MicroRNA 21 Is a Homeostatic Regulator of Macrophage Polarization and Prevents Prostaglandin E2-Mediated M2 Generation

MicroRNA-155 Silencing Enhances Inflammatory Response and Lipid Uptake in Oxidized Low-Density Lipoprotein-Stimulated Human THP-1 Macrophages

(2016) Ri-sheng Huang et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Crosstalk between Prostaglandin E2 and Leukotriene B4 Regulates Phagocytosis in Alveolar Macrophages via Combinatorial Effects on Cyclic AMP

(2014) S. P. Lee et al.   JOURNAL OF IMMUNOLOGY

Misoprostol Impairs Female Reproductive Tract Innate Immunity against Clostridium sordellii

(2014) D. M. Aronoff et al.   JOURNAL OF IMMUNOLOGY

Leukotriene B4 Enhances the Generation of Proinflammatory MicroRNAs To Promote MyD88-Dependent Macrophage Activation

(2014) Z. Wang et al.   JOURNAL OF IMMUNOLOGY

Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin

(2014) Jan Mauer et al.   NATURE IMMUNOLOGY

EP4 and EP2 Receptor Activation of Protein Kinase A by Prostaglandin E2Impairs Macrophage Phagocytosis ofClostridium sordellii

(2013) Lisa M. Rogers et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

MicroRNAs in Immune Response and Macrophage Polarization

(2013) Gang Liu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

miR-125a-5p Regulates Differential Activation of Macrophages and Inflammation

(2013) Sami Banerjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-149 Negatively Regulates TLR-Triggered Inflammatory Response in Macrophages by Targeting MyD88

(2013) Guangxian Xu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

MicroRNA let-7c Regulates Macrophage Polarization

(2013) S. Banerjee et al.   JOURNAL OF IMMUNOLOGY

Prostaglandin E2-Induced Changes in Alveolar Macrophage Scavenger Receptor Profiles Differentially Alter Phagocytosis of Pseudomonas aeruginosa and Staphylococcus aureus Post-Bone Marrow Transplant

(2013) R. Domingo-Gonzalez et al.   JOURNAL OF IMMUNOLOGY

MyD88 as a target of microRNA-203 in regulation of lipopolysaccharide or Bacille Calmette-Guerin induced inflammatory response of macrophage RAW264.7 cells

(2013) Jun Wei et al.   MOLECULAR IMMUNOLOGY

MicroRNA-21 Knockout Improve the Survival Rate in DSS Induced Fatal Colitis through Protecting against Inflammation and Tissue Injury

(2013) Chenzhang Shi et al.   PLoS One

Arsenite evokes IL-6 secretion, autocrine regulation of STAT3 signaling, and miR-21 expression, processes involved in the EMT and malignant transformation of human bronchial epithelial cells

(2013) Fei Luo et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Prostaglandin E2 restrains macrophage maturation via E prostanoid receptor 2/protein kinase A signaling

(2012) Z. Zaslona et al.   BLOOD

RETRACTED: Suppressors of Cytokine Signaling 2 and 3 Diametrically Control Macrophage Polarization

(2012) Shaun Spence et al.   IMMUNITY

Identifying Functional MicroRNAs in Macrophages with Polarized Phenotypes

(2012) Joel W. Graff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SOCS3 Deficiency Promotes M1 Macrophage Polarization and Inflammation

(2012) H. Qin et al.   JOURNAL OF IMMUNOLOGY

CCR1-Mediated STAT3 Tyrosine Phosphorylation and CXCL8 Expression in THP-1 Macrophage-like Cells Involve Pertussis Toxin-Insensitive G 14/16 Signaling and IL-6 Release

(2012) M. M. K. Lee et al.   JOURNAL OF IMMUNOLOGY

Prostaglandin and the Suppression of Phagocyte Innate Immune Responses in Different Organs

(2012) Alexandra Medeiros et al.   MEDIATORS OF INFLAMMATION

A miR-19 regulon that controls NF-κB signaling

(2012) Michael P. Gantier et al.   NUCLEIC ACIDS RESEARCH

Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization

(2012) A. Arranz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysregulated expression of miR-146a contributes to age-related dysfunction of macrophages

(2011) Minghong Jiang et al.   AGING CELL

Blockade of prostaglandin E2 signaling through EP1 and EP3 receptors attenuates Flt3L-dependent dendritic cell development from hematopoietic progenitor cells

(2011) P. Singh et al.   BLOOD

MicroRNAs and the resolution phase of inflammation in macrophages

(2011) Muhammad M. Alam et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Leukotrienes Target F-actin/Cofilin-1 to Enhance Alveolar Macrophage Anti-fungal Activity

(2011) Mariana Morato-Marques et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA miR-21 Regulates the Metastatic Behavior of B16 Melanoma Cells

(2011) Chuan He Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extracellular Hepatitis C Virus Core Protein Activates STAT3 in Human Monocytes/Macrophages/Dendritic Cells via an IL-6 Autocrine Pathway

(2011) Robert S. Tacke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct Protein Kinase A Anchoring Proteins Direct Prostaglandin E2Modulation of Toll-like Receptor Signaling in Alveolar Macrophages

(2011) Sang-Hoon Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dendritic Cell-Specific ICAM-3-Grabbing Nonintegrin Expression on M2-Polarized and Tumor-Associated Macrophages Is Macrophage-CSF Dependent and Enhanced by Tumor-Derived IL-6 and IL-10

(2011) A. Dominguez-Soto et al.   JOURNAL OF IMMUNOLOGY

Suppressor of cytokine signaling (SOCS)1 is a key determinant of differential macrophage activation and function

(2011) Claire S. Whyte et al.   JOURNAL OF LEUKOCYTE BIOLOGY

MicroRNA-146a regulates both transcription silencing and translation disruption of TNF-α during TLR4-induced gene reprogramming

(2011) Mohamed El Gazzar et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils

(2011) Stephen J Galli et al.   NATURE IMMUNOLOGY

Modulation of K-Ras-Dependent Lung Tumorigenesis by MicroRNA-21

(2010) Mark E. Hatley et al.   CANCER CELL

Up-regulation of MicroRNA-155 in Macrophages Contributes to Increased Tumor Necrosis Factor α (TNFα) Production via Increased mRNA Half-life in Alcoholic Liver Disease

(2010) Shashi Bala et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

STAT3 Activation of miR-21 and miR-181b-1 via PTEN and CYLD Are Part of the Epigenetic Switch Linking Inflammation to Cancer

(2010) Dimitrios Iliopoulos et al.   MOLECULAR CELL

Efferocytosis impairs pulmonary macrophage and lung antibacterial function via PGE2/EP2 signaling

(2009) Alexandra I. Medeiros et al.   JOURNAL OF EXPERIMENTAL MEDICINE

MicroRNA-21 Is Up-Regulated in Allergic Airway Inflammation and Regulates IL-12p35 Expression

(2009) T. X. Lu et al.   JOURNAL OF IMMUNOLOGY

Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21

(2009) Frederick J Sheedy et al.   NATURE IMMUNOLOGY

miR-147, a microRNA that is induced upon Toll-like receptor stimulation, regulates murine macrophage inflammatory responses

(2009) G. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The PGE2-Stat3 interaction in doxorubicin-induced myocardial apoptosis

(2008) M. A. Frias et al.   CARDIOVASCULAR RESEARCH

TLR4/MYD88-dependent, LPS-induced synthesis of PGE2 by macrophages or dendritic cells prevents anti-CD3-mediated CD95L upregulation in T cells

(2008) R Weinlich et al.   CELL DEATH AND DIFFERENTIATION

MicroRNAs: Novel Regulators During the Immune Response

(2008) Yujing Bi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Effects of prostaglandin E2 on the subcellular localization of Epac-1 and Rap1 proteins during Fcγ-receptor-mediated phagocytosis in alveolar macrophages

(2007) Thomas G. Brock et al.   EXPERIMENTAL CELL RESEARCH