β-Cell–Specific CD8 T Cell Phenotype in Type 1 Diabetes Reflects Chronic Autoantigen Exposure

Trials in type 1 diabetes: Antigen-specific therapies

(2013) Ken T. Coppieters et al.   CLINICAL IMMUNOLOGY

A Molecular Basis for the Control of Preimmune Escape Variants by HIV-Specific CD8+ T Cells

(2013) Kristin Ladell et al.   IMMUNITY

Superior T memory stem cell persistence supports long-lived T cell memory

(2013) Enrico Lugli et al.   JOURNAL OF CLINICAL INVESTIGATION

Interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo-controlled trials

(2013) Antoinette Moran et al.   LANCET

Immunotherapy for T1DM—still not there yet

(2013) Raffaella Buzzetti   Nature Reviews Endocrinology

Antigen Targets of Type 1 Diabetes Autoimmunity

(2013) B. O. Roep et al.   Cold Spring Harbor Perspectives in Medicine

Brilliant violet fluorophores: A new class of ultrabright fluorescent compounds for immunofluorescence experiments

(2012) Pratip K. Chattopadhyay et al.   CYTOMETRY PART A

Circulating Preproinsulin Signal Peptide-Specific CD8 T Cells Restricted by the Susceptibility Molecule HLA-A24 Are Expanded at Onset of Type 1 Diabetes and Kill  -Cells

(2012) D. Kronenberg et al.   DIABETES

Zinc transporter (ZnT)8186–194 is an immunodominant CD8+ T cell epitope in HLA-A2+ type 1 diabetic patients

(2012) M. Scotto et al.   DIABETOLOGIA

Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients

(2012) Ken T. Coppieters et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Holoendemic Malaria Exposure Is Associated with Altered Epstein-Barr Virus-Specific CD8+T-Cell Differentiation

(2012) Pratip K. Chattopadhyay et al.   JOURNAL OF VIROLOGY

TCR clonotypes modulate the protective effect of HLA class I molecules in HIV-1 infection

(2012) Huabiao Chen et al.   NATURE IMMUNOLOGY

Structural basis for the killing of human beta cells by CD8+ T cells in type 1 diabetes

(2012) Anna M Bulek et al.   NATURE IMMUNOLOGY

Identification, isolation and in vitro expansion of human and nonhuman primate T stem cell memory cells

(2012) Enrico Lugli et al.   Nature Protocols

Identification of novel HLA-A*0201-restricted cytotoxic T lymphocyte epitopes from Zinc Transporter 8

(2012) Shufa Li et al.   VACCINE

Diabetogenic T lymphocytes in human Type 1 diabetes

(2011) Bart O Roep et al.   CURRENT OPINION IN IMMUNOLOGY

Immunology of Diabetes Society T-Cell Workshop: HLA class I tetramer-directed epitope validation initiative T-Cell Workshop Report-HLA Class I Tetramer Validation Initiative

(2011) R. Mallone et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Structural and biophysical determinants of αβ T-cell antigen recognition

(2011) John S. Bridgeman et al.   IMMUNOLOGY

Bias in the αβ T-cell repertoire: implications for disease pathogenesis and vaccination

(2011) John J Miles et al.   IMMUNOLOGY AND CELL BIOLOGY

A Single Autoimmune T Cell Receptor Recognizes More Than a Million Different Peptides

(2011) Linda Wooldridge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial

(2011) Tihamer Orban et al.   LANCET

A human memory T cell subset with stem cell–like properties

(2011) Luca Gattinoni et al.   NATURE MEDICINE

Viruses and Cytotoxic T Lymphocytes in Type 1 Diabetes

(2010) Ken T. Coppieters et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Simultaneous Detection of Circulating Autoreactive CD8+ T-Cells Specific for Different Islet Cell-Associated Epitopes Using Combinatorial MHC Multimers

(2010) J. H. Velthuis et al.   DIABETES

Tricks with tetramers: how to get the most from multimeric peptide-MHC

(2009) Linda Wooldridge et al.   IMMUNOLOGY

Public clonotype usage identifies protective Gag-specific CD8+T cell responses in SIV infection

(2009) David A. Price et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Analysis of islet inflammation in human type 1 diabetes

(2008) A. Willcox et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Techniques to improve the direct ex vivo detection of low frequency antigen-specific CD8+T cells with peptide-major histocompatibility complex class I tetramers

(2008) Pratip K. Chattopadhyay et al.   CYTOMETRY PART A

Phenotype and function of human T lymphocyte subsets: Consensus and issues

(2008) Victor Appay et al.   CYTOMETRY PART A

Association of Graves’ Disease and Prevalence of Circulating IFN-γ-producing CD28− T Cells

(2008) Zhiping Sun et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Protein kinase inhibitors substantially improve the physical detection of T-cells with peptide-MHC tetramers

(2008) Anna Lissina et al.   JOURNAL OF IMMUNOLOGICAL METHODS

The cytolytic enzymes granyzme A, granzyme B, and perforin: expression patterns, cell distribution, and their relationship to cell maturity and bright CD57 expression

(2008) P. K. Chattopadhyay et al.   JOURNAL OF LEUKOCYTE BIOLOGY