAK1

(2013) Yanni Chen et al.   PLoS Pathogens

Quantitative Proteomics Reveals that miR-155 Regulates the PI3K-AKT Pathway in Diffuse Large B-Cell Lymphoma

(2012) Xin Huang et al.   AMERICAN JOURNAL OF PATHOLOGY

The down-regulation of miR-125b in chronic lymphocytic leukemias leads to metabolic adaptation of cells to a transformed state

(2012) E. Tili et al.   BLOOD

Attenuation of miR-126 Activity Expands HSC In Vivo without Exhaustion

(2012) Eric R. Lechman et al.   Cell Stem Cell

MicroRNAs in the regulation of TLR and RIG-I pathways

(2012) Yingke Li et al.   Cellular & Molecular Immunology

miR-9 enhances IL-2 production in activated human CD4+ T cells by repressing Blimp-1

(2012) Stefanie Thiele et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

microRNA-210 negatively regulates LPS-induced production of proinflammatory cytokines by targeting NF-κB1 in murine macrophages

(2012) Jianni Qi et al.   FEBS LETTERS

MicroRNA-7 inhibits tumor growth and metastasis by targeting the phosphoinositide 3-kinase/Akt pathway in hepatocellular carcinoma

(2012) YuXiang Fang et al.   HEPATOLOGY

The role of MicroRNAs miR-200b and miR-200c in TLR4 signaling and NF-κB activation

(2012) Erik B Wendlandt et al.   Innate Immunity

Increased microRNA-155 expression in the serum and peripheral monocytes in chronic HCV infection

(2012) Shashi Bala et al.   Journal of Translational Medicine

Selective autophagy degrades DICER and AGO2 and regulates miRNA activity

(2012) Derrick Gibbings et al.   NATURE CELL BIOLOGY

An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration

(2012) Sabrina M Lehmann et al.   NATURE NEUROSCIENCE

MicroRNA-126 Inhibits Tumor Cell Growth and Its Expression Level Correlates with Poor Survival in Non-Small Cell Lung Cancer Patients

(2012) Jiyun Yang et al.   PLoS One

MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response

(2012) M. Fabbri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients

(2012) Kaleb M Pauley et al.   ARTHRITIS RESEARCH & THERAPY

Overexpression of miR-125b, a Novel Regulator of Innate Immunity, in Eosinophilic Chronic Rhinosinusitis with Nasal Polyps

(2011) Xin-Hao Zhang et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Macrophage development from HSCs requires PU.1-coordinated microRNA expression

(2011) S. Ghani et al.   BLOOD

MicroRNA function in myeloid biology

(2011) R. M. O'Connell et al.   BLOOD

Enforced expression of miR-125b affects myelopoiesis by targeting multiple signaling pathways

(2011) E. Surdziel et al.   BLOOD

MicroRNA regulation of innate immune responses in epithelial cells

(2011) Rui Zhou et al.   Cellular & Molecular Immunology

Analysis of the host microRNA response toSalmonellauncovers the control of major cytokines by thelet-7family

(2011) Leon N Schulte et al.   EMBO JOURNAL

Identifying a Role for Toll-Like Receptor 3 in the Innate Immune Response to Chlamydia muridarum Infection in Murine Oviduct Epithelial Cells

(2011) Wilbert A. Derbigny et al.   INFECTION AND IMMUNITY

Let-7 microRNA–mediated regulation of IL-13 and allergic airway inflammation

(2011) Manish Kumar et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

MicroRNA Expression Profiles of Human Blood Monocyte-derived Dendritic Cells and Macrophages Reveal miR-511 as Putative Positive Regulator of Toll-like Receptor 4

(2011) Liina Tserel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-146ais a significant brake on autoimmunity, myeloproliferation, and cancer in mice

(2011) Mark P. Boldin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-γ

(2011) Feng Ma et al.   NATURE IMMUNOLOGY

PDGF induced microRNA alterations in cancer cells

(2011) Minghai Shao et al.   NUCLEIC ACIDS RESEARCH

MicroRNA-mediated downregulation of mTOR/FGFR3 controls tumor growth induced by Src-related oncogenic pathways

(2011) C Oneyama et al.   ONCOGENE

NF- B dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies

(2011) J. L. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNAs in NF- B signaling

(2011) X. Ma et al.   Journal of Molecular Cell Biology

Conserved Regulation of p53 Network Dosage by MicroRNA–125b Occurs through Evolving miRNA–Target Gene Pairs

(2011) Minh T. N. Le et al.   PLoS Genetics

miR-146a Suppresses Invasion of Pancreatic Cancer Cells

(2010) Y. Li et al.   CANCER RESEARCH

Function of miR-146a in Controlling Treg Cell-Mediated Regulation of Th1 Responses

(2010) Li-Fan Lu et al.   CELL

Regulation of MicroRNA Expression and Abundance during Lymphopoiesis

(2010) Stefan Kuchen et al.   IMMUNITY

Up-regulation of MicroRNA-155 in Macrophages Contributes to Increased Tumor Necrosis Factor α (TNFα) Production via Increased mRNA Half-life in Alcoholic Liver Disease

(2010) Shashi Bala et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IL-10 Inhibits miR-155 Induction by Toll-like Receptors

(2010) Claire E. McCoy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inducible microRNA-155 Feedback Promotes Type I IFN Signaling in Antiviral Innate Immunity by Targeting Suppressor of Cytokine Signaling 1

(2010) P. Wang et al.   JOURNAL OF IMMUNOLOGY

Estradiol Suppresses NF- B Activation through Coordinated Regulation of let-7a and miR-125b in Primary Human Macrophages

(2010) A. J. Murphy et al.   JOURNAL OF IMMUNOLOGY

Biological functions of microRNAs: a review

(2010) Yong Huang et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

STAT3 Activation of miR-21 and miR-181b-1 via PTEN and CYLD Are Part of the Epigenetic Switch Linking Inflammation to Cancer

(2010) Dimitrios Iliopoulos et al.   MOLECULAR CELL

Structural basis for 5′-nucleotide base-specific recognition of guide RNA by human AGO2

(2010) Filipp Frank et al.   NATURE

AP-1-Dependent miR-21 Expression Contributes to Chemoresistance in Cancer Stem Cell-Like SP Cells

(2010) Aya Misawa et al.   ONCOLOGY RESEARCH

Identification of differential and functionally active miRNAs in both anaplastic lymphoma kinase (ALK)+ and ALK- anaplastic large-cell lymphoma

(2010) O. Merkel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-125b expands hematopoietic stem cells and enriches for the lymphoid-balanced and lymphoid-biased subsets

(2010) A. G. L. Ooi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNAs enriched in hematopoietic stem cells differentially regulate long-term hematopoietic output

(2010) R. M. O'Connell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA miR-125a controls hematopoietic stem cell number

(2010) S. Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Widespread regulatory activity of vertebrate microRNA* species

(2010) J.-S. Yang et al.   RNA

MicroRNA-146a contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins

(2009) Yuanjia Tang et al.   ARTHRITIS AND RHEUMATISM

An Epigenetic Switch Involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 Links Inflammation to Cell Transformation

(2009) Dimitrios Iliopoulos et al.   CELL

Ars2 Links the Nuclear Cap-Binding Complex to RNA Interference and Cell Proliferation

(2009) Joshua J. Gruber et al.   CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

The Kinase Akt1 Controls Macrophage Response to Lipopolysaccharide by Regulating MicroRNAs

(2009) Ariadne Androulidaki et al.   IMMUNITY

miR-146a Is Critical for Endotoxin-induced Tolerance

(2009) Md A. Nahid et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21

(2009) Frederick J Sheedy et al.   NATURE IMMUNOLOGY

Identification of miR-145 and miR-146a as mediators of the 5q– syndrome phenotype

(2009) Daniel T Starczynowski et al.   NATURE MEDICINE

Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals

(2009) F. Bazzoni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MHC II in Dendritic Cells is Targeted to Lysosomes or T Cell-Induced Exosomes Via Distinct Multivesicular Body Pathways

(2009) Sonja I. Buschow et al.   TRAFFIC

Activated T cells recruit exosomes secreted by dendritic cells via LFA-1

(2008) E. N. M. Nolte-'t Hoen et al.   BLOOD

MicroRNAs: novel regulators in skin inflammation

(2008) E. Sonkoly et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

SMAD proteins control DROSHA-mediated microRNA maturation

(2008) Brandi N. Davis et al.   NATURE

Expression of microRNA-146 suppresses NF-κB activity with reduction of metastatic potential in breast cancer cells

(2008) D Bhaumik et al.   ONCOGENE