Canonical Wnt signaling in the oligodendroglial lineage-puzzles remain

Lithium chloride stimulates PLP and MBP expression in oligodendrocytes via Wnt/β-catenin and Akt/CREB pathways

(2015) D. Meffre et al.   NEUROSCIENCE

Oligodendrocyte-Encoded HIF Function Couples Postnatal Myelination and White Matter Angiogenesis

(2014) Tracy J. Yuen et al.   CELL

Wnt some lose some: transcriptional governance of stem cells by Wnt/ -catenin signaling

(2014) W.-H. Lien et al.   GENES & DEVELOPMENT

Pathophysiology of glia in perinatal white matter injury

(2014) Stephen A. Back et al.   GLIA

GSK3β regulates oligodendrogenesis in the dorsal microdomain of the subventricular zone via Wnt-β-catenin signaling

(2014) Kasum Azim et al.   GLIA

The translational biology of remyelination: Past, present, and future

(2014) Robin J. M. Franklin et al.   GLIA

Abrogation of  -Catenin Signaling in Oligodendrocyte Precursor Cells Reduces Glial Scarring and Promotes Axon Regeneration after CNS Injury

(2014) J. P. Rodriguez et al.   JOURNAL OF NEUROSCIENCE

Stage-Specific Regulation of Oligodendrocyte Development by Wnt/ -Catenin Signaling

(2014) Z.-M. Dai et al.   JOURNAL OF NEUROSCIENCE

TGF  Signaling Regulates the Timing of CNS Myelination by Modulating Oligodendrocyte Progenitor Cell Cycle Exit through SMAD3/4/FoxO1/Sp1

(2014) J. Palazuelos et al.   JOURNAL OF NEUROSCIENCE

GSK3β Promotes the Differentiation of Oligodendrocyte Precursor Cells via β-Catenin-Mediated Transcriptional Regulation

(2014) Liang Zhou et al.   MOLECULAR NEUROBIOLOGY

Parallel states of pathological Wnt signaling in neonatal brain injury and colon cancer

(2014) Stephen P J Fancy et al.   NATURE NEUROSCIENCE

Persistent Wnt/β-Catenin Signaling Determines Dorsalization of the Postnatal Subventricular Zone and Neural Stem Cell Specification into Oligodendrocytes and Glutamatergic Neurons

(2014) Kasum Azim et al.   STEM CELLS

Chronic hypoxia induces the activation of the Wnt/β-catenin signaling pathway and stimulates hippocampal neurogenesis in wild-type and APPswe-PS1ΔE9 transgenic mice in vivo

(2014) Lorena Varela-Nallar et al.   Frontiers in Cellular Neuroscience

Chromatin Effector Pygo2 Mediates Wnt-Notch Crosstalk to Suppress Luminal/Alveolar Potential of Mammary Stem and Basal Cells

(2013) Bingnan Gu et al.   Cell Stem Cell

Mobilization of progenitors in the subventricular zone to undergo oligodendrogenesis in the Theiler's virus model of multiple sclerosis: Implications for remyelination at lesions sites

(2013) M. Mecha et al.   EXPERIMENTAL NEUROLOGY

 -Catenin interacts with APC to regulate  -catenin proteolysis and transcriptional repression of Wnt target genes

(2013) S. H. Choi et al.   GENES & DEVELOPMENT

LRP6 exerts non-canonical effects on Wnt signaling during neural tube closure

(2013) Jason D. Gray et al.   HUMAN MOLECULAR GENETICS

Hypoxia-inducible Factor-2α-dependent Hypoxic Induction of Wnt10b Expression in Adipogenic Cells

(2013) Young-Kwon Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NG2 Cells in White Matter But Not Gray Matter Proliferate in Response to PDGF

(2013) R. A. Hill et al.   JOURNAL OF NEUROSCIENCE

Adenomatous Polyposis Coli Regulates Oligodendroglial Development

(2013) J. Lang et al.   JOURNAL OF NEUROSCIENCE

Wnt Signaling in Remyelination in Multiple Sclerosis: Friend or Foe?

(2013) Chong Xie et al.   MOLECULAR NEUROBIOLOGY

Oligodendrogliogenic and neurogenic adult subependymal zone neural stem cells constitute distinct lineages and exhibit differential responsiveness to Wnt signalling

(2013) Felipe Ortega et al.   NATURE CELL BIOLOGY

Oligodendrocyte Dynamics in the Healthy Adult CNS: Evidence for Myelin Remodeling

(2013) Kaylene M. Young et al.   NEURON

Mechanisms regulating the development of oligodendrocytes and central nervous system myelin

(2013) S. Mitew et al.   NEUROSCIENCE

HIF-1α Inhibits Wnt Signaling Pathway by Activating Sost Expression in Osteoblasts

(2013) Dafu Chen et al.   PLoS One

Limited TCF7L2 Expression in MS Lesions

(2013) Alexander Lürbke et al.   PLoS One

Pax6 Mediates ß-Catenin Signaling for Self-Renewal and Neurogenesis by Neocortical Radial Glial Stem Cells

(2013) Qini Gan et al.   STEM CELLS

Diabetes Risk Gene and Wnt Effector Tcf7l2/TCF4 Controls Hepatic Response to Perinatal and Adult Metabolic Demand

(2012) Sylvia F. Boj et al.   CELL

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

Wnt/β-Catenin Signaling and Disease

(2012) Hans Clevers et al.   CELL

The updated biology of hypoxia-inducible factor

(2012) Samantha N Greer et al.   EMBO JOURNAL

The many faces and functions of β-catenin

(2012) Tomas Valenta et al.   EMBO JOURNAL

Astrocyte-derived VEGF-A drives blood-brain barrier disruption in CNS inflammatory disease

(2012) Azeb Tadesse Argaw et al.   JOURNAL OF CLINICAL INVESTIGATION

Oligodendroglia metabolically support axons and contribute to neurodegeneration

(2012) Youngjin Lee et al.   NATURE

Separated at birth? The functional and molecular divergence of OLIG1 and OLIG2

(2012) Dimphna H. Meijer et al.   NATURE REVIEWS NEUROSCIENCE

Dual-Mode Modulation of Smad Signaling by Smad-Interacting Protein Sip1 Is Required for Myelination in the Central Nervous System

(2012) Qinjie Weng et al.   NEURON

Spatio-Temporal Expression Pattern of Frizzled Receptors after Contusive Spinal Cord Injury in Adult Rats

(2012) Pau Gonzalez et al.   PLoS One

Synergistic Inhibition of Wnt Pathway by HIF-1α and Osteoblast-Specific Transcription Factor Osterix (Osx) in Osteoblasts

(2012) Dafu Chen et al.   PLoS One

Targeted Disruption of the BCL9/ -Catenin Complex Inhibits Oncogenic Wnt Signaling

(2012) K. Takada et al.   Science Translational Medicine

Wnt Signaling and Forebrain Development

(2012) S. J. Harrison-Uy et al.   Cold Spring Harbor Perspectives in Biology

Secreted and Transmembrane Wnt Inhibitors and Activators

(2012) C.-M. Cruciat et al.   Cold Spring Harbor Perspectives in Biology

TCF/LEFs and Wnt Signaling in the Nucleus

(2012) K. M. Cadigan et al.   Cold Spring Harbor Perspectives in Biology

Arrested preoligodendrocyte maturation contributes to myelination failure in premature infants

(2011) Joshua R. Buser et al.   ANNALS OF NEUROLOGY

Canonical Wnt Signalling Requires the BMP Pathway to Inhibit Oligodendrocyte Maturation

(2011) Keith Feigenson et al.   ASN Neuro

Tcf7l2 is Tightly Controlled During Myelin Formation

(2011) Hui Fu et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Probing transcription-specific outputs of  -catenin in vivo

(2011) T. Valenta et al.   GENES & DEVELOPMENT

GSK3β negatively regulates oligodendrocyte differentiation and myelination in vivo

(2011) Kasum Azim et al.   GLIA

Hepatocyte γ-catenin compensates for conditionally deleted β-catenin at adherens junctions

(2011) Emily Diane Wickline et al.   JOURNAL OF HEPATOLOGY

Macroglial Plasticity and the Origins of Reactive Astroglia in Experimental Autoimmune Encephalomyelitis

(2011) F. Guo et al.   JOURNAL OF NEUROSCIENCE

Assessing the Role of the Cadherin/Catenin Complex at the Schwann Cell-Axon Interface and in the Initiation of Myelination

(2011) K. A. Lewallen et al.   JOURNAL OF NEUROSCIENCE

Wnt/ -Catenin Signaling Is an Essential and Direct Driver of Myelin Gene Expression and Myelinogenesis

(2011) M. Tawk et al.   JOURNAL OF NEUROSCIENCE

Changed Histone Acetylation Patterns in Normal-Appearing White Matter and Early Multiple Sclerosis Lesions

(2011) X. Pedre et al.   JOURNAL OF NEUROSCIENCE

SRY-Box Containing Gene 17 Regulates the Wnt/ -Catenin Signaling Pathway in Oligodendrocyte Progenitor Cells

(2011) L.-J. Chew et al.   JOURNAL OF NEUROSCIENCE

Anti-TANKyrase weapons promote myelination

(2011) Patrizia Casaccia   NATURE NEUROSCIENCE

Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination

(2011) Stephen P J Fancy et al.   NATURE NEUROSCIENCE

Naked1 Antagonizes Wnt Signaling by Preventing Nuclear Accumulation of β-Catenin

(2011) Terence J. Van Raay et al.   PLoS One

Contrasting Expression of Canonical Wnt Signaling Reporters TOPGAL, BATGAL and Axin2LacZ during Murine Lung Development and Repair

(2011) Denise Al Alam et al.   PLoS One

Winning WNT: Race to Wnt signaling inhibitors

(2011) K. Watanabe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Updated Overview on Wnt Signaling Pathways

(2010) Tata Purushothama Rao et al.   CIRCULATION RESEARCH

Overcoming remyelination failure in multiple sclerosis and other myelin disorders

(2010) Stephen P.J. Fancy et al.   EXPERIMENTAL NEUROLOGY

β-catenin mediates insulin-like growth factor-I actions to promote cyclin D1 mRNA expression, cell proliferation and survival in oligodendroglial cultures

(2010) Ping Ye et al.   GLIA

Wnts Influence the Timing and Efficiency of Oligodendrocyte Precursor Cell Generation in the Telencephalon

(2010) A. J. Langseth et al.   JOURNAL OF NEUROSCIENCE

Myelination and support of axonal integrity by glia

(2010) Klaus-Armin Nave   NATURE

O2 regulates stem cells through Wnt/β-catenin signalling

(2010) Jolly Mazumdar et al.   NATURE CELL BIOLOGY

Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α

(2010) Curtis A Thorne et al.   Nature Chemical Biology

Regulation of TGF-  signaling by Smad7

(2009) X. Yan et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Differential activity of Wnt/β-catenin signaling in the embryonic mouse thalamus

(2009) Krista K. Bluske et al.   DEVELOPMENTAL DYNAMICS

Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS

(2009) S. P.J. Fancy et al.   GENES & DEVELOPMENT

Tenascin C and tenascin R similarly prevent the formation of myelin membranes in a RhoA-dependent manner, but antagonistically regulate the expression of myelin basic protein via a separate pathway

(2009) Tim Czopka et al.   GLIA

Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation

(2009) Bingnan Gu et al.   JOURNAL OF CELL BIOLOGY

A Genome-Wide Screen for Spatially Restricted Expression Patterns Identifies Transcription Factors That Regulate Glial Development

(2009) H. Fu et al.   JOURNAL OF NEUROSCIENCE

Wnt signaling is sufficient to perturb oligodendrocyte maturation

(2009) Keith Feigenson et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

EGF-Induced ERK Activation Promotes CK2-Mediated Disassociation of α-Catenin from β-Catenin and Transactivation of β-Catenin

(2009) Haitao Ji et al.   MOLECULAR CELL

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

(2009) Shih-Min A. Huang et al.   NATURE

Small molecule–mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

(2009) Baozhi Chen et al.   Nature Chemical Biology

HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the β-catenin–TCF interaction

(2009) Feng Ye et al.   NATURE NEUROSCIENCE

Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination

(2009) Yueting Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wnt/ -catenin signaling is required for CNS, but not non-CNS, angiogenesis

(2009) R. Daneman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GSK3: a multifaceted kinase in Wnt signaling

(2009) Dianqing Wu et al.   TRENDS IN BIOCHEMICAL SCIENCES

The function of BCL9 in Wnt/β-catenin signaling and colorectal cancer cells

(2008) Marc de la Roche et al.   BMC CANCER

Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis

(2008) T. Kuhlmann et al.   BRAIN

Hypoxia-Inducible Factor-1  Obstructs a Wnt Signaling Pathway by Inhibiting the hARD1-Mediated Activation of  -Catenin

(2008) J.-H. Lim et al.   CANCER RESEARCH

Wnt signaling determines ventral spinal cord cell fates in a time-dependent manner

(2008) W. Yu et al.   DEVELOPMENT

Frizzled 8a function is required for oligodendrocyte development in the zebrafish spinal cord

(2008) Suhyun Kim et al.   DEVELOPMENTAL DYNAMICS

Axin and GSK3- control Smad3 protein stability and modulate TGF- signaling

(2008) X. Guo et al.   GENES & DEVELOPMENT

Smad7 Stabilizes β-Catenin Binding to E-cadherin Complex and Promotes Cell-Cell Adhesion

(2008) Yi Tang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Wnts acting through canonical and noncanonical signaling pathways exert opposite effects on hippocampal synapse formation

(2008) Elizabeth K Davis et al.   Neural Development