Peptide–MHC Class I Tetramers Can Fail To Detect Relevant Functional T Cell Clonotypes and Underestimate Antigen-Reactive T Cell Populations
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Peptide–MHC Class I Tetramers Can Fail To Detect Relevant Functional T Cell Clonotypes and Underestimate Antigen-Reactive T Cell Populations
Authors
Keywords
-
Journal
JOURNAL OF IMMUNOLOGY
Volume 200, Issue 7, Pages 2263-2279
Publisher
The American Association of Immunologists
Online
2018-02-26
DOI
10.4049/jimmunol.1700242
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- VDJdb: a curated database of T-cell receptor sequences with known antigen specificity
- (2017) Mikhail Shugay et al. NUCLEIC ACIDS RESEARCH
- Identifying T Cell Receptors from High-Throughput Sequencing: Dealing with Promiscuity in TCRα and TCRβ Pairing
- (2017) Edward S. Lee et al. PLoS Computational Biology
- IGF2 mRNA binding protein-2 is a tumor promoter that drives cancer proliferation through its client mRNAs IGF2 and HMGA1
- (2017) Ning Dai et al. eLife
- Human leucocyte antigen class I-redirected anti-tumour CD4+T cells require a higher T cell receptor binding affinity for optimal activity than CD8+T cells
- (2016) M. P. Tan et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Long-Lasting Complete Responses in Patients with Metastatic Melanoma after Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes and an Attenuated IL2 Regimen
- (2016) R. Andersen et al. CLINICAL CANCER RESEARCH
- Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity
- (2016) David K. Cole et al. JOURNAL OF CLINICAL INVESTIGATION
- T-cell libraries allow simple parallel generation of multiple peptide-specific human T-cell clones
- (2016) Sarah M. Theaker et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Control of T cell antigen reactivity via programmed TCR downregulation
- (2016) Alena M Gallegos et al. NATURE IMMUNOLOGY
- Detection, phenotyping, and quantification of antigen-specific T cells using a peptide-MHC dodecamer
- (2016) Jun Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Low-affinity CD4+ T cells are major responders in the primary immune response
- (2016) Ryan J. Martinez et al. Nature Communications
- The RNA Binding Protein IMP2 Preserves Glioblastoma Stem Cells by Preventing let-7 Target Gene Silencing
- (2016) Nils Degrauwe et al. Cell Reports
- T Cell Antigen Receptor Recognition of Antigen-Presenting Molecules
- (2015) Jamie Rossjohn et al. Annual Review of Immunology
- αβ T cell receptors as predictors of health and disease
- (2015) Meriem Attaf et al. Cellular & Molecular Immunology
- T cell receptor binding affinity governs the functional profile of cancer-specific CD8+T cells
- (2015) M. P. Tan et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- More tricks with tetramers: a practical guide to staining T cells with peptide-MHC multimers
- (2015) Garry Dolton et al. IMMUNOLOGY
- Enhanced Detection of Antigen-Specific CD4+T Cells Using Altered Peptide Flanking Residue Peptide–MHC Class II Multimers
- (2015) Christopher J. Holland et al. JOURNAL OF IMMUNOLOGY
- MiXCR: software for comprehensive adaptive immunity profiling
- (2015) Dmitriy A Bolotin et al. NATURE METHODS
- IMP3 promotes stem-like properties in triple-negative breast cancer by regulating SLUG
- (2015) S Samanta et al. ONCOGENE
- Lower Affinity T Cells are Critical Components and Active Participants of the Immune Response
- (2015) Ryan J. Martinez et al. Frontiers in Immunology
- Oncofetal Protein IMP3, a New Cancer Biomarker
- (2014) Yuna Gong et al. ADVANCES IN ANATOMIC PATHOLOGY
- Comparison of peptide-major histocompatibility complex tetramers and dextramers for the identification of antigen-specific T cells
- (2014) G. Dolton et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- β-Cell–Specific CD8 T Cell Phenotype in Type 1 Diabetes Reflects Chronic Autoantigen Exposure
- (2014) Ania Skowera et al. DIABETES
- Structural basis for ineffective T-cell responses to MHC anchor residue-improved “heteroclitic” peptides
- (2014) Florian Madura et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Antibody Stabilization of Peptide–MHC Multimers Reveals Functional T Cells Bearing Extremely Low-Affinity TCRs
- (2014) Katie Tungatt et al. JOURNAL OF IMMUNOLOGY
- Transnuclear TRP1-Specific CD8 T Cells with High or Low Affinity TCRs Show Equivalent Antitumor Activity
- (2013) S. K. Dougan et al. Cancer Immunology Research
- Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs): post-transcriptional drivers of cancer progression?
- (2012) Jessica L. Bell et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Different affinity windows for virus and cancer-specific T-cell receptors: Implications for therapeutic strategies
- (2012) Milos Aleksic et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cells
- (2012) M. Janiszewska et al. GENES & DEVELOPMENT
- Autoreactive T cells bypass negative selection and respond to self-antigen stimulation during infection
- (2012) Sarah Enouz et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IMP2 Expression Distinguishes Endometrioid From Serous Endometrial Adenocarcinomas
- (2011) Liping Zhang et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- A Novel Tumor Antigen Derived from Enhanced Degradation of Bax Protein in Human Cancers
- (2011) C. T. Nunes et al. CANCER RESEARCH
- Structural and biophysical determinants of αβ T-cell antigen recognition
- (2011) John S. Bridgeman et al. IMMUNOLOGY
- High prevalence of low affinity peptide–MHC II tetramer–negative effectors during polyclonal CD4+T cell responses
- (2011) Joseph J. Sabatino et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Isolation of viable antigen-specific CD8+ T cells based on membrane-bound tumor necrosis factor (TNF)-α expression
- (2011) Danielle Haney et al. JOURNAL OF IMMUNOLOGICAL METHODS
- The Tetramer Transformation
- (2011) P. C. Doherty JOURNAL OF IMMUNOLOGY
- Anti-CD8 Antibodies Can Trigger CD8+ T Cell Effector Function in the Absence of TCR Engagement and Improve Peptide-MHCI Tetramer Staining
- (2011) M. Clement et al. JOURNAL OF IMMUNOLOGY
- Persistent viral infection in humans can drive high frequency low-affinity T-cell expansions
- (2010) Naeem Khan et al. IMMUNOLOGY
- Modification of MHC Anchor Residues Generates Heteroclitic Peptides That Alter TCR Binding and T Cell Recognition
- (2010) D. K. Cole et al. JOURNAL OF IMMUNOLOGY
- Tricks with tetramers: how to get the most from multimeric peptide-MHC
- (2009) Linda Wooldridge et al. IMMUNOLOGY
- Germ Line-governed Recognition of a Cancer Epitope by an Immunodominant Human T-cell Receptor
- (2009) David K. Cole et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Complete but curtailed T-cell response to very low-affinity antigen
- (2009) Dietmar Zehn et al. NATURE
- Detection of low avidity CD8+ T cell populations with coreceptor-enhanced peptide-major histocompatibility complex class I tetramers
- (2008) J. Joseph Melenhorst et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Protein kinase inhibitors substantially improve the physical detection of T-cells with peptide-MHC tetramers
- (2008) Anna Lissina et al. JOURNAL OF IMMUNOLOGICAL METHODS
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started